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http://dx.doi.org/10.7742/jksr.2022.16.7.843

A Study on the Probability of Secondary Carcinogenesis during Gamma Knife Radiosurgery  

Joo-Ah, Lee (Department of Radiation Oncology, Catholic University, Incheon St.Mary's Hospital)
Gi-Hong, Kim (Yonsei University Health System, Severance Hospital Gamma Knife Center)
Publication Information
Journal of the Korean Society of Radiology / v.16, no.7, 2022 , pp. 843-849 More about this Journal
Abstract
In this study, the probability of secondary carcinogenesis was analyzed by measuring the exposure dose of surrounding normal organs during radiosurgery using a gamma knife. A pediatric phantom (Model 706-G, CIRS, USA) composed of human tissue-equivalent material was set to four tumor volumes of 0.25 cm3, 0.51 cm3, 1.01 cm3, and 2.03 cm3, and the average dose was 18.4 ± 3.4 Gy. After installing the Rando phantom on the table of the gamma knife surgical equipment, the OSLD nanoDot dosimeters were placed in the right eye, left eye, thyroid, thymus gland, right lung, and left lung to measure each exposure dose. The probability of cancer occurrence due to radiation exposure of surrounding normal organs during gamma knife radiosurgery for acoustic schwannoma disease was 4.08 cancers per 100,000 at a tumor volume of 2.03 cm3. This study is expected to be used as useful data in relation to stochastic effects in the future by studying the risk of secondary radiation exposure that can occur during stereotactic radiosurgery.
Keywords
Gamma Knife; OSLD nanoDot; Radiosurgery; Organs at risk; Target volume;
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Times Cited By KSCI : 7  (Citation Analysis)
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