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http://dx.doi.org/10.7742/jksr.2014.8.3.137

The Protective Effect of Red Ginseng(RG) Extracts on the Liver of Mice by X-ray Irradiation and Medication of Paraquat Orally  

Ko, InHo (Dept. of Radiological Technology, Cheju Halla University)
Yeo, JinDong (Dept. of Radiological Technology, Sarabol University)
Publication Information
Journal of the Korean Society of Radiology / v.8, no.3, 2014 , pp. 137-145 More about this Journal
Abstract
The protective effects of Red Ginseng on liver damage induced by linac X-ray and paraquat were investigated. To one group of ICR male mice were given in Red Ginseng(200mg/kg/day for 7days, orally) before 5Gy(1.01Gy/min) dose of linac X-ray irradiation. To another group were given in Red Ginseng (200mg/kg/day for 7days, orally) before paraquat(30mg/kg/day, orally) was Radiation irradiation group were given with saline(0.1ml) and 5Gy. Contrast group were given with saline(0.1ml). The levels of H2O2, catalase and MDA in liver tissue were measured. In Red Ginseng to paraquat(RG+PQ) group and Red Ginseng(RG+Rad) group than irradiation group(Rad), the catalase level were significantly increased, and the catalase levels were appeared at radiation protection. The Red Ginseng was significantly decreased to MDA and H2O2 level to paraquat(RG+PQ) group and Red Ginseng(RG+Rad) group than irradiation group(Rad). Therefore, Red Ginseng was very excellent protector on radiation and paraquat of liver in mice.
Keywords
linac; x-ray; MDA; catalase; Red Ginseng; paraquat;
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