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http://dx.doi.org/10.7742/jksr.2019.13.2.247

Evaluation of Absorbed Dose According to the Gold Nanoparticle Density in Prostate Cancer Brachytherapy  

Lee, Deuk-Hee (Department of Radiation Oncology, Busan Paik Hospital, Inje University)
Kim, Jung-Hoon (Department of Radiological Science, College of Health Sciences, Catholic University of Pusan)
Publication Information
Journal of the Korean Society of Radiology / v.13, no.2, 2019 , pp. 247-252 More about this Journal
Abstract
This study was evaluated absorbed dose according to the gold nanoparticle density in prostate brachytherapy which was constantly occurred in Korean men. Absorbed dose evaluation was using MCNPX program which was applied Monte Carlo simulation. Source were applied $^{192}Ir$ which was temporary insertion source and $^{103}Pd$ which was permanently insertion source. And gold nanoparticle density was applied 0 mg, 7 mg, 18 mg and 30 mg. The prostate absorbed dose was increased in proportion to the density 2.95E-14 Gy/e to 4.42E-14 Gy/e in $^{192}Ir$ and showed the same tendency in $^{103}Pd$. And surrounding organ absorbed dose was inversely proportional to the density. Therefore using nanoparticle in brachytherapy was increased therapeutic ratio.
Keywords
Prostate cancer; Brachytherapy; Nanoparticle; Density; Monte Carlo;
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Times Cited By KSCI : 5  (Citation Analysis)
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