Browse > Article
http://dx.doi.org/10.5392/JKCA.2022.22.07.652

Regarding the Problem of Clinical Application of New Medical Technology in the Field of Spine Surgery Found through the Case of Intradiscal Electrothermal Therapy  

Hong, Youngki (청주대학교 스포츠건강재활 전공)
Publication Information
The Journal of the Korea Contents Association / v.22, no.7, 2022 , pp. 652-662 More about this Journal
Abstract
Currently, in the field of spinal surgery around the world, various new technologies have been rapidly developed and applied to patients. The author believes that it is necessary to discuss whether these new technologies are being fully reviewed for efficacy and safety before being applied to patients. To consider this issue, the author analyzed the basic research data and clinical application process of the intradiscal electrothermal therapy, which was developed as a new technology for discogenic pain disease in the 2000s and has been widely used worldwide. As a result, it was found that this procedure has been performed on patients in a state where there is insufficient base research on efficacy and safety. The author judges that this case reveals an essential problem related to the clinical operation of new medical technologies in the field of spine surgery. Therefore, the author believes that in order to minimize the side effects that new medical technology in the field of spinal surgery may have on patients, more full-fledged basic research and higher clinical acceptance standards should be established.
Keywords
Discogenic Pain; Intradiscal Electrothermal Therapy; New Medical Technology; Medical Ethics;
Citations & Related Records
연도 인용수 순위
  • Reference
1 S. G. Sin, "신약 임상시험의 과정 및 관련 지침," 대한임상약리학회: 학술대회논문집, pp.30-41, 2000.
2 J. S. Saal and J. A. Saal, "Thermal characteristics of lumbar disc: Evaluation of a novel approach to targeted intradiscal thermal therapy," Presented at the 13th annual meeting of the North American Spine Society. San Francisco, California, October 28-31, 1998.
3 F. S. Letcher and S. Goldring, "The effect of radiofrequency current and heat on peripheral nerve action potential in the cat," Journal of Neurosurgery, Vol.29, No.1, pp.42-47, 1968.   DOI
4 O. L. Osti, B. Vernon-Roberts, and R. D. Fraser, "Anulus tears and intervertebral disc degeneration. An experimental study using an animal model. 1990 Volvo Award in experimental studies," Spine, Vol.15, pp.762-767, 1990.
5 K. Hayashi, G. Thabit III, A. C. Vailas, J. J. Bogdanske, A. J. Cooley, and M. D. Markel, "The effect of nonablative laser energy on joint capsular properties: An in vitro histologic and biochemical study using a rabbit model," The American Journal of Sports Medicine, Vol.24, No.5, pp.640-646, 1996.   DOI
6 B. Peng, W. Wu, S. Hou, P. Li, C. Zhang, and Y. Yang, "The pathogenesis of discogenic low back pain," Journal of Bone and Joint Surgery, Vol.87, No.1, pp.62-67, 2005.
7 J. S. Saal and J. A. Saal, "Management of chronic discogenic low back pain with a thermal intradiscal catheter: a preliminary report," Spine, Vol.25, No.3, pp.382-388, 2000.   DOI
8 N. Bogduk, W. Tynan, and A. S. Wilson, "The nerve supply to the human lumbar intervertebral discs," Journal of anatomy, Vol.131, No.1, pp.39-56, 1981.
9 K. Takahashi, Y. Aoki, and S. Ohtori, "Resolving discogenic pain," European. Spine Journal, Vol.17, No.4, pp.428-431, 2008.   DOI
10 A. C. Schwarzer, C. N. Aprill, R. Derby, J. Fortin, G. Kine, and N. Bogduk, "The prevalence and clinical features of internal disc disruption in patients with chronic low back pain," Spine, Vol.20, No.17, pp.1878-1883, 1995.   DOI
11 안민지, 윤서라, 류수라. "경추부 디스크 내 고주파열 치료술 후 발생한 연하장애: 증례 보고," 대한연하장애학회지, 제10권, 제2호, pp.167-171, 2020.   DOI
12 D. K. Sokol, "'First do no harm' revisited," British Medical Journal, Vol.347, 2013.
13 W. H. S. Johns, Hippocrates, Volume I: Ancient Medicine, Loeb Classical Library, 1923.
14 W. H. S. Johns, Hippocrates, Volume VII: Epidemics 2 and 4-7, Loeb Classical Library, 1923.
15 E. J. Emanuel, "The solution to drug prices," New York Times, Vol.9, 2015.
16 http://www.healthmedia.co.kr/news/articleView.html?idxno=50978
17 F. S. Kleinstueck, S. Frank, C. J. Diederich, H. W. Nau, M. C. Puttlitz, J. A. Smith, D. S. Bradford, and J. C. Lotz, "Temperature and thermal dose distributions during intradiscal electrothermal therapy in the cadaveric lumbar spine," Spine, Vol.28, No.15, pp.1700-1708, 2003.   DOI
18 B. J. C. Freeman, R. M. Walters, R. J. Moore, and R. D. Fraser, "Does intradiscal electrothermal therapy denervate and repair experimentally induced posterolateral annular tears in an animal model?," Spine, Vol.28, No.23, pp.2602-2608, 2003.   DOI
19 B. J. C. Freeman, R. D. Fraser, C. M. J. Cain, D. J. Hall, and D. C. L. Chapple, "A randomized, double-blind, controlled trial: intradiscal electrothermal therapy versus placebo for the treatment of chronic discogenic low back pain," Spine, Vol.30, No.21, pp.2369-2377, 2005.   DOI
20 D. Appleby, G. Andersson, and M. Totta, "Meta-analysis of the efficacy and safety of intradiscal electrothermal therapy (IDET)," Pain Medicine, Vol.7, No.4, pp.308-316, 2006.   DOI
21 X. X. Song, S. Shi, Z. Guo, X. F. Li, and B. W. Yu, "Estrogen receptors involvement in intervertebral discogenic pain of the elderly women: colocalization and correlation with the expression of Substance P in nucleus pulposus," Oncotarget, Vol.8, No.24, p.38136, 2017.   DOI
22 K. J. Pauza, S. Howell, P. Dreyfuss, J. H. Peloza, K. Dawson, and N. Bogduk, "A randomized, placebo-controlled trial of intradiscal electrothermal therapy for the treatment of discogenic low back pain," Spine Journal, Vol.4, No.1, pp.27-35, 2004.   DOI
23 F. S. Kleinstueck, S. Frank, C. J. Diederich, H. W. Nau, M. C. Puttlitz, J. A. Smith, and S. David, "Acute biomechanical and histological effects of intradiscal electrothermal therapy on human lumbar discs," Spine, Vol.26, No.20, pp.2198-2207, 2001.   DOI
24 M. S. Wall, X. H. Deng, P. A. Torzilli, S. B. Doty, S. J. O'Brien, and R. F. Warren, "Thermal modification of collagen," Journal of Shoulder and Elbow Surgery, Vol.8, No.4, pp.339-344, 1999.   DOI
25 R. Derby, S. H. Lee, B. J. Kim, Y. Chen, C. Aprill, and N. Bogduk, "Pressure-controlled lumbar discography in volunteers without low back symptoms," Pain Medicine, Vol.6, No.3, pp.213-221, 2005.   DOI
26 K. Hayashi, G. Thabit III, J. J. Bogdanske, L. N. Mascio, and M. D. Markel, "The effect of nonablative laser energy on the ultrastructure of joint capsular collagen," The Journal of Arthroscopic & Related Surgery, Vol.12, No.4, pp.474-481, 1996.   DOI