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Endoscopic Bio-Imaging Using Optical Coherence Tomography  

Ahn, Yeh-Chan (Department of Biomedical Engineering, Pukyong National University)
Brenner, Matthew (Beckman Laser Institute, University of California at Irvine)
Chen, Zhongping (Beckman Laser Institute, University of California at Irvine)
Publication Information
Journal of the Korean Society for Nondestructive Testing / v.31, no.5, 2011 , pp. 466-471 More about this Journal
Abstract
Optical coherence tomography(OCT) is an emerging medical diagnostic tool that draws great attention in medical and biological fields. It has a 10-100 times higher spatial resolution than that of the clinical ultrasound but lower imaging depth such as 1-2 mm. In order to image internal organs, OCT needs an endoscopic probe. In this paper, the principle of Fourier-domain optical coherence tomography with high-speed imaging capability was introduced. An OCT endoscope based on MEMS technology was developed. It was attached to the Fourier-domain OCT system to acquire three-dimensional tomographic images of gastrointestinal tract of New Zealand white rabbit. The endoscope had a two-axis scanning mirror that was driven by electrostatic force. The mirror stirred an incident light to sweep two-dimensional plane by scanning. The outer diameter of the endoscope was 6 mm and the mirror diameter was 1.2 mm. A three-dimensional image rendered by 200 two-dimensional tomographs with $200{\times}500$ pixels was displayed within 3.5 seconds. The spatial resolution of the OCT system was 8 ${\mu}m$ in air.
Keywords
Optical Coherence Tomography; Endoscope; Two-Axis Scanning Mirror; Microelectromechanical System (MEMS) Technology; Gastrointestinal Imaging;
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