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http://dx.doi.org/10.4132/KoreanJPathol.2013.47.2.100

Guideline Recommendations for EGFR Mutation Testing in Lung Cancer: Proposal of the Korean Cardiopulmonary Pathology Study Group  

Shim, Hyo Sup (Department of Pathology, Yonsei University College of Medicine)
Chung, Jin-Haeng (Department of Pathology, Seoul National University Bundang Hospital)
Kim, Lucia (Department of Pathology, Inha University School of Medicine)
Chang, Sunhee (Department of Pathology, Ilsan Paik Hospital, Inje University College of Medicine)
Kim, Wan-Seop (Department of Pathology, Konkuk University School of Medicine)
Lee, Geon Kook (Department of Pathology, National Cancer Center)
Jung, Soon-Hee (Department of Pathology, Yonsei University Wonju College of Medicine)
Jang, Se Jin (Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine)
Publication Information
Journal of Pathology and Translational Medicine / v.47, no.2, 2013 , pp. 100-106 More about this Journal
Abstract
Mutations of the epidermal growth factor receptor (EGFR) are the strongest predictive factor for response to EGFR tyrosine kinase inhibitors (TKIs), such as gefitinib and erlotinib. EGFR TKIs are approved in Korea as a first-line treatment for lung cancer patients with mutated EGFR. Rapid and accurate EGFR mutation testing is essential for patient selection and establishing targeted therapies with EGFR TKIs. Thus, a standard set of guideline recommendations for EGFR mutation testing suitable for the Korean medical community is necessary. In this article, we propose a set of guideline recommendations for EGFR mutation testing that was discussed and approved by the Cardiopulmonary Pathology Study Group of the Korean Society of Pathologists.
Keywords
Mutation; Receptor, epidermal growth factor; Guideline;
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