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The Inclusion Complex Formation of Cyclodextrin and Congo Red in Aqueous Solution  

Kim, Chang Suk (School of Science Education, Chungbuk National University)
Kim, Dong Won (Department of Chemistry, Chungbuk National University)
Bahn, Woo Kyoung (Singal Middle School)
Publication Information
Analytical Science and Technology / v.15, no.2, 2002 , pp. 115-119 More about this Journal
Abstract
The formation of inclusion complexes between cyclodextrin(CD) and Congo red was studied by spectrophotometric methods at various temperatures. The cavity sizes are 0.49 nm, 0.62 nm for $\alpha$-and $\beta$-CD, respectively. Therefore, $\alpha$-CD was not found to form an inclusion complex with Congo red due to steric hinderance. In the $\beta$-CD use two $\beta$-CD molecules formed an inclusion complex with one molecule of Congo red, from the slope of the S-shaped curve increased. Two prominent isosbestic points appear at 346 nm and 478 nm. The formation constants were decreased with the increasing temperatures, due to low binding energy between $\beta$-CD and Congo red. The thermodynamic parameters were calculated from the plot of $lnK_f$ vs 1/T. The $\Delta$H, $\Delta$S and $\Delta$G were -50.73 kJ/mol, $-108.96J/K{\cdot}mol$ and -18.26 kJ/mol, respectively.
Keywords
host; guest; cyclodextrin; absorbance; inclusion complex; congo red;
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