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Kinetic Analysis by High Pressure and High Vacuum Apparatus for the Nucleophilic Substitution Reaction  

Kim, Se-Kyong (Department of Chemistry, Hanyang University)
Publication Information
Analytical Science and Technology / v.17, no.5, 2004 , pp. 375-380 More about this Journal
Abstract
Kinetics have been studied by high vacuum and high pressure apparatus under various temperatures and pressures for the nucleophilic substitution reaction. Rate constants, activated parameters and Hammett ${\rho}$-values are determined. The values of ${\Delta}V^{\ddag}$, ${\Delta}{\beta}^{\ddag}$ and ${\Delta}S^{\ddag}$ are all negative. The Hammett ${\rho}$-values are negative for the nucleophile (${\rho}x$) over the pressure range studied. Consequently the rate constant increases as the pressure increases, and some decrease in vacuum. So these reactions proceed in typical $S_N2$ reaction mechanism.
Keywords
high pressure; high vacuum; kinetics;
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