Effect and mechanism of chitosan-based nano-controlled release system on the promotion of cell cycle progression gene expression
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Lee, Won Joong
(Department of Biomaterials & Prosthodontics, Kyung Hee University Hospital at Gangdong, School of Dentistry, Kyung Hee University)
Park, Kwang Man (Department of Dentistry, Graduate School, Kyung Hee University) Lee, sungbok Richard (Department of Biomaterials & Prosthodontics, Kyung Hee University Hospital at Gangdong, School of Dentistry, Kyung Hee University) Hwang, Yu Jeong (Department of Biomaterials & Prosthodontics, Kyung Hee University Hospital at Gangdong, School of Dentistry, Kyung Hee University) Lee, Suk Won (Department of Biomaterials & Prosthodontics, Kyung Hee University Hospital at Gangdong, School of Dentistry, Kyung Hee University) |
1 | Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G. E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop. Mol Cell Biol 2007;27:65-78. DOI |
2 | Gaubatz S, Lindeman GJ, Ishida S, Jakoi L, Nevins JR, Livingston DM, Rempel RE. E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control. Mol Cell 2000;6:729-35. DOI |
3 | Moyle MW, Kim T, Hattersley N, Espeut J, Cheerambathur DK, Oegema K, Desai A. A Bub1-Mad1 interaction targets the Mad1-Mad2 complex to unattached kinetochores to initiate the spindle checkpoint. J Cell Biol 2014;204:647-57. DOI |
4 | Dou Z, Prifti DK, Gui P, Liu X, Elowe S, Yao X. Recent progress on the localization of the spindle assembly checkpoint machinery to kinetochores. Cells 2019;8:278. DOI |
5 | Restuccia A, Yang F, Chen C, Lu L, Dai W. Mps1 is SUMO-modified during the cell cycle. Oncotarget 2016;7:3158-70. DOI |
6 | Ying H, Furuya F, Zhao L, Araki O, West BL, Hanover JA, Willingham MC, Cheng SY. Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression. J Clin Invest 2006;116:2972-84. DOI |
7 | Xiao X, Liu H, Li X. Orlistat treatment induces apoptosis and arrests cell cycle in HSC-3 oral cancer cells. Microb Pathog 2017;112:15-9. DOI |
8 | Roskoski R Jr. ERK1/2 MAP kinases: structure, function, and regulation. Pharmacol Res 2012;66:105-43. DOI |
9 | Dai JL, Bansal RK, Kern SE. G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: phenotypes reversed by a tumorigenic mutation. Proc Natl Acad Sci USA 1999;96:1427-32. DOI |
10 | Meloche S, Pouyssegur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 2007;26:3227-39. DOI |
11 | Lee KH, Ben Amara H, Lee SC, Leesungbok R, Chung MA, Koo KT, Lee SW. Chemical regeneration of wound defects: relevance to the canine palatal mucosa and cell cycle up-regulation in human gingival fibroblasts. Tissue Eng Regen Med 2019;16:675-84. DOI |
12 | Dirks PB, Rutka JT. Current concepts in neuro-oncology: the cell cycle-a review. Neurosurgery 1997;40:1000-15. DOI |
13 | Vermeulen K, Van Bockstaele DR, Berneman ZN. The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. Cell Prolif 2003;36:131-49. DOI |
14 | Zhang W, Liu HT. MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res 2002;12:9-18. DOI |
15 | Park KM, Lee HJ, Koo KT, Ben Amara H, Leesungbok R, Noh K, Lee SC, Lee SW. Oral soft tissue regeneration using nano controlled system inducing sequential release of trichloroacetic acid and epidermal growth factor. Tissue Eng Regen Med 2020;17:91-103. DOI |
16 | Ji P, Agrawal S, Diederichs S, Baumer N, Becker A, Cauvet T, Kowski S, Beger C, Welte K, Berdel WE, Serve H, Muller-Tidow C. Cyclin A1, the alternative A-type cyclin, contributes to G1/S cell cycle progression in somatic cells. Oncogene 2005;24:2739-44. DOI |
17 | Li YL, Wang J, Zhang CY, Shen YQ, Wang HM, Ding L, Gu YC, Lou JT, Zhao XT, Ma ZL, Jin YX. MiR-146a-5p inhibits cell proliferation and cell cycle progression in NSCLC cell lines by targeting CCND1 and CCND2. Oncotarget 2016;7:59287-98. DOI |
18 | Das E, Jana NR, Bhattacharyya NP. MicroRNA-124 targets CCNA2 and regulates cell cycle in STHdhQ111/HdhQ111 cells. Biochem Biophys Res Commun 2013;437:217-24. DOI |
19 | Zhou JJ, Cheng D, He XY, Meng Z, Li WZ, Chen RF. Knockdown of Hotair suppresses proliferation and cell cycle progression in hepatocellular carcinoma cell by downregulating CCND1 expression. Mol Med Rep 2017;16:4980-6. DOI |
20 | Thurlings I, de Bruin A. E2F transcription factors control the roller coaster ride of cell cycle gene expression. Methods Mol Biol 2016;1342:71-88. DOI |
21 | Shaltiel IA, Krenning L, Bruinsma W, Medema RH. The same, only different - DNA damage checkpoints and their reversal throughout the cell cycle. J Cell Sci 2015;128:607-20. DOI |
22 | Bi W, Xiao JC, Liu RJ, Zhou LY, Zhang S, Yang M, Zhang PF. Identification of a 3,3-difluorinated tetrahydropyridinol compound as a novel antitumor agent for hepatocellular carcinoma acting via cell cycle arrest through disturbing CDK7-mediated phosphorylation of Cdc2. Invest New Drugs 2020;38:287-98. DOI |
23 | Vairapandi M, Balliet AG, Hoffman B, Liebermann DA. GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress. J Cell Physiol 2002;192:327-38. DOI |
24 | Chen Y, Li Z, Dong Z, Beebe J, Yang K, Fu L, Zhang JT. 14-3-3σ contributes to radioresistance by regulating DNA repair and cell cycle via PARP1 and CHK2. Mol Cancer Res 2017;15:418-28. DOI |
25 | Rainey MD, Quachthithu H, Gaboriau D, Santocanale C. DNA replication dynamics and cellular responses to ATP competitive CDC7 kinase inhibitors. ACS Chem Biol 2017;12:1893-902. DOI |
26 | Cheng S, Castillo V, Sliva D. CDC20 associated with cancer metastasis and novel mushroomderived CDC20 inhibitors with antimetastatic activity. Int J Oncol 2019;54:2250-6. |
27 | Rosenberg E, Demopoulos RI, Zeleniuch-Jacquotte A, Yee H, Sorich J, Speyer JL, Newcomb EW. Expression of cell cycle regulators p57(KIP2), cyclin D1, and cyclin E in epithelial ovarian tumors and survival. Hum Pathol 2001;32:808-13. DOI |
28 | Zhao H, Watkins JL, Piwnica-Worms H. Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints. Proc Natl Acad Sci USA 2002;99:14795-800. DOI |
29 | Sheu YJ, Stillman B. The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4. Nature 2010;463:113-7. DOI |
30 | Sheu YJ, Stillman B. Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol Cell 2006;24:101-13. DOI |
31 | Liang KL, Paredes R, Carmody R, Eyers PA, Meyer S, McCarthy TV, Keeshan K. Human TRIB2 oscillates during the cell cycle and promotes ubiquitination and degradation of CDC25C. Int J Mol Sci 2016;17:1378. DOI |
32 | Zhi T, Jiang K, Xu X, Yu T, Wu W, Nie E, Zhou X, Jin X, Zhang J, Wang Y, Liu N. MicroRNA-520d-5p inhibits human glioma cell proliferation and induces cell cycle arrest by directly targeting PTTG1. Am J Transl Res 2017;9:4872-87. |
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