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http://dx.doi.org/10.13065/jksdh.2014.14.01.117

Antibacterial effect on leaf-extract from Nelumbo nucifera against oral microorganism  

Huh, Man-Kyu (Department of Molecular Biology, Dongeui University)
Kim, Hye-Jin (Department of Dental Hygiene, Dongeui University)
Publication Information
Journal of Korean society of Dental Hygiene / v.14, no.1, 2014 , pp. 117-122 More about this Journal
Abstract
Objectives : The purpose of the study is to investigate the activities of Nelumbo nucifera leaf extracts on Streptococcus mutans, Streptococcus mitis, Streptococcus sobrinus, Porphyromonas gingivalis, Prevotella intermedia, and Treponema denticola. Methods : The inhibitory effect of lotus leaf extracts on the growth of oral bacteria was assessed in experiments with extracts from freshly harvested and pulverized lotus leaves and bacterial cultures of dental caries. Results : The results showed that N. nucifera extracts possess antimicrobial activity on all bacterial strains. The minimal inhibitory concentration (MIC) values varied from 4 mg/ml to 10 mg/ml against antimicrobial activity. The relative growth ratio (RGR) against of N. nucifera extracts were determined as 50% in concentration of 4.0 mg/ml. The extract of N. nucifera was effective in reducing on the glucosyltransferase (GTase) activity of six strains in vitro. Conclusions : Methanol extracts of lotus leaves showed antimicrobial effects on three bacterial species causing dental caries and three bacterial species causing periodontitis, as well as inhibitory effects on GTase activity.
Keywords
antibacterial effect; Nelumbo nucifera leaf; oral microorganism;
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Times Cited By KSCI : 7  (Citation Analysis)
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