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http://dx.doi.org/10.15204/jkobgy.2017.30.4.059

The Effect of Integrated Medicine for Polycystic Ovary Syndrome Subfertility Patients; A Systematic Review and Meta-Analysis  

Bae, Ju-Eun (Dept. of Korean OB & GY, School of Korean Medicine, Pusan National University)
Park, Kyung-Dug (Dept. of Korean OB & GY, School of Korean Medicine, Pusan National University)
Yoon, Young-Jin (Dept. of Korean OB & GY, School of Korean Medicine, Pusan National University)
Publication Information
The Journal of Korean Obstetrics and Gynecology / v.30, no.4, 2017 , pp. 59-76 More about this Journal
Abstract
Objectives: The purpose of this study is to investigate the effect on both herbal medicine periodic therapy and western medicine for polycystic ovary syndrome subfertility. Methods: We searched 8 electronic databases and search keywords were 'PCOS' and 'periodic therapy' or 'cyclic treatment'. We included randomized controlled clinical trials (RCTs) using the periodic therapy combined western medicine for PCOS patients. Results: We selected 8 studies. In studies, there were three studies in which the menstrual cycle was divided into 2 periods, one study divided into 3 periods, and four study divided into 4 periods. The meta-analysis of the 7 trials indicated that pregnancy rates integrated clomiphene and periodic therapy were higher than clomiphene alone. Conclusions: The periodic therapy combined western medicine for PCOS subfertility patients seems to improve pregnancy rates from this research. However, this result should be taken cautiously by unclear risk of bias. It would be necessary to fulfill further clinical study with herbal medicine periodic therapy on PCOS in Korean medicine to establish standard evidence of them.
Keywords
Poly Cystic Ovary Syndrome (PCOS); Periodic Therapy; Integrated Medicine; Clomiphene; Subfertility;
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Times Cited By KSCI : 16  (Citation Analysis)
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