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http://dx.doi.org/10.5806/AST.2008.21.6.480

The monitoring of some heavy metals in oriental mineral medicines  

Han, Eunjung (Center for Environmental Technology, Korea Institute of Science and Technology)
Chung, Jaeyeon (Center for Environmental Technology, Korea Institute of Science and Technology)
Park, Kyungsu (Advanced Analysis Center, Korea Institute of Science and Technology)
Kang, Inho (Herbal Medicine Evaluation Team, Korea Food and Drug Administration)
Kang, Sinjung (Herbal Medicine Evaluation Team, Korea Food and Drug Administration)
Kim, Yunje (Center for Environmental Technology, Korea Institute of Science and Technology)
Publication Information
Analytical Science and Technology / v.21, no.6, 2008 , pp. 480-486 More about this Journal
Abstract
This paper reports on the monitoring results of some heavy metals (Pb, Cd, As and Hg) in oriental mineral medicines. Levels of Pb, Cd and As were determined using the acid digestion method and ICP-MS. Hg levels were determined using the gold amalgamation method and Automatic mercury analyzer (AMA). The results indicated that, in the case of Pb, 25.81% (24 cases) of the samples were over MRL (5 mg/kg). Pb levels in Calamina, Pumex, and Cinnabaris exceeded MRL (5 mg/kg). In the case of Cd, 9.68% (17cases) of the samples were over MRL (0.3 mg/kg). Cd levels in Calamina, Pumex and Cinnabaris were exceeded MRL (0.3 mg/kg). In case of As, 24.73% (23 cases) of samples exceeded MRL (3 mg/kg). As levels in Calamina, Lithargyrum, Vermilionum, Cinnabaris and Chalcocitum exceeded MRL (3 mg/kg). In the case of Hg, it was shown that the 76.34% (78 cases) of the samples exceeded MRL (0.2 mg/kg). Hg levels in almost all the samples exceeded MRL (0.2 mg/kg). These results led us to recommend that the domestic commercial law to be legislated to ensure the quality estimation and safety of oriental mineral medicines.
Keywords
monitoring; four heavy metals (Pb, Cd, As, Hg); oriental mineral medicines; inductively coupled plasma-mass spectrometry; automatic mercury analyzer;
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  • Reference
1 E. D. Caldas and L. L. Machado, Food and Chemical Toxicology, 42, 599-603(2004)   DOI   ScienceOn
2 C.-G. Yuan, J.-B. Shi, B.-H. Liu, J.-F. Liang, L.-N. Liang and G.-B. Jiang, Environment International, 307, 69-783(2004)   DOI
3 A. M. O. Ajasa, M. O. Bello, A. O. Ibrahim, I. A. Ogunwande and N. O. Olawore, Food Chemistry, 85, 67-71(2004)   DOI   ScienceOn
4 E. Ernst, Pharmacological Sciences, 23, 136-139(2002)   DOI   ScienceOn
5 V. Rai, P. Kaffar, S. Khatoon, A. K. S. Rawat and S. Mehrotra, Pharmaceut. Biol. 39, 384-387(2001)   DOI   ScienceOn
6 V. Rai, M. Agarwal, Khatoon, A. K. S. Rawat and S. Mehrotra, Bull. Environ. Contam. Toxicol. 66, 427-432(2001)   DOI
7 P. W. Woods, Essence 30, 42-46(1999)
8 I. A. Khan, J. Allgood, L. A. Walker, E. A. Abourashed, D. Schelenk and W. H. Beson, J. AOAC International 84, 936-939(2001)
9 R. Chizzola and C. Franz, J. Appl. Bot. 70, 52-26(1996)
10 S. K. Srivastava, V. R. M. Srivastava, A. K. S. RAWAT and S. Mehrotra., Environmental Monitoring and Assessment, 116, 315-320(2006)   DOI
11 M. J. Stewart, J. J. Moar, P. Steenkamp and M. Kakot, Forensic Science International 101, 177-183(1999)   DOI   ScienceOn
12 G. Nordberg, Toxicology and Pharmacology, 30, S57-S62(1999)
13 S. Tong, von Y. E. Schirnding and T. Prapamontol, Bulletin of the World Health Organization 78, 1068-1077(2000)   PUBMED