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Incidence and Related Factors of the Metabolic Syndrome in a University Hospital  

Choi, Se-Mook (Graduate School of Public Health, Chungnam National University)
Kim, Keon-Yeop (Department of Preventive Medicine, School of Medicine, Kyungpook National University)
Lee, Tea-Yong (Department of Preventive Medicine, School of Medicine, Chungnam National University)
Jung, Jin-Gyu (Department of Family Medicine, Chungnam University Hospital)
Lee, Og-Kyoung (Department of Clinical Pathology, Deajeon Health Sciences College)
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Abstract
Objectives: The purpose of this research was to investigate incidence and related factors of the MS in a university hospital Methods: This survey was conducted from January in 1997 to March in 2008. This study is a cohort study. The baseline subjects were 529 men and 609 women without metabolic syndrome(MS) who visited the health promotion center of Chungnam National University Hospital for general health check-up. The MS was diagnosed according to the definition by the NCEP ATP III. The abdominal obesity guidelines for waist circumference applied the Korean Society for the Study of Obesity Guideline Results: The survey exhibited that baseline risk factors that mainly affect odds ratio(OR) of the MS at follow-up were sex, ages, heavy drinking, uric acid and transpeptidase(GGT) in women. Incidence of the MS was 10.6% in total cases, 18.1% in men and 4.0% in women. The risk of the MS was significantly lower in women than men(OR=0.4, 95% confidence interval(CI: 0.2-0.9), significantly higher 50-59 Ages than < 40 ages(OR=3.4, 95% CI: 1.9-6.4), significantly high in women with heavy drinkers(OR=14.3, 95% CI: 1.2-177.5), significantly high in whole, men and women with high uric acid group(whole, OR=2.6, 95% CI: 1.6-4.2. men, OR=2.1, 95% CI: 1.3-3.5. women, OR=14.2, 95% CI: 3.0-68.3) and significantly high in women with high GGT(OR=1.8, 95% CI: 2.4-12.6). Conclusion: Risk factors of incident MS were baseline sex, ages, heavy drinking in women, uric acid and GGT in women. These can be utilized as an important index to determine risk factors of incident MS and will be basic data in part of management, education, countermeasure and selection test of the MS.
Keywords
Metabolic syndrome; Incidence; Risk factor;
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1 Yoon YS, Oh SW, Baik HW, Park HS, Kim WY. Alcohol consumption and the metabolic syndrome in Korean adults: the 1998 Korean National Health and Nutritional Examination Survey. Am J Clin Nutr 2004;80(1):217-224   PUBMED
2 김서린 외 6명. 성인에서 대사증후군과 무증상 갑상샘저하증의 연관성. 2007 대한내분비학회 춘계학술대회 초록집 2007;2007(0):99
3 통계청. 국가통계포털 국내통계 주제별통계 보건사회복지 보건 사망원인. 2007, Available from: URL:http//www.kosis.kr
4 홍영습 외 6명. 일부 우리나라 성인의 대사성증후군의 유병률과 허리들레 예측치. 예방의학회지 2004;37(1):51-58
5 Ford ES. Leukocyte count, erythrocyte sekimentation rate, and diabetes incidence in a national sample of US adults. Am J Epidemiol 2002;155(1):57-64   DOI   PUBMED   ScienceOn
6 Nagahama K, Inoue T, Iseki K, Touma T, Kinjo K, Ohya Y, et al. Hyperuricemia as a predictor of hypertension in a screened cohot in Okinawa, Japan. Hypetens Res 2004;27(11):835-841   DOI   ScienceOn
7 Paul H, Lee DH, Michael S, Myron G, David R, Jacobs JR. Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome. JAMA 2008 May 21;299(19):2287-2293   DOI   ScienceOn
8 김성걸 외 8명. 혈청 요산 농도에 따른 대사증후군의 위험도. 가정의학회지 2007;28(6):428-435
9 윤원석, 이명숙, 유병철, 이용환. 말초혈액 내 백혈구 및 적혈구 수와 대사증후군의 연관성. 대한비만학회지 2007;16(4): 154-161
10 Balkau B, Vernay M, Mhamdi L, Novak M, Arondel D, Vol S, et al. The D.E.S.I.R. Study Group. The incidence and persistence of the NCEP(National Cholesterol Education Program) metabolic syndrome. The French D.E.S.I.R. study. Diabetes Metab 2003; 29(5):526-532   DOI   ScienceOn
11 남수민 외 6명. 한국 성인 남성에서 음주 및 간효소가 대사증후군의 유병률에 미치는 영향. 당뇨병 2007;31(3):253-260
12 정찬희, 박정식, 이원영, 김선우. 한국 성인에서 흡연, 음주, 운동, 교육정도 및 가족력이 대사증후군에 미치는 영향. 대한내과학회지 2002;63(6):649-659
13 이상엽 외 16명. 한국인의 복부비만 기준을 위한 허리둘레 분별점. 대한비만학회지 2006;15(1):1-9
14 이용제, 황의경, 김상원, 설재웅, 지선하. 흡연 정도에 따른 백혈구 수 증가와 고혈당증의 관계. 가정의학회지 2007;28(1):32-38
15 오현주 외 5명. 혈청 요산 농도와 대사증후군과의 관련성. 가정의학회지 2006;27(9):699-705
16 임열리 외 5명. ATP III 의 진단기준에 따른 대사증후군의 유병률과 관련위험요인 분석. 가정의학회지 2003;24(2):135-143
17 홍원기 외 6명. 여성 음주와 대사증후군. 가정의학회지 2007;28(2):120-126
18 진호준, 나기영, 김연수, 채동완, 김성권. 한국인에서 고요산혈증 및 대사 증후군이 고혈압의 발생에 미치는 영향. 대한내과학회지 2007;73(1):58-66
19 김종성. 알코올 중독의 진단과 치료. 가정의학회지 2004;25(11):Suppl. 256-265
20 Tuomilehto J, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, et al. Prevention of type 2 diabetes melitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001;344(18):1343-1350   DOI   ScienceOn
21 보건복지부. 1995년 국민건강․영양조사. 1997
22 Alper AB Jr, Chen W, Yau L, Srinivasan SR, Berenson GS, Hamm LL. Childhood uric acid predicts adult blood pressure. Hypertension 2005;45(1):34-38   PUBMED
23 US Department of Agriculture. The report of the dietary guidelines advisory committee on dietary guidelines for Americans, 2005. USA: Department of Agriculture 2005
24 박정식 외 5명. 도시지역 검진 수진자 40,698명에서 NCEP-ATP Ⅲ 기준에 의한 대사증후군의 유병율. Korean J Intern Med 2002;63(3):290-98
25 보건복지부. 2007년 보건복지통계연보. 2007
26 Jianjun W, Sanna R, Leena M, Paivi L, Markku L, Johanna K. The metabolic syndrome predicts incident stroke: A 14-year followup in elderly people in Finland. Stroke 2008;39(3):1078-1083
27 Vozarova B, Weyer C, Lindsay RS, Pratley RE, Bogardus C, Tataranni PA. High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 2002;51(2):455-461   PUBMED
28 정찬희 외 8명. 정상 갑상선 기능을 보이는 일반 성인에서 갑상선 기능과 대사증후군과의 연관성. 2007 대한내분비학회 춘계학술대회 초록집 2007;2007(0):126
29 이미영 외 7명. 혈청 감마지티(gamma-glutamyltransferase)와 당뇨병 유병률과의 상관관계. 대한내과학회지 2004;67(5):498-505
30 Groop L, Ortho-Melander M. The dysmetabolic syndrome. J Internal Med 2001;250(2):105-120   DOI   ScienceOn
31 World Health Organization West Pacific Region Office. The Asia-Pacific perspective: refining obesity and its treatment. IOTF Feb. 2000
32 권혁상 외 10명. 한국성인에서의 NCEP-ATP 3 기준을 적용한 대사증후군 유병률과 임상적 특징. 대한내과학회지 2005;68(4):359-368
33 Jacqueline MD, Cynthia G, Thomas R, Giel N, Coen DS, Lex MB, et al. Metabolic syndrome and 10-year cardiovascular disease risk in the Hoorn Study. Circulation 2005;112(5):666-673   DOI   ScienceOn
34 Leoncini G, Ratto E, Viazzi F, Vaccaro V, Parodi D, Parodi A, et al. Metabolic syndrome is associated with early signs of organ damage in nondiabetic, hypertensive patients. J Intern Med 2005;257(5):454-460   DOI   ScienceOn
35 박혜순 외 8명. 한국인에서 대사증후군의 유병률 및 관련 요인 -1998년 국민건강영양조사를 바탕으로-. 대한비만학회지 2003;12(1):1-14
36 Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001;285(19):2486-2497   DOI   PUBMED   ScienceOn
37 Peter TK, Robert R, Timothy SC, Steven NB, Ian J. Metabolic syndrome, obesity, and mortality. Diabetes Care 2005;28(2): 391-397   DOI   ScienceOn