Browse > Article
http://dx.doi.org/10.5806/AST.2009.22.6.504

Distribution of hazardous heavy metals in commercial herbal medicines classified by plant parts used in seoul  

Kim, Donggyu (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Kim, Bogsoon (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Han, Eunjung (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Han, Changho (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Kim, Oukhee (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Choi, Byunghyun (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Hwang, Insook (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Chae, Youngzoo (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Kim, Minyoung (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Park, Seungkook (Institute of Life Science and Resources, Kyung Hee University)
Publication Information
Analytical Science and Technology / v.22, no.6, 2009 , pp. 504-513 More about this Journal
Abstract
In this study, the safety of commercial herbal medicines was evaluated by determining concentration of hazardous heavy metals. 3,152 samples (244 types) purchased by individual packing unit from market in Seoul, were analyzed using ICP-MS and mercury analyzer. As a result, the content (mg $kg^{-1}$) of Pb was higher in the above-ground part (0.92) than underground part (0.43). But in case of As and Cd contents, there is slightly higher in the underground-parts (0.26, 0.13) than the above-ground parts (0.18, 0.08). There were many herbal medicines exceeding regulatory limits of Cd comparing with other metals. The levels of Hg seemed to be different between above-ground part(0.009) and underground part (0.008) but there was no sample exceeding tolerance limits. In the comparison of imported samples with domestic herbal medicines, it was shown that Pb, As, and Hg were measured highly in the imported ones, Cd was not significantly different (t-test, p<0.05). The significant correlation was observed between Pb and As (r=0.386, p<0.01) but there was no difference in other parts. The heavy metal contamination of herbal medicines measured in total amount of respective heavy metals (mg $kg^{-1}$) was high in Flos (6.241) and Caulis (2.238), and decreased in the order of Cortex (1.634), Herba (1.154), Perithecium (0.861), Rhizoma (0.828), Radix (0.825), Fructus (0.475), and was low in Semen (0.422) (ANOVA-test, p<0.05).
Keywords
heavy metals; herbal medicines; ICP-MS;
Citations & Related Records
Times Cited By KSCI : 5  (Citation Analysis)
연도 인용수 순위
1 G. B. Jung, B.Y. Kim, K. S. Kim, J.S. Lee and I. S. Ryu, Korean J. Soil Sci. Fert., 29, 158(1996)
2 김형국, '약전해설서', 346, 파마코리아나, 한국, 2008
3 J. H. Kim, J. Y. Yang and Y. S. Moon, Korean J. of the Environmental Sciences, 16, 1287(2007)   DOI
4 M. K. Park, Korean J. of the Env. Sci., 16, 241(2007)   과학기술학회마을   DOI
5 Raymond Niesink, Mannfred A. Hollinger, John De Vries, 'Toxicology-Principles and Applicationsv, 17-38, CRC Press, Inc., Florida, USA, 1996
6 Y. Shin, J. E. Kwak, C. H. Han, Y. S. Hwang, A. S. Park, D. G. Kim, E. J. Han, S. J. Jung, B. S. Kim, B. H. Choi, Report of Seoul Institute of Health and Enviroment, Korea, 43, 226(2007)
7 영인과학, 'ICP-MS 입문서', 28-39, 한국, 2005
8 Y. Y. Cha, S. K., Hea, B. C. Cha and S. H. Sea, Korean J. Oriental Physiology & Pathology, 21, 226(2007)   과학기술학회마을   ScienceOn
9 식품의약품안전청, 고시 제2009-35호, 2009
10 I. S. Yu and Y. J. Hong, Report of Seoul Institute of Health and Enviroment, Korea, 42, 62(2006)
11 G. G. S. Holmgren, M. W. Meyer, R. L. Chaney and R. B. Daniels, American J. Environ. Qual., 22, 335(1993)   DOI   ScienceOn
12 S. D. Lee, and K. S. Park, Korean J. Oriental Preventive Medical Society, 5, 31(2001)   과학기술학회마을
13 식품의약품안전청, '한약재표준제조공정지침', 3, 2008
14 한국보건산업진흥원, '한약품질및유통관리제도 조사 연구', 2, 한국, 2000
15 S. D. Lee, H. M. Park, J. C. Lee and Y. B, Kook, Korean J. of Oriental Med., 24, 59(2003)
16 Y. J. Hong, J. E. Kwak, W. H. Park, Y. S. Hwang, E. J. Kim, A. S. Park, Y. Shin, E. J. Han, J. M. Lee, B. S. Kim and B. Y. Choi, Report of Seoul Institute of Health and Enviroment, Korea, 42, 286(2006)
17 한의약육성법, 법률 제6965호(2003.8.6)
18 한국의약품수출입협회, '한약재감별주해', 15-38, 대영, 한국, 2003
19 S. H. Lee, H. Y. Choi and C. H. Park, Korean J. of Biotechnol Bioeng., 18, 90(2003)   과학기술학회마을
20 KOLAS (Korea Laboratory Accreditation Scheme), KT208호
21 J. E. Kwak, Y. Shin, C. H. Han, Y. S. Hwang, A. S. Park, D. G. Kim, E. J. Han, S. J. Jung, B. S. Kim, B. H. Choi and M. Y. Kim, Report of Seoul Institute of Health and Enviroment, Korea, 43, 129(2007)
22 서부일, 이제현, 최호영, 권동렬, 부영민, '한약본초학', 29, 영림사, 한국, 2006
23 박창호, 강신인, '한약재포제기술', 15, 청문각, 한국, 2006
24 J. S. Kim, S. W. Hwang, J. M. Kim and J. Y. MA, Korean J. Yakhak Hoeji, 45, 448(2001)   과학기술학회마을
25 D. H. Jung and M. K. Park, Korean J. of the Environmental Sciences, 17, 129(2008)   과학기술학회마을   DOI
26 김복순, 단국대학교 박사학위논문, 58(2007)