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Beneficial effect of vitamin K on bone health  

Jang, Young-Ho (Dept. of Dental Hygiene, Andong Science College)
Publication Information
Journal of Korean society of Dental Hygiene / v.11, no.4, 2011 , pp. 419-426 More about this Journal
Abstract
Originally, vitamin K was defined as a factor for blood coagulation. Now more attention is focused on vitamin K for bone metabolism and bone health. Vitamin K is a coenzyme for glutamate carboxylase which converts glutamate residues to ${\gamma}$-carboxyglutamate(Gla) residues. Gla residues have calcium binding ability and bound to hydroxyapatite crystals in bone. Vitamin K promotes the carboxylation of osteocalcin and matrix Gla-protein, vitamin K-dependent proteins and improves bone mineral density and bone mass. Vitamin K deficiency causes reductions in bone mineral density and increases the risk of osteoporotic bone fractures, resulting from undercarboxylated osteocalcin. This paper is to provide a brief information of vitamin K and its role in bone health.
Keywords
bone health; osteocalcin; vitamin K;
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Times Cited By KSCI : 2  (Citation Analysis)
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