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Three-Dimensional Dosimetry Using Magnetic Resonance Imaging of Polymer Gel  

Oh Young-Taek (Department of Radiation Oncology, Ajou University School of Medicine)
Kang Haejin (Department of Radiology, Ajou University School of Medicine)
Kim Miwha (Department of Radiation Oncology, Ajou University School of Medicine)
Chun Mison (Department of Radiation Oncology, Ajou University School of Medicine)
Kang Seung-Hee (Department of Radiation Oncology, Ajou University School of Medicine)
Suh Chang Ok (Department of Radiation Oncology, Yonsei University College of Medicine)
Chu Seong Sil (Department of Radiation Oncology, Yonsei University College of Medicine)
Seong Jinsil (Department of Radiation Oncology, Yonsei University College of Medicine)
Kim Gwi Eon (Department of Radiation Oncology, Yonsei University College of Medicine)
Publication Information
Radiation Oncology Journal / v.20, no.3, 2002 , pp. 264-273 More about this Journal
Abstract
Purpose : Three-dimensional radiation dosimetry using magnetic resonance imaging of polymer gel was recently introduced. This dosimetry system is based on radiation induced chain polymerization of acrylic monomers in a muscle equivalent gel and provide accurate 3 dimensional dose distribution. We planned this study to evaluate the clinical value of this 3-dimensional dosimetry. Materials and Methods: The polymer gel poured into a cylindrical glass flask and a spherical glass flask. The cylindrical test tubes were for dose response evaluation and the spherical flasks, which is comparable to the human head, were for isodose curves. T2 maps from MR images were calculated using software, IDL. Dose distributions have been displayed for dosimetry. The same spherical flask of gel and the same irradiation technique was used for film and TLD dosimetry and compared with each other. Results : The R2 of the gel respond linearly with radiation doses in the range of 2 to 15 Gy. The repeated dosimetry of spherical gel showed the same isodose curves. These isodose curves were identical to dose distributions from treatment planning system especially high dose range. In addition, the gel dosimetry system showed comparable or superior results with the film and TLD dosimetry. Conclusion : The 3-dimensional dosimetry for conformal radiation therapy using MRI of polymer gal showed stable and accurate results. Although more studies are needed for convenient clinical application, it appears to be a useful tool for conformal radiation therapy.
Keywords
Conformal radiotherapy; MRI; Dosimetry; Radiation dose; Polymer gel;
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