Browse > Article
http://dx.doi.org/10.4047/jap.2013.5.1.51

Relationship of tooth mortality and implant treatment in Type 2 diabetes mellitus patients in Korean adults  

Jung, Hyun-Yub (Department of Periodontics, College of Dentistry, Kyungpook National University)
Kim, Yong-Gun (Department of Periodontics, College of Dentistry, Kyungpook National University)
Jin, Myoung-Uk (Department of Conservative Dentistry, College of Dentistry, Kyungpook National University)
Cho, Jin-Hyun (Department of Prosthodontics, College of Dentistry, Kyungpook National University)
Lee, Jae-Mok (Department of Periodontics, College of Dentistry, Kyungpook National University)
Publication Information
The Journal of Advanced Prosthodontics / v.5, no.1, 2013 , pp. 51-57 More about this Journal
Abstract
PURPOSE. The purpose of this study was to to analyze the effect of Type 2 diabetes on tooth mortality, implant treatment and prosthetic status. MATERIALS AND METHODS. 275 Type 2 diabetics and 300 non-diabetics, aged 40-80 years were selected for analysis. The assessment of number of teeth, missing teeth, fixed prostheses (bridge pontics), implants using panoramic radiographs and dental records were carried out. RESULTS. Diabetes mellitus (DM) patients had a higher number of missing teeth (P<.05) and placed implants (P=.074), age (P<.05), male gender percentage (P=.042), smoker percentage (P<.05) than non-DM patients. In univariate analysis, the patients in older group showed significantly higher number of tooth loss rate at the first dental examination than the patients in younger group. Tooth loss rate of smokers did not show higher value than that of non-smokers. When multiple variables including DM, age, smoking, gender were considered together, diabetics and older group patients showed significantly higher tooth loss rate at the first dental examination than non-diabetics and younger group patients, respectively. Smokers and male group did not show a significant difference than nonsmokers and female group, respectively. CONCLUSION. Tooth mortality and implant treatment rate were significantly higher in the DM group as indicated by univariate and multivariate logistic regression analysis. Old age groups showed significantly higher odds ratios and tooth loss rate. As diabetics showed the higher tooth loss rate than non-diabetics, diabetics also had more implant restorations than non-diabetics.
Keywords
Diabetic mellitus; Tooth loss; Implant restoration; Prosthetic status;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Eickholz P, Kaltschmitt J, Berbig J, Reitmeir P, Pretzl B. Tooth loss after active periodontal therapy. 1: patient-related factors for risk, prognosis, and quality of outcome. J Clin Periodontol 2008;35:165-74.   DOI   ScienceOn
2 Field EA, Longman LP, Bucknall R, Kaye SB, Higham SM, Edgar WM. The establishment of a xerostomia clinic: a prospective study. Br J Oral Maxillofac Surg 1997;35:96-103.   DOI   ScienceOn
3 Kadir T, Pisiriciler R, Akyüz S, Yarat A, Emekli N, Ipbüker A. Mycological and cytological examination of oral candidal carriage in diabetic patients and non-diabetic control subjects: thorough analysis of local aetiologic and systemic factors. J Oral Rehabil 2002;29:452-7.   DOI   ScienceOn
4 Petrou-Amerikanou C, Markopoulos AK, Belazi M, Karamitsos D, Papanayotou P. Prevalence of oral lichen planus in diabetes mellitus according to the type of diabetes. Oral Dis 1998;4:37-40.
5 Lorini R, Scaramuzza A, Vitali L, d'Annunzio G, Avanzini MA, De Giacomo C, Severi F. Clinical aspects of coeliac disease in children with insulin-dependent diabetes mellitus. J Pediatr Endocrinol Metab 1996;9:101-11.
6 Gug genheimer J, Moore PA, Rossie K, Myers D, Mongelluzzo MB, Block HM, Weyant R, Orchard T. Insulin-dependent diabetes mellitus and oral soft tissue pathologies: II. Prevalence and characteristics of Candida and Candidal lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89:570-6.   DOI   ScienceOn
7 Hill LV, Tan MH, Pereira LH, Embil JA. Association of oral candidiasis with diabetic control. J Clin Pathol 1989;42:502-5.   DOI
8 Kim JB, Jung MH, Cho JY, Park JW, Suh JY, Lee JM. The influence of type 2 diabetes mellitus on the expression of inflammatory mediators and tissue inhibitor of metalloproteinases- 2 in human chronic periodontitis. J Periodontal Implant Sci 2011;41:109-16.   DOI   ScienceOn
9 Ryan ME, Carnu O, Kamer A. The influence of diabetes on the periodontal tissues. J Am Dent Assoc 2003;134: 34S-40S.   DOI   ScienceOn
10 Nishimura F, Iwamoto Y, Soga Y. The periodontal host response with diabetes. Periodontol 2000 2007;43:245-53.   DOI   ScienceOn
11 McMullen JA, Van Dyke TE, Horoszewicz HU, Genco RJ. Neutrophil chemotaxis in individuals with advanced periodontal disease and a genetic predisposition to diabetes mellitus. J Periodontol 1981;52:167-73.   DOI
12 Tan JS, Anderson JL, Watanakunakorn C, Phair JP. Neutrophil dysfunction in diabetes mellitus. J Lab Clin Med 1975;85:26-33.
13 Um YJ, Jung UW, Kim CS, Bak EJ, Cha JH, Yoo YJ, Choi SH. The influence of diabetes mellitus on periodontal tissues: a pilot study. J Periodontal Implant Sci 2010;40:49-55.   DOI   ScienceOn
14 Davies JE. Understanding peri-implant endosseous healing. J Dent Educ 2003;67:932-49.
15 Genco RJ. Current view of risk factors for periodontal diseases. J Periodontol 1996;67:1041-9.   DOI
16 Southerland JH, Taylor GW, Mos s K, Beck JD, Offenbacher S. Commonality in chronic inflammatory diseases: periodontitis, diabetes, and coronary artery disease. Periodontol 2000 2006; 40:130-43.   DOI   ScienceOn
17 Scherp HW. Current concepts in periodontal disease research: epidemiological contributions. J Am Dent Assoc 1964;68:667-75.   DOI
18 Löe H. Periodontal disease. The sixth complication of diabetes mellitus. Diabetes Care 1993;16:329-34.   DOI
19 Hasegawa H, Ozawa S, Hashimoto K, Takeichi T, Ogawa T. Type 2 diabetes impairs implant osseointegration capacity in rats. Int J Oral Maxillofac Implants 2008;23:237-46.
20 Ferreira SD, Silva GL, Cortelli JR, Costa JE, Costa FO. Prevalence and risk variables for peri-implant disease in Brazilian subjects. J Clin Periodontol 2006;33:929-35.   DOI   ScienceOn
21 Olson JW, Shernoff AF, Tarlow JL, Colwell JA, Scheetz JP, Bingham SF. Dental endosseous implant assessments in a type 2 diabetic population: a prospective study. Int J Oral Maxillofac Implants 2000;15:811-8.
22 Peled M, Ardekian L, Tagger-Green N, Gutmacher Z, Machtei EE. Dental implants in patients with type 2 diabetes mellitus: a clinical study. Implant Dent 2003;12:116-22.   DOI   ScienceOn
23 Horning GM, Hatch CL, Cohen ME. Risk indicators for periodontitis in a military treatment population. J Periodontol 1992;63:297-302.   DOI
24 Emrich LJ, Shlossman M, Genco RJ. Periodontal disease in non-insulin-dependent diabetes mellitus. J Periodontol 1991;62:123-31.   DOI
25 Tervonen T, Oliver RC. Long-term control of diabetes mellitus and periodontitis. J Clin Periodontol 1993;20: 431-5.   DOI   ScienceOn
26 Campus G, Salem A, Uzzau S, Baldoni E, Tonolo G. Diabetes and periodontal disease: a case-control study. J Periodontol 2005;76:418-25.   DOI   ScienceOn
27 Faggion CM Jr, Petersilka G, Lange DE, Gerss J, Flemmig TF. Prognostic model for tooth survival in patients treated for periodontitis. J Clin Periodontol 2007;34:226-31.   DOI   ScienceOn
28 Bacić M, Plancak D, Granić M. CPITN assessment of periodontal disease in diabetic patients. J Periodontol 1988;59: 816-22.   DOI
29 Ebersole JL, Holt SC, Hansard R, Novak MJ. Microbiologic and immunologic characteristics of periodontal disease in Hispanic americans with type 2 diabetes. J Periodontol 2008;79:637-46.   DOI   ScienceOn
30 Soskolne WA. Epidemiological and clinical aspects of periodontal diseases in diabetics. Ann Periodontol 1998;3:3-12.   DOI   ScienceOn
31 Taylor GW. Bidirectional interrelationships between diabetes and periodontal diseases: an epidemiologic perspective. Ann Periodontol 2001;6:99-112.   DOI   ScienceOn
32 Taylor GW, Borgnakke WS. Periodontal disease: associations with diabetes, glycemic control and complications. Oral Dis 2008;14:191-203.   DOI   ScienceOn
33 Mealey BL, Ocampo GL. Diabetes mellitus and periodontal disease. Periodontol 2000 2007;44:127-53.   DOI   ScienceOn
34 Grossi SG, Skrepcinski FB, DeCaro T, Robertson DC, Ho AW, Dunford RG, Genco RJ. Treatment of periodontal disease in diabetics reduces glycated hemoglobin. J Periodontol 1997;68:713-9.   DOI   ScienceOn
35 Grossi SG, Skrepcinski FB, DeCaro T, Zambon JJ, Cummins D, Genco RJ. Response to periodontal therapy in diabetics and smokers. J Periodontol 1996;67:1094-102.   DOI   ScienceOn
36 Rodrigues DC, Taba MJ, Novaes AB, Souza SL, Grisi MF. Effect of non-surgical periodontal therapy on glycemic control in patients with type 2 diabetes mellitus. J Periodontol 2003;74:1361-7.   DOI   ScienceOn
37 Kiran M, Arpak N, Unsal E, Erdoğan MF. The effect of improved periodontal health on metabolic control in type 2 diabetes mellitus. J Clin Periodontol 2005;32:266-72.   DOI   ScienceOn
38 Taylor GW, Burt BA, Becker MP, Genco RJ, Shlossman M, Knowler WC, Pettitt DJ. Severe periodontitis and risk for poor glycemic control in patients with non-insulin-dependent diabetes mellitus. J Periodontol 1996;67:1085-93.   DOI   ScienceOn
39 Grossi SG, Skrepcinski FB, DeCaro T, Robertson DC, Ho AW, Dunford RG, Genco RJ. Treatment of periodontal disease in diabetics reduces glycated hemoglobin. J Periodontol 1997;68:713-9.   DOI   ScienceOn
40 Cochran DL. Inflammation and bone loss in periodontal disease. J Periodontol 2008;79:1569-76.   DOI   ScienceOn
41 Tawil G, Younan R, Azar P, Sleilati G. Conventional and advanced implant treatment in the type II diabetic patient: surgical protocol and long-term clinical results. Int J Oral Maxillofac Implants 2008;23:744-52.
42 Michaeli E, Weinberg I, Nahlieli O. Dental implants in the diabetic patient: systemic and rehabilitative considerations. Quintessence Int 2009;40:639-45.
43 Aitken S, Birek P, Kulkarni GV, Lee WL, McCulloch CA. Serial doxycycline and metronidazole in prevention of recurrent periodontitis in high-risk patients. J Periodontol 1992;63:87-92.   DOI
44 Thorstensson H, Hugoson A. Periodontal disease experience in adult long-duration insulin-dependent diabetics. J Clin Periodontol 1993;20:352-8.   DOI   ScienceOn