Browse > Article
http://dx.doi.org/10.7742/jksr.2021.15.6.849

Development of the Radiological Range of Positron Emitting Radionuclides  

Jang, Dong-Gun (Department of Nuclear Medicine, Dongnam Institute of Radiological & Medical Sciences Cancer Center)
Lee, Sang-Ho (Department of Nuclear Medicine, Dongnam Institute of Radiological & Medical Sciences Cancer Center)
Publication Information
Journal of the Korean Society of Radiology / v.15, no.6, 2021 , pp. 849-853 More about this Journal
Abstract
PET images used in medical diagnoses are created using positron emitting radionuclides. The radiation used for imaging is generated at 0.511 MeV by p-annihilation. The CSDA range is the distance the particle radiation flew physically, and it is different from the range shown in PET images. This study proposes a novel method that uses radiological criteria to measure this range. The experiment was conducted by applying the MCNP6 simulation to positron emitting nuclides 18F, 11C, 13N, and 15O. Radiological criteria were based on the location of the p-annihilation event, which is also the image signal. Results showed the radiological range of positrons to be 2.3, 3.9, 5.0, and 7.9 mm for 18F, 11C, 13N, and 15O, respectively. The higher the positron energy, the larger its difference from the CSDA range. Positron emitting nuclide is being developed and studied as a nuclide for dosimetry or radiotherapy. Further research needs to be conducted into various positron ranges.
Keywords
Positron; Ranges; PET;
Citations & Related Records
연도 인용수 순위
  • Reference
1 L. Jodal, C. Le Loirec, C. Champion, "Positron range in PET imaging: non-conventional isotopes", Physics in Medicine and Biology, Vol. 59, No. 23, pp. 7419-7434, 2014. http://dx.doi.org/10.1088/0031-9155/59/23/7419   DOI
2 L. Jodal, "Beta emitters and radiation protection", Acta Oncologica, Vol. 48, No. 2, pp. 308-313, 2009. https://doi.org/10.1080/02841860802245163   DOI
3 D. Burdette, D. Albani, E. Chesi, N. Clinthorne, E. Cochran, K. Honscheid, S. S. Huh, H. Kagan, M. Knopp, C. Lacasta, M. Mikuz, P. Schmalbrock, A. Studen, P. Weilhammer, "A study of the effects of strong magnetic fields on the image resolution of PET scanners", In 2007 IEEE Nuclear Science Symposium Conference Record, Vol. 5, pp. 3383-3389, 2007. https://doi.org/10.1109/NSSMIC.2007.4436857   DOI
4 R. Laforest, X. Liu, "Image quality with non-standard nuclides in PET", Quarterly Journal of Nuclear Medicine and Molecular Imaging, Vol. 52, No. 2, pp. 151-158, 2008.
5 M. MacManus, U. Nestle, K. E. Rosenzweig, I. Carrio, C. Messa, O. Belohlavek, M. Danna, T. Inoue, E. Deniaud-Alexandre, S. Schipani, N. Watanabe, M. Dondi, B. Jeremic, "Use of PET and PET/CT for radiation therapy planning: IAEA expert report 2006-2007", Radiotherapy and Oncology, Vol. 91, No. 1, pp. 85-94, 2009. http://dx.doi.org/10.1016/j.radonc.2008.11.008   DOI
6 S. Mohammed, A. Trabelsi, "Determination of 18F Positron Range in PET Imaging using Monte Carlo Simulation - Geant4 Code", Indian Journal of Science and Technology, Vol. 14, No. 12, pp. 1-8, 2019. http://dx.doi.org/10.17485/ijst/2019/v12i14/143103   DOI
7 M. Conti, L. Eriksson, "Physics of pure and non-pure positron emitters for PET: a review and a discussion", EJNMMI physics, Vol. 3, No. 1, pp. 1-17, 2016. http://dx.doi.org/10.1186/s40658-016-0144-5   DOI
8 D. G. Jang, "Therapeutic radionuclides: beta radiation range", Journal of Instrumentation, Vol. 15, No. 8, T08002, 2020   DOI
9 B. Vaziri, H. Wu, A. P. Dhawan, P. Du, R. W. Howell, "MIRD pamphlet No. 25: MIRDcell V2.0 software tool for dosimetric analysis of biologic response of multicellular populations", Journal of Nuclear Medicine, Vol. 55, No. 9, pp. 1557-1564, 2014. http://dx.doi.org/10.2967/jnumed.113.131037   DOI
10 J. Coderre, Principles of Radiation Interactions, MIT Course Number 22.55J, MIT Open Course Ware, 2004.
11 C. S. Levin, E. J. Hoffman "Calculation of positron range and its effect on the fundamental limit of positron emission tomography system spatial resolution", Physics in Medicine and Biology, Vol. 44, No. 3, pp. 781-799, 1999. https://doi.org/10.1088/0031-9155/44/3/019   DOI