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Malignant Melanoma of the Vagina: A Report of 2 Cases  

Kim, Ok-Bae (Department of Radiation Oncology, Dongsan Medical Center, School of Medicine, Keimyung University)
Kim, Jin-Hee (Department of Radiation Oncology, Dongsan Medical Center, School of Medicine, Keimyung University)
Jung, Young-Yeon (Department of Radiation Oncology, Dongsan Medical Center, School of Medicine, Keimyung University)
Cho, Chi-Heum (Department of Gynecology, Dongsan Medical Center, School of Medicine, Keimyung University)
Choi, Tae-Jin (Department of Bio-physics Medical Engineering, Dongsan Medical Center, School of Medicine, Keimyung University)
Publication Information
Radiation Oncology Journal / v.23, no.2, 2005 , pp. 111-115 More about this Journal
Abstract
Primary malignant melanoma of the vagina is an extremely rare genital neoplasm occurring mainly on postmenopausal women. It has a worse prognosis than cutaneous melanomas, because of the high rate of loco-regional recurrences and rapid systemic dissemination. In the past, radical surgical extirpation as the primary management had been recommended to improve loco-regional control, and possibly overall survival. However, the prognosis was poor In spite of such a radical approache. Recently, more conservative treatment such as wide local excision combined with adjuvant high-dose fraction radiotherapy seems to have premising results. Primary radiation therapy could be served as an alternative to surgery for patients with lesion less than 3 cm in diameter. We report 2 cases of primary vaginal malignant melanoma treated with radiotherapy.
Keywords
Malignant melanoma; Vagina; Radiation therapy;
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