Browse > Article
http://dx.doi.org/10.5395/JKACD.2010.35.3.198

A CLINICAL EVALUATION OF SAFETY OF AN OFFICE BLEACHING GEL CONTAINING 30% HYDROGEN PEROXIDE  

Kim, Sin-Young (Department of Conservative Dentistry, Seoul St. Mary's Hospital, Catholic University of Korea)
Park, Je-Uk (Department of Oral and Maxillofacial Surgery, Seoul St. Mary's Hospital, Catholic University of Korea)
Kim, Chang-Hyen (Department of Oral and Maxillofacial Surgery, Seoul St. Mary's Hospital, Catholic University of Korea)
Yang, Sung-Eun (Department of Conservative Dentistry, Seoul St. Mary's Hospital, Catholic University of Korea)
Publication Information
Restorative Dentistry and Endodontics / v.35, no.3, 2010 , pp. 198-210 More about this Journal
Abstract
This study evaluated the safety of an office bleaching gel (RemeWhite, Remedent Inc., Deurle, Belgium) containing 30% hydrogen peroxide. 37 volunteers were received office bleaching with the RemeWhite for 3 times at one visit, total 2 visits. As control group, the same gel in which hydrogen peroxide was not included was applied to 34 volunteers with the same protocol. There was no difference between experimental group and control group using electric pulp test. In the result of gingival inflammation index and tooth sensitivity test, there was mild pain response in experimental group but it disappeared as time went by. Therefore, safety of the office bleaching gel containing 30% hydrogen peroxide was confirmed.
Keywords
Office bleaching gel; Safety; Hydrogen peroxide; Clinical study;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
연도 인용수 순위
1 박종현, 신혜진, 박덕영, 박세희, 김진우, 조경모. 미백보조광 조사가 치아미백의 효과에 미치는 영향. 대한치과보존학회지 34:95-102, 2009.   DOI
2 Zach L, Cohen G. Pulp response to externally applied heat. Oral Surg Oral Med Oral Pathol 19:515-30, 1965.   DOI   ScienceOn
3 Al Shethri S, Matis BA, Cochran MA, Zekonis R, Stropes M. A Clinical evaluation of two in-office bleaching products. Oper Dent 28:488-95, 2003.
4 Zekonis R, Matis BA, Cochran MA, Al Shetri SE, Eckert GJ, Carlson TJ. Clinical evaluation of in-office and at-home bleaching treatments. Oper Dent 28:114-21, 2003.
5 Martin JH, Bishop JC, Guentherman RH, Dorman HL. Cellular response of gingiva to prolonged application of dilute hyorogen peroxide. J Periodontol 39:208-10, 1968.   DOI
6 김신영, 박재억, 김창현, 양성은. 30% 과산화수소를 함유한 전 문가 미백제의 효용성 평가. 대한치과보존학회지 35:40-50, 2010.
7 박은숙, 성소래, 홍성태, 김지은, 이소영, 황수연, 이신재, 진보 형, 손호현, 조병훈. 2.9% 과산화수소를 함유한 부착형 미백제 의 임상적 효능과 안정성에 관한 연구. 대한치과보존학회지 31:269-281, 2006.
8 Gurgan S, Cakir FY, Yazici E. Different light-activated in-office bleaching systems: a clinical evaluation. Lasers Med Sci, Epub, 2009.
9 Munro IC, Williams GM, Heymann HO, Kroes R. Tooth whitening products and the risk of oral cancer. Food Chem Toxicol 44:301-15, 2006.   DOI   ScienceOn
10 Naik S, Tredwin CJ, Scully C. Hydrogen peroxide tooth-whitening (bleaching) : review of safety in relation to possible carcinogenesis. Oral Oncol. 42:668-74, 2006.   DOI   ScienceOn
11 Mahony C, Felter SP, McMillan DA. An exposurebased risk assessment approach to confirm the safety of hydrogen peroxide for use in home bleaching. Regul Toxicol Pharmacol 44;75-82, 2006.   DOI   ScienceOn
12 Hsie AW, Recio L, Katz DS, Lee CQ, Wagner M, Schenley RL. Evidence for reactive oxygen species inducing mutations in mammalian cells. Proc Natl Acad Sci USA 83:9616-20, 1986.   DOI   ScienceOn
13 Weitzman SA Weitberg AB, Stossel TP, Schwartz J, Shklar G. Effects of hydrogen peroxide on oral carcinogenesis in hamsters. J Periodontol 44:685-8.1986.
14 Thitinanthapan W, Satamanont P, Vongsavan N. In vitro penetration of the pulp chamber by three brands of carbamide peroxide. J Esthet Dent 11:259-64, 1999.   DOI
15 Schulte JR, Morrissette DB, Gasior EJ, Czajewski MV. The effects of bleaching application time on the dental pulp. J Am Dent Assoc 125:1330-5, 1994.   DOI
16 Gokay O, Yilmaz F, Akin S, Tuncbilek M, Ertan R. Penetration of the pulp chamber by bleaching agents in teeth restored with various restorative materials. J Endod 26:92-4, 2000.   DOI   ScienceOn
17 Tredwin CJ, Naik S, Lewis NJ, Scully C. Hydrogen peroxide tooth-whitening (bleaching) products : review of adverse effects and safety issues. Br Dent J 8;200:371-6, 2006.   DOI   ScienceOn
18 Leonard RH, Haywood VB, Phillips C. Risk factors for developing tooth sensitivity and gingival irritation associated with nightguard vital bleaching. Quintessence Int 28:527-34, 1997.
19 Tam L. Clinical trial of three 10% carbamide peroxide bleaching products. J Can Dent Assoc 65:201-5, 1999.
20 Cohen SC. Human pulpal response to bleaching procedures on vital teeth. J Endod 5:134-8, 1979.   DOI   ScienceOn
21 Nathanson D, Parra C. Bleaching vital teeth-a review and clinical study. Compendium 8: 490-2, 494, 496-7, 1987.