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Residue and Risk Assessment of Polychlorinated dibenzo-p-dioxin/dibenzofurans in the Korean Population  

Kang, Youn-Seok (Lab Frontier Co. Ltd.)
Park, Jong-Sei (Lab Frontier Co. Ltd.)
Min, Byung-Yoon (Division of Civil and Environmental Engineering, Kyungnam University)
Publication Information
Analytical Science and Technology / v.15, no.3, 2002 , pp. 270-286 More about this Journal
Abstract
The human adipose and milk samples analyzed in this study were collected at hospitals in Seoul, Masan and Jinju. The mean values of International Dioxin Toxic Equivalents (I-TEQ) of PCDDs and PCDFs in human adipose samples from the three regions were calculated as 9 pg I-TEQ/g(0.2 ~ 30 pg TEQ/g, lipid weight basis) and 8 pg I-TEQ/g (0.8 ~ 25 pg TEQ/g), respectively. The residue levels of PCDDs-TEQ and PCDFs-TEQ in human milk collected from Masan were 13 pg I-TEQ/g (lipid wt.) and 4.8 pg I-TEQ/g, respectively. On the whole, the contamination levels of these compounds in the Korean population were lower than those in the other countries. Based on the analytical data and assuming a daily intake consumption of 800 mL milk with 3% fat, the average daily intake of PCDDs/DFs via human milk for a baby weighing 5 Kg could be calculated. The daily intake of PCDDs/DFs via breast-feeding was estimated to be 39 pg/kg body weight/day for 2,3,7,8-TeCDD and 86 pg/kg/day for TEQ. These levels are far above all virtually safe dose(VSD) or tolerable daily intake(TDI) values proposed by health authorities in various countries, ranging from 0.001(US EPA) to 4 pg/kag/day (WHO).
Keywords
PCDDs/DFs; organochlorine pesticides; PCBs; human adipose tissue; human milk;
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