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http://dx.doi.org/10.17245/jdapm.2021.21.5.471

Anesthetic experience: congenital methemoglobinemia due to hemoglobin M  

Ri, Hyunsu (Department of Anesthesiology and Pain Medicine, Kyungpook National University Hospital)
Park, Youngje (Department of Anesthesiology and Pain Medicine, Kyungpook National University Hospital)
Jeon, Younghoon (Department of Anesthesiology and Pain Medicine, Kyungpook National University Hospital)
Publication Information
Journal of Dental Anesthesia and Pain Medicine / v.21, no.5, 2021 , pp. 471-474 More about this Journal
Abstract
Methemoglobinemia is rare. It is classified into two types: congenital methemoglobinemia and acquired methemoglobinemia. Methemoglobin is incapable of binding oxygen, leading to complications such as cyanosis, dyspnea, headache, and heart failure. In the present case, a 35-year-old man with congenital methemoglobinemia underwent general anesthesia for thyroidectomy. The patient was diagnosed with hemoglobin M at 7 years of age. Ventilation was performed with FiO2 1.0. Arterial blood gas analysis showed that the pH was 7.4, PaO2 439 mmHg, PaCO2 40.5 mmHg, oxyhemoglobin level of 83.2%, and methemoglobin level of 15.5%. The patient had a stable course, although cyanosis was observed during surgery.
Keywords
General Anesthesia; Hemoglobin M; Methemoglobin; Methemoglobinemia;
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