Browse > Article
http://dx.doi.org/10.17946/JRST.2017.40.2.06

The Relationship Between Bone Mineral Density and Adipose Tissue of Postmenopausal Women  

Kim, Sun-Hwa (Department of Radiology, HwaMyeong Iisin christian Hospital)
Kim, Jung-Hoon (Department of Radiological Science, Catholic University of Pusan)
Im, In-Chul (Department of Radiological Science, Dong-Eui University)
Publication Information
Journal of radiological science and technology / v.40, no.2, 2017 , pp. 219-228 More about this Journal
Abstract
Postmenopausal women are at increased risk for osteoporosis and obesity due to changes in hormones. The relationship between osteoporosis and body weight is known, and its relation with body fat mass is discussed. The purpose of this study was to evaluate the bone mineral density(BMD) changes of epicardial adipose tissue(EAT) and abdominal subcutaneous fat. The subjects of this study were 160 postmenopausal women who underwent BMD and echocardiography. The thickness of the epicardial adipose tissue was measured in three sections and the BMD were meassured according to the diagnostic criteria. The results of this study that age increase the risk of osteoporosis increases, and as the weight and BMI decrease, the risk of osteoporosis increases(p<0.05). The relationship between changes in bone mineral density and adipose tissue in postmenopausal women, increased epicardial adipose tissue was negatively correlated with the bone mineral density(p<0.05). conversely, increased abdominal subcutaneous fat thickness was positively correlated with bone mineral density(p<0.05). In other words, the effect of bone mineral density on the location of adipose tissue was different. If Echocardiography is used to periodically examine changes in the thickness of the epicardial adipose tissue, it may be prevented before proceeding to osteoporosis.
Keywords
Osteoporosis; Epicardial adipose tissue; Abdominal subcutaneous fat; Postmenopausal women;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 S. Gonnelli, C, Caffarelli, C, Caffarelli, K. Del Santo, A. Cadirni, C. Guerriero, B. Lucani, B. Franci, R. Nuti: The relationship of ghrelin and adiponectin with bone minerial density and bone turnover markers in elderly men, Calcified Tissue Internation, 83(1), 55-60, 2008   DOI
2 Yoo Hye Jin, Park Man Sik, Yang Sae Jeong, Kim Tae Nyan, Lim Kang Il, Kang Hyun Joo, Song Wook, Baik Sei Hyun, Choi Dong Seop, Choi Kyung Mook: The differential relationship between fat mass and bone mineral density by gender and menopausal status, Journal of Bone and Metabolism, 30(1), 47-53, 2012   DOI
3 Dytfeld Joanna, Ignaszak-Szczepaniak, Gowin Ewelina, Michalak Michal, Wanda Horst-Sikorska: Influence of lean and fat mass on bone mineral density(BMD) in postmenopausal women with osteoporosis, Archives of Gerontology and Geriatrics, 53(2), 237-242, 2011   DOI
4 C J Kim, K W Oh, E J Rhee, K H Kim, S K Jo, C H Jung, J C Won, C Y Park, W Y Lee, S W Park, S W Kim: Relationship between body composition and bone mineral density (BMD) in perimenopausal Korean Women, Clinical Endocrinology, 71(1), 18-26, 2009   DOI
5 Youri E C Taes, Bruno Lapauw, Griet Vanbillemont, Veerle Bogaert, Dirk De Bacquer, Hans Zmierczak, Stefan Goemaere, Jean-Marc Kaufman: Fat mass is negatively associated with cortical bone size in young healthy male siblings, Journal of Clinical Endocrinology and Metabolism, 94(7), 2325-2356, 2009   DOI
6 Lan-Juan Zhao, Young-jin Liu, Peng-Yung Liu, James Hamilton, Robert R Recker, Hong-Wen Deng: Relationship of obesity with osteoporosis, Journal of Clinical of Endocrinology and Metabolism, 92(5), 1640-1646, 2007   DOI
7 Agnieszka Janicka, Tishya A L Wren, Monique M Sanchez, Frederick Dorey, Paul S Kim, Steven D Mittelman, Vicente Gilsanz: Fat mass is not beneficial to bone in adolescents and young adults, Journal of Clinical Endocrinology and Metabolism, 92(1), 143-150, 2007   DOI
8 NIH Consensus Development Panel on Osteoporosis Prevention, Diagonosis, and Therapy: Osteoporosis prevention, Diagnosis, and Therapy, Southern Medical Journal, 94(6), 569-642, 2001   DOI
9 Clifford J. Rosen, Anne Klibanski: Bone, Fat, and Body composition: Evoloving concepts in the pathogenesis of osteoporosis, The American Journal of Medicine, 122(5), 409-414, 2009   DOI
10 Toru Akune, Shinsuke Ohba, Satoru Kamekura, Massayuki Yamaguchi, Ung-II Chung, Naoto Kubota, Yasuo Terauchi, Yoshifumi Harada, Yoshiaki Azuma, Kozo Nakamura, Takashi Kadowaki, Hiroshi Kawaguchi: PPARgamma insufficiency enhanes osteoporosis through osteoblast formation from bone marror progenitors, Journal of Clinical Investigation, 113(6), 846-901, 2004   DOI
11 B L Wajchenberg, D Giannella-Neto, M E da Silva, R F Santos: Depot-specific hormonal characteristics of subcutaneous and visceral adipose tissue and their relation to the metaboic syndrome, Hormone and Metabolic Research, 34(11), 616-621, 2002   DOI
12 Khosla S, Atkinson EJ, Riggs BL, Melton 3rd LJ: Relationship between body composition and bone mass in women, Journal of Bone and Mineral Research, 11(6), 857-863, 1996   DOI
13 RJ Maclnnis, C Cassar, CA Nowson, LM Paton, L Flicker, JL Hopper, RG Larkins, JD Wark: Determinants of Bone Density in 30-to 65-Year-Old Women: A Co-Twin Study, Journal of Bone and Mineral Research, 18(9), 1650-1656, 2003   DOI
14 S. M. F. Pluijm, M. Visser, J. H. Smit, C. Popp-Snijders, J. C. Roos, P. Lips: Determinants of Bone Mineral Density in Older Men and Women: Body Composition as Mediator, Journal of Bone and Mineral Research, 16(11), 2142-2151, 2001   DOI
15 K O Klein, K A Larmore, E de Lancey, J M Brown, R V Considine, S G Hassink: Effect of obesity on estradiol level, and its relationship to leptin, bone maturation, and bone mineral density in children, Journal of Clinical Endocrinology & Metabolism, 83(10), 3469-3544, 1998   DOI
16 Clifford J Rosen Mary L Bouxsein: Mechanisms of disease is osteoporosis the obesity of bone?, Nature Clinical practice rheumatology, 2(1), 35-43, 2006   DOI
17 M Yamauchi, T Sugimoto, T Yamaguchi, D Nakaoka, M Kanzawa, S Yano, R Ozuru, T Sugishita, K Chihara: Plasma leptin concentrations are associated with bone mineral density and the presence of vertebral fractures in postmenopausal women, Clinical Endocrinology, 55(3), 341-348, 2001   DOI
18 Lee Jee Eun, Lee Sa Ra, Song Hye Kyung: Muscle mass is a strong correlation factor of total hip BMD among Korean premenopausal women, Osteoporosis and Sarcopenia, 2(2), 99-102, 2016   DOI
19 Skouby Sven O, Gram Jorgen, Andersen Lars F, Sidelmann Johannes, Petersen Kresten R, Jespersen Jorgen: Hormone replacement therapy: Estrogen and progestin effects on plasma C-reactive protein concentrations, American Journal of Obstetrics and Gynecology, 186(5), 969-977, 2002   DOI
20 Agnieszka Janicka, Tishya A L Wren, Monique M Sanchez, Frederick Dorey, Paul S Kim, Steven D Mittelman, Vicente Gilsanz: Fat mass is not beneficial to bone in adolescents and young adults, Journal of Clinical Endocrinology and Metabolism, 92(1), 143-150, 2007   DOI
21 Galic Sandra, Oakhill Jon S, Steinberg Gregory R: Adipose tissue as an endocrine organ, Molecular and Celluar Endocrinology, 316(2), 129-139, 2009
22 Viviane Z Rocha, Peter Libby: Obesity, inflammation, and atherosclerosis, Nature Reviews. Cardiology, 6(6), 399-409, 2009   DOI
23 Patricia Iozzo: Myocardial, pericascular, and Epicardial Fat, American Diabetes Association, 34(2), 371-379, 2011
24 Smith R.: Collagen and disorders for bone(editorial review), Clinical Science, 59, 215-222, 1980   DOI
25 Gianluca Iacobellis, Maria Cristian Ribaudo, Filippo Assael, Elio Vecci, Claudio Tiberti, Alessandra Zappaterreno, Umberto Di Mario, Frida Leonetti: Echocardiographic Epicardial Adipose Tissue is Related to Antoropometric and Clinical parameters of Metabolic Syndrome: A new Indicator of Cardiovascular Risk, The Journal Of Clinical Endocrinology & Metabolism, 88(11), 5163-5168, 2003   DOI
26 Joanna Dytfeld, Magdalena Ignaszak-Szczepaniak, Ewelina Gowin, Michal Michalak, Wanda Horst- Sikorska: Influence of lean and fat mass on bone mineral density(BMD) in postmenopausal women with osteoporosis, Archives of Gerontology and Geriatrics, 53(2), 237-242, 2011   DOI
27 Roberto M. Lang, Michelle Bierig, Richard B. Devereux, Frank A. Flachskampf, Elyse Foster, Patricia A. Pellikka, Michael H. Picard, Mary J. Roman, James Seward, Jack Shanewise Scott Solomon, Kirk T. Spencer, Martin St. John Sutton, William Stewart: Recommendations for chamber quantification: A report from the American society of Echocardiography's Guidelines and Standards Committe and the chamber Quantification Writing Goup, developed in conjunction with the European Association of Echocardiography, Abranch of the European Society of Cardiology, Jounral of American society Echocardiogram, 18, 1440-1463, 2005   DOI
28 Hmed H. Kissebah, Nadarajen Vydelingum, Robert Murray, David J. Evans, Ronald K. Kalkhoff, Peter W. Adams: Relation of body fat distribution to Metabolic Complications of obesity, The Journal of Clinical Endocrinology & Metabolism, 54(2), 254-260, 1982   DOI
29 S. H. Kim, J. H. Kim, C. S. Kim: Risk analysis of factors for metabolic diseases according to the epicardial adipose tissue thickness-which focused on the presented subjects with asymtomatic screening purposes, The Korea Contents association, 16(7), 476-483, 2016
30 Weinstein Louis, Ullery Brian: Identification of at-risk women for osteoporosis screnning, American Journal of Obstetrics and Gynecology, 183(3), 547-549, 2000   DOI
31 Silva Henrique C, Pinheiro Marcelo M, Genaro Patricia S, Castro Charlles H.M, Monteiro Carlos M.C, Fonseca Francisco A.H, Szejnfeld Vera L: Higher prevalence of morphometric vertebral fractures in patients with recent coronary events independently of BMD measurements, Bone, 52(2), 562-567, 2013   DOI
32 D C Bauer, W S Browner, J A Cauley, E S Orwoll, J C Scott, D M Black, J L Tao, S R Cummings: Factors associated with appendicular bone mass in older women. The study of Osteoporotic Fractures Research Group, Annals of Internal Medicine, 118(9), 657-665, 1993   DOI
33 Marcelo M Pinheiro, Charles M Castro, Vera L Szejnfeld: Low femoral bone mineral density and quantitative ultrasound are risk factors for new osteoporotic fracture and total and cardiovascular mortality: a 5-year population-based study of Brazilian elderly women, Journals of Gerontology Series A:Biological Sciences and Medical Sciences, 61(2), 196-203, 2006   DOI
34 Debby den Uyl, Mike T Nurmohamed, Lilian Hy van Tuyl, Hennie G Raterman, Willem F Lems: (Sub) clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis, Arthritis Research Therapy, 13(1), 1-19, 2011   DOI
35 Sundeep Khosla, Elizabeth J, Atkinson, B. Lawrence Riggs, L. Joseph Melton: Relationship between body composition and bone mass in women, Journal of Bone and Mineral Research, 11(6), 857-863, 1996   DOI
36 Wang M.C, Bachrach L.K, Van Loan M, Hudes M, Flegal K.M, Crawford P.B: The relative contributions of lean tissue mass and fat mass to bone density in young women, Bone, 37(4)4, 474-481, 2005   DOI