In vitro evaluation of octenidine as an antimicrobial agent against Staphylococcus epidermidis in disinfecting the root canal system |
Chum, Jia Da
(Department of Dental Surgery, School of Dentistry, International Medical University)
Lim, Darryl Jun Zhi (Department of Dental Surgery, School of Dentistry, International Medical University) Sheriff, Sultan Omer (Clinical Dentistry, School of Dentistry, International Medical University) Pulikkotil, Shaju Jacob (Clinical Dentistry, School of Dentistry, International Medical University) Suresh, Anand (Department of Conservative Dentistry and Endodontics, Penang International Dental College) Davamani, Fabian (School of Health Sciences, International Medical University) |
1 | Anuradha B, Indira R, Lalitha M, Sriram T. A new irrigant against E. faecalis in root canal disinfection. Biosci Biotechnol Res Asia 2014;11:121-127. DOI |
2 | Ercan E, Ozekinci T, Atakul F, Gul K. Antibacterial activity of 2% chlorhexidine gluconate and 5.25% sodium hypochlorite in infected root canal: in vivo study. J Endod 2004;30:84-87. DOI |
3 | Jeansonne MJ, White RR. A comparison of 2.0% chlorhexidine gluconate and 5.25% sodium hypochlorite as antimicrobial endodontic irrigants. J Endod 1994;20:276-278. DOI |
4 | Vahdaty A, Pitt Ford TR, Wilson RF. Efficacy of chlorhexidine in disinfecting dentinal tubules in vitro. Endod Dent Traumatol 1993;9:243-248. DOI |
5 | Vianna ME, Gomes BP, Berber VB, Zaia AA, Ferraz CC, de Souza-Filho FJ. In vitro evaluation of the antimicrobial activity of chlorhexidine and sodium hypochlorite. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;97:79-84. DOI |
6 | Ruff ML, McClanahan SB, Babel BS. In vitro antifungal efficacy of four irrigants as a final rinse. J Endod 2006;32:331-333. DOI |
7 | Giannelli M, Chellini F, Margheri M, Tonelli P, Tani A. Effect of chlorhexidine digluconate on different cell types: a molecular and ultrastructural investigation. Toxicol In Vitro 2008;22:308-317. DOI |
8 | Bonacorsi C, Raddi MS, Carlos IZ. Cytotoxicity of chlorhexidine digluconate to murine macrophages and its effect on hydrogen peroxide and nitric oxide induction. Braz J Med Biol Res 2004;37:207-212. DOI |
9 | Sedlock DM, Bailey DM. Microbicidal activity of octenidine hydrochloride, a new alkanediylbis[pyridine] germicidal agent. Antimicrob Agents Chemother 1985;28:786-790. DOI |
10 | Slee AM, O'Connor JR. In vitro antiplaque activity of octenidine dihydrochloride (WIN 41464-2) against preformed plaques of selected oral plaque-forming microorganisms. Antimicrob Agents Chemother 1983;23:379-384. DOI |
11 | Tirali RE, Bodur H, Sipahi B, Sungurtekin E. Evaluation of the antimicrobial activities of chlorhexidine gluconate, sodium hypochlorite and octenidine hydrochloride in vitro. Aust Endod J 2013;39:15-18. DOI |
12 | Murad CF, Sassone LM, Faveri M, Hirata R Jr, Figueiredo L, Feres M. Microbial diversity in persistent root canal infections investigated by checkerboard DNA-DNA hybridization. J Endod 2014;40:899-906. DOI |
13 | Wikipedia. Staphylococcus epidermidis [Internet]. [place unknown]: Wikipedia; 2016 [updated 2018 Aug 5]. Available from: https://en.wikipedia.org/wiki/Staphylococcus_epidermidis. |
14 | Haapasalo M, Orstavik D. In vitro infection and disinfection of dentinal tubules. J Dent Res 1987;66:1375-1379. DOI |
15 | Patters MR, Anerud K, Trummel CL, Kornman KS, Nalbandian J, Robertson PB. Inhibition of plaque formation in humans by octenidine mouthrinse. J Periodontal Res 1983;18:212-219. DOI |
16 | Ghivari SB, Bhattacharya H, Bhat KG, Pujar MA. Antimicrobial activity of root canal irrigants against biofilm forming pathogens: an in vitro study. J Conserv Dent 2017;20:147-151. DOI |
17 | Shern RJ, Monell-Torrens E, Kingman A. Effect of two recently developed antiseptics on dental plaque and caries in rats. Caries Res 1985;19:458-465. DOI |
18 | Hubner NO, Siebert J, Kramer A. Octenidine dihydrochloride, a modern antiseptic for skin, mucous membranes and wounds. Skin Pharmacol Physiol 2010;23:244-258. DOI |
19 | Kapur I, Aggarwal A, Makkar S, Pasricha S. Comparative evaluation of octenidine hydrochloride and chlorhexidine as antibacterial root canal irrigant. Indian J Oral Sci 2015;6:10-13. DOI |
20 | Tirali RE, Turan Y, Akal N, Karahan ZC. In vitro antimicrobial activity of several concentrations of NaOCl and Octenisept in elimination of endodontic pathogens. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;108:e117-e120. |
21 | Ohara P, Torabinejad M, Kettering JD. Antibacterial effects of various endodontic medicaments on selected anaerobic bacteria. J Endod 1993;19:498-500. DOI |
22 | Sundqvist G. Taxonomy, ecology, and pathogenicity of the root canal flora. Oral Surg Oral Med Oral Pathol 1994;78:522-530. DOI |
23 | Yoshida M, Fukushima H, Yamamoto K, Ogawa K, Toda T, Sagawa H. Correlation between clinical symptoms and microorganisms isolated from root canals of teeth with periapical pathosis. J Endod 1987;13:24-28. DOI |
24 | Yesilsoy C, Whitaker E, Cleveland D, Phillips E, Trope M. Antimicrobial and toxic effects of established and potential root canal irrigants. J Endod 1995;21:513-515. DOI |
25 | Bufflier P, Suchett-Kaye G, Morrier JJ, Benay G, Decoret D, Bonin P, Renard F, Barsotti O. In vitro evaluation of the antibacterial effects of intracanal micro plasma system treatment. J Endod 1997;23:28-31. DOI |
26 | Harrison JW. Irrigation of the root canal system. Dent Clin North Am 1984;28:797-808. |
27 | Paster BJ, Olsen I, Aas JA, Dewhirst FE. The breadth of bacterial diversity in the human periodontal pocket and other oral sites. Periodontol 2000 2006;42:80-87. DOI |
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