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http://dx.doi.org/10.4132/jptm.2018.07.15

Squamous Metaplasia in Pleomorphic Adenoma: A Diagnostic and Prognostic Enigma  

Sharma, Swati (Department of Oral and Maxillofacial Pathology and Microbiology, I.T.S. Dental College, Hospital and Research Centre)
Mehendiratta, Monica (Department of Oral and Maxillofacial Pathology and Microbiology, I.T.S. Dental College, Hospital and Research Centre)
Chaudhary, Nivedita (Department of Oral and Maxillofacial Pathology and Microbiology, I.T.S. Dental College, Hospital and Research Centre)
Gupta, Vineet (Department of Oral and Maxillofacial Pathology and Microbiology, I.T.S. Dental College, Hospital and Research Centre)
Kohli, Maulshree (Department of Oral and Maxillofacial Pathology and Microbiology, I.T.S. Dental College, Hospital and Research Centre)
Arora, Anjana (Department of Oral Medicine and Radiology, I.T.S. Dental College, Hospital and Research Centre)
Publication Information
Journal of Pathology and Translational Medicine / v.52, no.6, 2018 , pp. 411-415 More about this Journal
Abstract
Pleomorphic adenoma (PA) is the most common benign salivary gland tumor. Histologically, squamous metaplasia has been reported in PA, but has rarely been documented as being extensive enough to cause significant misdiagnosis. Here, we present an unusual case of PA in a 50-year-old female patient presenting with swelling on the postero-lateral aspect of the palate for a week. Histopathologically, the tumor exhibited the features of conventional PA with extensive squamous metaplasia and giant keratotic lamellae in cyst-like areas. Such exuberant squamous metaplasia and keratin can be a diagnostic and prognostic pitfall and lead to overtreatment of the patient.
Keywords
Squamous metaplasia; Pleomorphic adenoma; Pathology;
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