The Clinical Significance of Cathepsin D and p53 Expression in Locally Advanced Rectal Cancer |
Kim, Jun-Sang
(Departments of Radiation Oncology, College of Medicine, Chungnam National University)
Lee, Sheng-Jin (Departments of Pathology, College of Medicine, Chungnam National University) Kim, Jin-Man (Departments of Pathology, College of Medicine, Chungnam National University) Cho, Moon-June (Departments of Radiation Oncology, College of Medicine, Chungnam National University) |
1 | Janjan NA, Khoo VS, Abbruzzese J, et al. Tumor downstaging andsphincter preservation with preoperative chemoradiation in locally advanced rectal cancer: The M.D. Anderson Cancer Center experience. Int J Radiat Oncol Biol Phys 1999;44:1027-1038 DOI ScienceOn |
2 | Minsky BD, Cohen AM, Enker WE, et al. Preoperative 5-FU, low-dose leucovorin, and radiation therapy for locally advanced and unresectable rectal cancer. Int J Radiat Oncol Biol Phys 1997;37:289-295 DOI ScienceOn |
3 | Kim JS, Kim JS, Cho MJ, Song KS, Yoon WH. Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 2002;54:403-408 DOI ScienceOn |
4 | van der Stappen JW, Williams AC, Maciewicz RA, Paraskeva C. Activation of cathepsin B, secreted by a colorectal cancer cell line requires low pH and is mediated by cathepsin D. Int J Cancer 1996;67:547-554 DOI ScienceOn |
5 | Talieri M, Papadopoulou S, Scorilas A, et al. Cathepsin B and cathepsin D expression in the progression of colorectal adenoma to carcinoma. Cancer Letters 2004;205:97-106 DOI ScienceOn |
6 | Lane DP. p53, guardian of the genome. Nature 1992;358:15-16 DOI ScienceOn |
7 | Berchem G, Glondu M, Gleizes M, et al. Cathepsin-D affects multiple tumor progression steps in vivo: proliferation, angiogenesis and apoptosis. Oncogene 2002;21:5951-5955 DOI ScienceOn |
8 | Munro AJ, Lain S, Lane DP. P53 abnormalities and outcomes in colorectal cancer: a systematic review. Br J Cancer 2005;92:434-444 DOI PUBMED |
9 | Riley LB, Lange MK, Browne J, et al. Analysis of cathepsin D in human breast cancer: Usefulness of the processed 31 ku active form of the enzyme as a prognostic indicator in node-negative and node-positive patients. Breast Cancer Res Treat 2000;60:173-179 DOI ScienceOn |
10 | Morgan M, Koorey D, Painter D, et al. p53 and DCC immunohistochemistry in curative rectal cancer surgery. Int J Colorectal Dis 2003;18:188-195 PUBMED |
11 | Wu GS, Saftig P, Peters C, El-Deiry WS. Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity. Oncogene 1998;16:2177-2183 DOI |
12 | Chabowski A, Sulkowska M, Sulkowski S, Famulski W, Skrzydlewska E, Kisielewski W. Immunohistochemical evaluation of cathepsin D expression in colorectal cancer. Folia Histochem Cytobiol 2001;39:153-154 |
13 | Theodoropoulos GE, Panoussopoulos D, Lazaris AC, Golematis BC. Evaluation of cathepsin D immunostaining in colorectal adenocarcinoma. J Surg Oncol 1997;65:242-248 DOI ScienceOn |
14 | Rochefort H, Garcia M, Glondu M, et al. Cathepsin D in breast cancer: mechanisms and clinical applications, a 1999 overview. Clin Chim Acta 2000;291:157-170 DOI ScienceOn |
15 | Ferrandina G, Scambia G, Bardelli F, Benedetti Panici P, Mancuso S, Messori A. Relationship between cathepsin D content and disease-free survival in node-negative breast cancer patients: a meta-analysis. Br J Cancer 1997;76:661-666 DOI PUBMED ScienceOn |
16 | Rochefort H. Cathepsin D in breast cancer. Breast Cancer Res Treat 1990;16:3-13 DOI |
17 | Gallego MG, Acenero MJ, Ortege S, Delgdo AA, Cantero JL. Prognostic influence of p53 nuclear overexpression in colorectal carcinoma. Dis Colon Rectum 2000;43:971-975 DOI ScienceOn |
18 | Sebzda T, Saleh Y, Gburek J, et al. Cathepsin D expression in human colorectal cancer: relationship with tumour type and tissue differentiation grade. J Exp Ther Oncol 2005;5:145-150 PUBMED |
19 | Sis B, Sagol O, Kupelioglu A, et al. Prognostic significance of matrix metalloproteinase-2, cathepsin D, and tenascin-C expression in colorectal carcinoma. Pathol Res Pract 2004;200:379-387 DOI ScienceOn |
20 | Wiggenraad R, Tamminga R, Blok P, Rouse R, Hermans J. The prognostic significance of p53 expression for survival and local control in rectal carcinoma treated with surgery and postoperative radiotherapy. Int J Radiat Oncol Biol Phys 1998;41:29-35 DOI ScienceOn |
21 | Ioachim EE, Goussia AC, Machera M, Tsianos EV, Kappas AM, Agnantis NJ. Immunohistochemical evaluation of cathepsin D expression in colorectal tumours: a correlation with extracellular matrix components, p53, pRb, bcl-2, c-erbB-2, EGFR and proliferation indices. Anticancer Res 1999;19:2147-2155 PUBMED |
22 | Choi C, Kim M, Yoo S, et al. The clinicopathological factors that determine a local recurrence of rectal cancers that have been treated with surgery and chemoradiotherapy. J Korean Soc Ther Radiol Oncol 2006;24:255-262 과학기술학회마을 |
23 | Ikeguchi M, Fukuda K, Oka S, et al. Clinicopathological significance of cathepsin D expression in gastric adenocarcinoma. Oncology 2001;61:71-78 DOI ScienceOn |
24 | Oh-e H, Tanaka S, Kitadai Y, Shimamoto F, Yoshihara M, Haruma K. Cathepsin D expression as a possible predictor of lymph node metastasis in submucosal colorectal cancer. Eur J Cancer 2001;37:180-188 DOI ScienceOn |
25 | Kanber Y, Demirbag NR, Sam AD, Aydin N. Cathepsin D expression in colorectal adenocarcinomas and adenomas. Int J Biol Markers 2002;17:165-168 DOI PUBMED |
26 | Rochefort H, Liaudet-Coopman E. Cathepsin D in cancer metatasis: a protease and a ligand. APMIS 1999;107:86-95 DOI ScienceOn |
27 | Chabowski A, Skrzydlewska E, Sulkowska M, et al. Cathepsin D activity in colorectal cancer. Ann Acad Med Bialostoc 2001;46:38-46 |
28 | Ioachim E, Kitsiou E, Charalabopoulos K, et al. Immunohistochemical evaluation of cathepsin D in normal, hyperplastic and malignant endometrium: correlation with hormone receptor status c-erbB-2, p53, Rb proteins and proliferation associated indices. Int J Gynecol Cancer 2003;13:344-351 DOI ScienceOn |
29 | Tannapfel A, Nusslein S, Fietkau R, Katalinic A, Kockerling F, Wittekind C. Apoptosis, proliferation, bax, bcl-2 and p53 status prior to and after preoperative radiochemotherapy for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 1998;41:585-591 DOI ScienceOn |
30 | Li S, Kim JS, Kim JM, et al. Epidermal growth factor receptor as a prognostic factor in locally advanced rectal-cancer patients treated with preoperative chemoradiation. Int J Radiat Oncol Biol Phys 2006;65:705-712 DOI ScienceOn |
31 | Talieri M, Papadopoulou S, Scorilas A, et al. Cathepsin B and cathepsin D expression in the progression of colorectal adenoma to carcinoma. Cancer Lett 2004;205:97-106 DOI ScienceOn |
32 | Korean National Statistical Office. Annual report on the cause of death statistic in 2005. 2006 |
33 | Sauer R, Becker H, Hohenberger W, et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004;351:1731-1740 DOI ScienceOn |
34 | Ioachim E, Charchanti A, Stavropoulos N, Athanassiou E, Bafa M, Agnantis NJ. Expression of cathepsin D in urothelial carcinoma of the urinary bladder: an immunohistochemical study including correlations with extracellular matrix components, CD44, p53, Rb, c-erbB-2 and the proliferation indices. Anticancer Res 2002;22:3383-3388 PUBMED |
35 | Duffy MJ. Role of proteolytic enzymes in cancer invasion and metastasis. Clin Exp Metastasis 1992;10:145-155 DOI |