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http://dx.doi.org/10.13065/jksdh.2015.15.06.941

Surgical therapy of keratocystic odontogenic tumors  

Oh, Ji-Su (Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University)
Kim, Su-Gwan (Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University)
Publication Information
Journal of Korean society of Dental Hygiene / v.15, no.6, 2015 , pp. 941-946 More about this Journal
Abstract
Objectives: Since World Health Organization reclassified the odontogenic keratocyst as a keratocystic odontogenic tumor(KCOT) in 2005, management of KCOT remains controversial. The purpose of the this study is to present a current concept of the treatment of the KCOT. Methods: Recent articles were focused on the method of the surgical therapy and the recurrence rate of KCOT. Results: The treatment modality is divided into conservative treatment-such as simple enucleation with or without curettage or marsupialization-and aggressive treatment including peripheral ostectomy, chemical curettage with Carnoy's solution, and resection. Conclusions: Keratocystic odontogenic tumors have higher recurrence rates than other odontogenic lesions; thus, the selected type of treatment is very important.
Keywords
decompression; jaw cyst; odontogenic cyst; recurrence;
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Times Cited By KSCI : 2  (Citation Analysis)
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1 Kaczmarzyk T, Mojsa I, Stypulkowska J. A systematic review of the recurrence rate for keratocystic odontogenic tumour in relation to treatment modalities. Int J Oral Maxillofac Surg 2012; 41(6): 756-67. http://dx.doi.org/10.1016/j.ijom.2012.02.008.   DOI
2 Sansare K, Raghav M, Mupparapu M, Mundada N, Karjodkar FR, Bansal S, et al. Keratocystic odontogenic tumor: systematic review with analysis of 72 additional cases from Mumbai, India. Oral Surg Oral Med Oral Pathol Oral Radiol 2013; 115(1): 128-39. http://dx.doi.org/10.1016/j.oooo.2012.10.005.   DOI
3 Philipsen HP. Keratocystic odontogenic tumour. In: World Health Organization classification of tumours. Pathology and genetics of head and neck tumours. Edited by Barnes L EJ, Reichart P, Sidransky D: Lyon : International Agency for Research on Cancer; 2005: 306-7.
4 Madras J, Lapointe H. Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour. J Can Dent Assoc 2008; 74(2): 165-65.
5 Telles DC, Castro WH, Gomez RS, Souto GR, Mesquita RA. Morphometric evaluation of keratocystic odontogenic tumor before and after marsupialization. Braz Oral Res 2013; 27(6): 496-502. http://dx.doi.org/10.1590/S1806-83242013000600009.   DOI
6 Morgan TA, Burton CC, Qian F. A retrospective review of treatment of the odontogenic keratocyst. J Oral Maxillofac Surg 2005; 63(5): 635-9.   DOI
7 Johnson NR, Batstone MD, Savage NW. Management and recurrence of keratocystic odontogenic tumor: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol 2013; 116(4): e271-6. http://dx.doi.org/10.1016/j.oooo.2011.12.028.   DOI
8 Jafaripozve N, Jafaripozve S, Khorasgani MA. Kerathocyst Odontogenic Tumor: Importance of selection the best treatment modality and a periodical follow-up to prevent from recurrence: a case report and literature review. Int J Prev Med 2013; 4(8): 967-70.
9 Neville BW, Damm DD, Allen CM, Bouquot JE. Oral &Maxillofacial Pathology. 2nd ed. Philadelphia: WB Saunders; 2002: 493-540.
10 Nayak MT, Singh A, Singhvi A, Sharma R. Odontogenic keratocyst: What is in the name? J Nat Sci Biol Med 2013; 4(2): 282-5. http://dx.doi.org/10.4103/0976-9668.116968.   DOI
11 Hong YY, Yu FY, Qu JF, Chen F, Li TJ. Fibroblasts regulate variable aggressiveness of syndromic keratocystic and non-syndromic odontogenic tumors. J Dent Res 2014; 93(9): 904-10. http://dx.doi.org/10.1177/0022034514542108.   DOI
12 Nakamura N, Mitsuyasu T, Mitsuyasu Y, Taketomi T, Higuchi Y, Ohishi M. Marsupialization for odontogenic keratocysts: long-term follow-up analysis of the effects and changes in growth characteristics. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 94(5): 543-53.   DOI
13 Simiyu BN, Butt F, Dimba EA, Wagaiyu EG, Awange DO, Guthua SW, et al. Keratocystic odontogenic tumours of the jaws and associated pathologies: a 10-year clinicopathologic audit in a referral teaching hospital in Kenya. J Craniomaxillofac Surg 2013; 41(3): 230-4. http://dx.doi.org/10.1016/j.jcms.2012.09.006.   DOI
14 de Molon RS, Verzola MH, Pires LC, Mascarenhas VI, da Silva RB, Cirelli JA, et al. Five years follow-up of a keratocyst odontogenic tumor treated by marsupialization and enucleation: A case report and literature review. Contemp Clin Dent 2015; 6(Suppl 1): S106-10. http://dx.doi.org/10.4103/0976-237X.152963.   DOI
15 Marker P, Brondum N, Clausen PP, Bastian HL. Treatment of large odontogenic keratocysts by decompression and later cystectomy: a long-term follow-up and a histologic study of 23 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996; 82(2): 122-31.   DOI
16 Finkelstein MW, Hellstein JW, Lake KS, Vincent SD. Keratocystic odontogenic tumor: a retrospective analysis of genetic, immunohistochemical and therapeutic features. Proposal of a multicenter clinical survey tool. Oral Surg Oral Med Oral Pathol Oral Radiol 2013; 116(1): 75-83. http://dx.doi.org/10.1016/j.oooo.2013.03.018.   DOI
17 Boffano P, Ruga E, Gallesio C. Keratocystic odontogenic tumor(odontogenic keratocyst): preliminary retrospective review of epidemiologic, clinical, and radiologic features of 261 lesions from University of Turin. J Oral Maxillofac Surg 2010; 68(12): 2994-9. http://dx.doi.org/10.4103/0976-237X.152963.   DOI
18 Gosau M, Draenert FG, Muller S, Frerich B, Burgers R, Reichert TE, et al. Two modifications in the treatment of keratocystic odontogenic tumors(KCOT) and the use of Carnoy's solution(CS)--a retrospective study lasting between 2 and 10 years. Clin Oral Investig 2010; 14(1): 27-34. http://dx.doi.org/10.1007/s00784-009-0264-6.   DOI
19 Mendes RA, Carvalho JF, van der Waal I. Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features. Oral Oncol 2010; 46(4): 219-25. http://dx.doi.org/10.1016/j.oraloncology.2010.01.012.   DOI
20 August M, Faquin WC, Troulis MJ, Kaban LB. Dedifferentiation of odontogenic keratocyst epithelium after cyst decompression. J Oral Maxillofac Surg 2003; 61(6): 678-83; discussion 83-4.   DOI
21 Shudou H, Sasaki M, Yamashiro T, Tsunomachi S, Takenoshita Y, Kubota Y, et al. Marsupialisation for keratocystic odontogenic tumours in the mandible: longitudinal image analysis of tumour size using 3D visualised CT scans. Int J Oral Maxillofac Surg 2012; 41(3): 290-6. http://dx.doi.org/10.1016/j.ijom.2011.10.015.   DOI
22 Chuan L, Hongzhi Z, Rui H, Yuxiang D, Ruifeng Q, Kaijin H. Clinical observation of a conservative treatment for large keratocystic odontogenic tumors in the mandible: enucleation followed by open packing. Hua Xi Kou Qiang Yi Xue Za Zhi 2014; 32(6): 566-9.
23 Kinard BE, Chuang SK, August M, Dodson TB. For treatment of odontogenic keratocysts, is enucleation, when compared to decompression, a less complex management protocol? J Oral Maxillofac Surg 2015; 73(4): 641-8. http://dx.doi.org/10.1016/j.joms.2014.11.001.   DOI
24 Sanchez-Burgos R, Gonzalez-Martin-Moro J, Perez-Fernandez E, Burgueno-Garcia M. Clinical, radiological and therapeutic features of keratocystic odontogenic tumours: a study over a decade. J Clin Exp Dent 2014; 6(3): e259-64. http://dx.doi.org/10.4317/jced. 51408.
25 Pogrel MA. The keratocystic odontogenic tumour (KCOT)-an odyssey. Int J Oral Maxillofac Surg 2015 May 21. http://dx.doi.org/10.1016/j.ijom.2015.03.008. [Epub ahead of print].
26 Padaki P, Laverick S, Bounds G. Conservative management of a large keratocystic odontogenic tumour. J Surg Case Rep 2014; 2014(9) http://dx.doi.org/10.1093/jscr/rju091.
27 Brannon RB. The odontogenic keratocyst. A clinicopathologic study of 312 cases. Part I. Clinical features. Oral Surg Oral Med Oral Pathol 1976; 42(1): 54-72.   DOI
28 Roopak B, Singh M, Shah A, Patel G. Keratocystic odontogenic tumor: treatment modalities: study of 3 cases. Niger J Clin Pract 2014; 17(3): 378-83. http://dx.doi.org/10.4103/1119-3077.130251.   DOI
29 Titinchi F, Nortje CJ. Keratocystic odontogenic tumor: a recurrence analysis of clinical and radiographic parameters. Oral Surg Oral Med Oral Pathol Oral Radiol 2012; 114(1): 136-42. http://dx.doi.org/10.1016/j.oooo.2012.01.032.   DOI
30 Pitak-Arnnop P, Chaine A, Oprean N, Dhanuthai K, Bertrand JC, Bertolus C. Management of odontogenic keratocysts of the jaws: a ten-year experience with 120 consecutive lesions. J Craniomaxillofac Surg 2010; 38(5): 358-64. http://dx.doi.org/10.1016/j.jcms.2009.10.006.   DOI
31 Lee DG, Yoo WK. Relations between oral health status and subjective oral health recognition in Korean adolescents. J Korean Soc of Dent Hyg 2015; 15(4): 593-602. http://www.riss.kr/link?id=A100825628.   DOI
32 Ju OJ, Jang YJ, Jung JA. Oral health awareness and behavior affecting oral health indexes. J Korean Soc of Dent Hyg 2013; 13(1): 69-81. http://www.riss.kr/link?id=A99769553.   DOI