Browse > Article
http://dx.doi.org/10.15204/jkobgy.2019.32.3.245

Review on Clinical Studies of Traditional Korean Medicine Treatment for Atrophic Vaginitis  

Nam, Eun-Young (Dept. of Obstetrics and Gynecology, College of Korean Medicine, Ga-Chon University)
Publication Information
The Journal of Korean Obstetrics and Gynecology / v.32, no.3, 2019 , pp. 245-262 More about this Journal
Abstract
Objectives: The purpose of this study is to review clinical studies of traditional Korean medicine treatment (herb medicine) on vaginal atrophy. Methods: Key words "Vaginal atrophy", "Vulvovaginal atrophy", "Vaginal dryness", "Atrophic vaginitis", "Herb medicine", "Acupuncture", "Moxibustion", "Catgut embedding" were searched on 11 database systems (PMC, CENTRAL, EMBASE, CNKI, KTKP, KISS, NDSL, OASIS, DBpia, KMBASE, RISS) on May 31th 2019. In all searches, limits were set for MeSH (human) and language (English, Chinese or Korean). Results: 18 controlled clinical trials were collected in accordance with the selection and exclusion criteria. The types of intervention were herbal medicine, and types of herbal medicine were decoction, cream, suppository, oil, ect. The study results and methods of intervention were analyzed. Conclusions: Among the 18 trials, 5 studies showed that herbal medicine with hormone or antiprotozoal therapy was more effective than hormone or antiprotozoal therapy alone. And 2 studies showed that herbal medicine treatment was more effective than oil treatment of topical use. There was no abnormal vaginal bleeding, breast swelling and pain in TCM group.
Keywords
Atrophic Vaginitis; Vaginal Dryness; Menopause; Herbal Medicine; Traditional Korean Medicine;
Citations & Related Records
Times Cited By KSCI : 6  (Citation Analysis)
연도 인용수 순위
1 Tami P. Atrophic vaginitis. The Journal for nurse practitioners. 2011;7(6):502-12.   DOI
2 MacBride MB, Rhodes DJ, Shuster LT. Vulvovaginal atrophy. Mayo Clin Proc. 2010;85(1):87-94.   DOI
3 Park HM. Climacteric symptoms & hormone therapy. Journal of the Korean medical association. 2006;49(1):11-29.   DOI
4 Lee A, et al. Therapeutic approaches to atrophic vaginitis in postmenopausal women: A systematic review with a network meta-analysis of randomized controlled trials. Journal of menopausal medicine. 2018;24(1):1-10.   DOI
5 Pinkerton, JAV, et al. The 2017 hormone therapy position statement of the north American menopause society. Menopause. 2017;24(7):728-53.   DOI
6 Lethaby A, Ayeleke RO, Roberts H. Local oestrogen for vaginal atrophy in postmenopausal women. Cochrane database of systematic reviews. 2016, 8:1-111.
7 Lee DK, et al. The short-term effect of black cohosh on vaginal atrophy and safety in postmenopausal women. J Korean Obstet Gynecol. 2007;50(2):306-13.
8 Kim SN, et al. Phytoestrogenic effects of combined plant extracts on the change of bone metabolism of OVX Rats. Korean journal of food science and technology. 2008;40(3):316-20.
9 Kim MY, et al. A study on heart rate variability(HRV) of women with atrophic vaginitis. J Korean Obstet Gynecol. 2015;28(3):11-20.   DOI
10 Heo SJ, et al. A study on urinary incontinence, interstitial cystitis, atrophic vaginitis of elderly women using senior welfare center and nursing home and the cognition of traditional korean medicine. J Korean Obstet Gynecol. 2010;23(3):123-38.   DOI
11 Lee JE, et al. A report on the clinical efficacy of Daejo-hwan(DJH) about the dryness of vagina and sexual satisfaction in climacteric women. 2005;18(3):203-14.
12 Cho YD, Lim SM, Kim HJ. Clinical report on three cases of vaginal dryness treated with gagam-chungsimyeonjaeum. Journal of physiology & pathology in Korean medicine. 2004;18(4):1225-7.
13 Kang NH, et al. The clinical study on 2 cases of atrophic vaginitis in menopausal women. J Korean Obstet Gynecol. 2016;29(4):34-45.   DOI
14 Baek SE, et al. Systematic review of fumigation therapy for atrophic vaginitis. J Korean Obstet Gynecol. 2016;29(1):92-101.   DOI
15 Wei JN, et al. Jia wei bu shen zhi dai tang zhi liao jue jing hou wei suo xing yin dao yan de liao xiao guan cha. Guiding journal of traditional Chinese medicine and pharmacy. 2018;24(5):99-100, 107.
16 Wang YC. Clinical observation on modified bushen zhidai decoction in treating postmenopausal atrophic vaginitis. Journal of traditional Chinese medicine. 2019;34(4):562-4.
17 Yao PL. Yin ke ning xilie yao zhiliao laonian xing yindao yan 38 li. Zhongguo zhong yiyao xinxi zazhi. 2000;7(10):55.
18 Ren L. Yi yin tang he yi yin you zhi liao wei suo xing yin dao yan 52 li lin chuang liao xiao guan cha. Chinese journal of ethnomedicine and ethnopharmacy. 2014;5:60-1.
19 Wang YL. With the ziyinrunqiao particles in the treatment of vaginal dryness (liver and kidney yin deficiency type) middle-aged and old women of clinical curative effect evaluation research. Master's thesis of Chinese studies, Chengdu university of traditional Chinese medicine. Chengdu, China. 2018;05:1-93.
20 Reed SD, et al. Vaginal, endometrial, and reproductive hormone findings: Randomized, placebo-controlled trial of black cohosh, multibotanical herbs, and dietary soy for vasomotor symptoms: The herbal alternatives for menopause (HALT) study. Menopause: The journal of the north American menopause society. 2008;15(1):51-8.   DOI
21 Li ZP, Wang YQ. Clinical Study on Sanqiang Soup Combined with Hormone in Treating Atrophic Vaginitis with Yin Deficiency and Dampness-heat Syndrome. Chinese Journal of Information on Traditional Chinese Medicine. 2012;19(4):9-11.   DOI
22 Yu YH. Ni er ci chun lian he bao fu kang shuan zhi liao wei suo xing yin dao yan de lin chuang ti hui. Inner Mongol journal of traditional Chinese medicine. 2012;24:98-9.
23 Huang XL. Kun tai jiao nang lian he ci san chun ru gao zhi liao wei suo xing mi niao sheng zhi xi ji bing de lin chuang liao xiao guan cha. Guide of Chinese medicine. 2019;17(5):165-6.
24 Wang ZX, Zheng Y, Chen JM, The efficacy of kuntai capsule combined with tinidazole suppositories local treatment on atrophic vaginitis. Journal of practical Gynecologic Endocrinology (Electronic Edition). 2018;23(5):37-9.
25 Hou LN. San qiang tang lian he ji su zhi liao yin xu shi re xing wei suo xing yin dao yan lin chuang yan jiu. Asia-Pacific Traditional Medicine. 2016;12(18):138-9.
26 Mu HY. Kun tai jiaonang lianhe fufang shaji zi you shuan yong yu zhiliao weisuo xing yindao yan de linchuang pingjia. Modern Medicine and Health Research. 2018;2(2):17.
27 Shi JY, Liang XZ, Chen X. Observation of curative effect of Kuntai capsules combined with compound Shajizi suppository on the treatment of atrophic vaginitis. Hebei Journal of Traditional Chinese Medicine. 2016;38(5):662-5.
28 Sun NX, et al. Black cohosh improves vaginal atrophy in postmenopausal women. 2012;3(33):339-42.   DOI
29 Wang YQ, et al. Clinical effect of xianling gubao capsule combined with baofukang suppository in treating atrophic vaginitis. 2010;30(7):766-8.
30 Chen R, et al. Randomized, double-blind, placebo-controlled study of modified erzhi granules in the treatment of menopause-related vulvovaginal atrophy. Evidence-based complementary and alternative medicine. 2018:1-15.
31 Noh YH, et al. The natural substance MS-10 improves and prevents menopausal symptoms, including colpoxerosis, in clinical research. Journal of medical food. 2016;19(3):228-37.   DOI
32 Lee DK, et al. The short-term effect of black cohosh on vaginal atrophy and safety in postmenopausal women. J Korean Obstet Gynecol. 2007;50(2):306-13.
33 The society of Korean medicine obstetrics and gynecology. Oriental obstetrics & gynecology Ha. 3rd edition. Seoul: Euiseongdang. 2016:228-60, 277-90.