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Determination of alkylphenol ethoxylate in water by high performance liquid chromatography/electrospray ionization/mass spectrometry  

Lee, Jeongae (Bioanalysis & Biotransformation Research Center, Korea Institute Science & Technology)
Park, Song-Ja (Bioanalysis & Biotransformation Research Center, Korea Institute Science & Technology)
Chung, Bong Chul (Bioanalysis & Biotransformation Research Center, Korea Institute Science & Technology)
Publication Information
Analytical Science and Technology / v.17, no.3, 2004 , pp. 263-270 More about this Journal
Abstract
A method is described for the analysis of short-chain alkylphenol ethoxylates (APEOs), 4-octylphenol-di-ethoxylate (OP2EO) and 4-nonylphenol-di-ethoxylate (NP2EO), in drinking water or wastewater using reversed phase high-performance liquid chromatography with electrospray ionization mass spectrometry. The solvent system was water and methanol containing $10{\mu}M$ trifluoroacetic acid as an ionization solvent. We acidified 1 L of water samples to less than pH 2 with concentrated $H_2SO_4$ and loaded onto Sep-Pak $C_{18}$, and eluted with acetone. The calibration of OP2EO and NP2EO was performed for the concentration range from 20 to 500 ng/L and the correlation coefficients were 0.999 and 0.990, respectively. The limits of detection were 20 ng/L (OP2EO) and 50 ng/L (NP2EO) at a signal-to-noise ratio of 3. Accuracy and precision of this analytical method were 85.8 ~ 122.1% and 8.2 ~ 18.8%, respectively. The proposed method allowed a sensitive and rapid detection of OP2EO and NP2EO and it could be applied for monitoring of APEOs from environmental samples.
Keywords
alkylphenol ethoxylate; electrospray mass spectrometry;
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