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http://dx.doi.org/10.5806/AST.2011.24.6.407

Chip-based microcapillary HPLC for proteomic analysis  

Kim, Bo-Ra (Lee Gil Ya Cancer and Diabetes Institute, Gachon University)
Park, Jong-Moon (Lee Gil Ya Cancer and Diabetes Institute, Gachon University)
Lee, Hoo-Keun (Lee Gil Ya Cancer and Diabetes Institute, Gachon University)
Publication Information
Analytical Science and Technology / v.24, no.6, 2011 , pp. 407-413 More about this Journal
Abstract
Over the last decade sophisticated and powerful microcapillary HPLC for proteomic analysis have been developed increasingly and interfaced with high resolution tandem mass spectrometers. Separation prior to mass spectrometric (MS) analysis removes impurities, and concentrates analytes in the narrow elution peaks, resulting in increased sensitivity of MS analysis. This review will focus on the recent advances of on-line highperformance separation techniques based on microfluidic chips for complex proteomic analysis.
Keywords
microcapillary; HPLC; microfluidic chip; proteomic analysis;
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1 M.-Y. Brusniak, B. Bodenmiller, D. Campbell, K. Cooke, J. Eddes, A. Garbutt, H. Lau, S. Letarte, L. N. Mueller, V. Sharma, O. Vitek, N. Zhang, R. Aebersold and J. D. Watts, BMC Bioinformatics, 9, 542 (2009).   DOI   ScienceOn
2 M. A. Bynum, H. Yin, K. Felts, Y. M. Lee, C. R. Monell and K. Killeen, Anal. Chem., 81, 8818-8825 (2009).   DOI   ScienceOn
3 J. R. Rasmussen, J. Davis, J. M. Risley and R. L. Van Etten, J. Am. Chem. Soc., 114(3), 1124-1126 (1992).   DOI
4 J. B. Fenn, M. Mann, C. K. Meng, S. F. Wong and C. M. Whitehouse, Science, 246, 64-71 (1989).   DOI
5 M. Karas and F. Hillenkamp, Anal. Chem., 60, 2299- 2301 (1995).
6 M. Wilm and M. Mann, Anal. Chem., 68, 1-8 (1996).
7 A. Shevchenko, M. Wilm, O. Vorm, and M. Mann, Anal. Chem., 68, 850-858 (1996).   DOI   ScienceOn
8 Y. Ishihama, J. of Chromatogr. A, 1067, 73-80 (2005).   DOI   ScienceOn
9 M. A. Moseley, L. J. Deterding, K. B. Tomer and J. W. Jorgenson, Anal. Chem., 63, 1467-1473 (1991).   DOI   ScienceOn
10 L. A. Holland and J. W. Jorgenson, Anal. Chem., 67, 3275-3283 (1995).   DOI   ScienceOn
11 Y. Shen, R. J. Moore, R. Zhao, J. Blonder, D. L. Auberry, C. Masselon, L. Pasa-Tolic, K. K. Hixson, K. J. Auberry and R. D. Smith, Anal. Chem., 75, 3596-3605 (2003).   DOI   ScienceOn
12 H. Yin and K. Killeen, J. Sep. Sci. 30, 1427-1434 (2007).   DOI   ScienceOn
13 M. E. Belov, G. A. Anderson, M. A. Wingerd, H. R. Udseth, K. Tang, D. C. Prior, K. R. Swanson, M. A. Buschbach, E. F. Strittmatter and R. J. Moore, J. Am. Soc. Mass Spectrom., 15, 212-232 (2004).   DOI   ScienceOn
14 H. Yin, K. Killeen, R. Brennen, D. Sobek, M. Werlich and T. Goor, Anal. Chem., 77, 527-533 (2005).   DOI   ScienceOn
15 M. H. Fortier, E. Bonneil, P. Goodley and P. Thibault, Anal. Chem., 77, 1631-1640 (2005).   DOI   ScienceOn
16 H. Lee, E. C. Yi, B. Wen, T. P. Reily, L. Pohl, S. Nelson, R. Aebersold and D. R. Goodlett, J. Chromatogr. B, 803, 101-110 (2004).   DOI   ScienceOn