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http://dx.doi.org/10.7742/jksr.2020.14.2.97

The Radioprotection Effect of Aronia on Livers of Laboratory Rats Radiated to 6 MV X-ray of Linear Accelerator  

Lee, Jun-Haeng (Department of Radiology of Nambu University)
Publication Information
Journal of the Korean Society of Radiology / v.14, no.2, 2020 , pp. 97-104 More about this Journal
Abstract
This aimed at figuring out if there were the radioprotection effects of aronia on livers of laboratory rats radiated through serum test. For the objects of animal testing, one group consists of five male laboratory rats (weight 200~250 g), and the groups were set as follows: Group 1, normal; Group 2, 5 Gy radiated control group; and Group 3, 5 Gy radiated experiment group with aronia. Group 1(A) was prescribed with ordinary meal without radiation while the control group, Group 2(B) was prescribed with ordinary meal and radiation, and the experiment group, Group 3(C) was orally prescribed with aronia (daily oral dosage: 100 mg/kg/day) diluted with distilled water at the amount of 50 mg/kg/day twice a week, using oral zonde needle for rats for 14 days before being radiated, and then, radiation were made on them. For the study, using Linac (Linear Accelerator) 6 MV X-ray therapy device, rats were irradiated on their whole bodies once, and their blood was sampled for conducting five blood serum tests with regard to liver. For statistical analysis, ANOVA test was conducted. In conclusion, as a result of the analysis, it seemed that there were no the radioprotection effects of aronia on liver. However, it was confirmed statistically that ALB (P>0.05) showed no significance and that TP (P<0.05) showed significant differences. It is expected that there should be more tests in future.
Keywords
Linear Accelerator; Aronia; Radioprotection; Radiation;
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1 Radiation Biology Research Society, Radiation Biology, Chung ku Publisher 3th Edition pp. 294, 2015.
2 Y. H. Goo, H. S. Kim, Y. S. Park, Y. R. Kim, Radiation Biology, JMK, pp. 212-213, 2015.
3 Y. S. Park, H. T. Kim, S. J. Go, S. S. Lee, Radiation Biology, 2th Edition, JMK, pp. 316, 2019.
4 H. L. Kim, et. al., Human Anatomy, Medicine science publisher, pp. 192-195, 2011.
5 W. u. Xianli, G. u. Liwei, P. Ronald, M. Steve, "Characterization of anthocyanins and proanthocyanidins in some cultivars of Ribes, Aronia, and Sambucus and their antioxidant capacity," Journal of agricultural and food chemistry, Vol. 52 No. 26, pp. 7846-7902, 2004. http://dx.doi.org/10.1021/jf0486850   DOI
6 I. H. ko, J. D. Yeo, "The Protective Effect of Red Ginseng(RG) Extracts on the Liver of Mice by X-ray Irradiation and Medication of Paraquat Orally," Journal of the Korean Society of Radiology, Vol. 8, No. 3, pp. 157-145, 2014. http://dx.doi.org/10.7742/jksr.2014.8.3.137
7 A. W. Strigl, E. Leitner, W. Pfannhauser, "Qualitative und Quantitative Analyse der Anthocyane in Schwarzen Apfelbeeren (Aronia melanocarpa Michx. Ell.) mittels TLC, HPLC und UV/VIS-SpektrometrieQualitative and quantitative analyses of the anthocyans in black chokeberries (Aronia melanocarpa Michx. Ell.) by TLC, HPLC and UV/VIS-spectrometry," European food research and technology, Vol. 201 No. 3, pp. 266-268. 1995. http://dx.doi.org/10.1007/BF01193001
8 I. Jakobek, M. Drenjancevic, V. Jukic, M. Seruga, "Phenolic acids, flavonols, anthocyanins and antiradical activity of ''Nero'', ''Viking'', ''Galicianka'' and wild chokeberries," SCIENTIA HORTICULTURAE, Vol. 147 No. 12, pp. 56-63, 2012. http://dx.doi.org/10.1016/j.scienta.2012.09.006   DOI
9 https://news.v.daum.net/v/20161102173203870
10 S. I. Jang, J. H. Lee, "Radioprotective Effects of Blueberry on the Liver of Radiation Irradiated Rats," Journal of the Korean Society of Radiology, Vol. 7, No. 3, pp. 239-244, 2013. http://dx.doi.org/10.7742/jksr.2013.7.3.239   DOI