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http://dx.doi.org/10.5392/JKCA.2019.19.06.461

Importance of Target Blood Pressure Management in Diabetic Kidney Disease  

Kim, Hee Sung (단국대학교 의과대학 제일병원 진단검사의학과)
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The Journal of the Korea Contents Association / v.19, no.6, 2019 , pp. 461-470 More about this Journal
Abstract
In diabetes mellitus, renal disease is a common complication, characterized by increased urinary albumin excretion and reduced eGFR. According to KDIGO CKD stage classification, Korean characteristics were analyzed according to urinary albumin and eGFR using the National Health and Nutrition Examination Survey VI raw data. According to KDIGO classification, diabetic patients were classified as Low risk 72.0%, Moderate risk 19.3%, High risk 5.6% and Very high risk 3.0%. Low risk decreased from 74.7% to 52.2%, and moderate to very high risk increased from 25.4% to 47.8% as the duration of diabetes mellitus was prolonged. The risk factors were CKD stage 1 (HR 2.064) to stage 4 (HR 11.049), the highest risk of hypertension. The incidence of renal disease was elevated according to duration of hypertension and HR 0.42 of kidney disease was decreased in the group maintaining proper blood pressure. In the hypertensive patients, the group administered with target blood pressure had a reduction of the kidney disease by 42% than the group with the hypertension. Therefore, controlling and managing hypertension to target blood pressure is important for the prevention of kidney disease.
Keywords
Diabetes Complication; Risk Factors of Diabetic Kidney Disease; Hypertension;
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