In this study, we investigated the effects of extrusion ratio and extrusion temperature on the microstructure and tensile properties of extruded Mg-6Al-0.3Mn-0.3Ca-0.2Y (SEN6) alloy. As the extrusion ratio and temperature increase, dynamic recrystallization during extrusion is promoted, leading to the formation of a fully recrystallized microstructure with increased grain size. Additionally, the increases in extrusion ratio and temperature lead to texture strengthening, exhibiting a higher maximum texture intensity. The extruded materials contain three types of secondary phases, i.e., Al8Mn4Y, Al2Y, and Al2Ca, with irregular or polygonal shapes. The quantity, size, distribution, and area fraction of the second-phase particles are nearly identical between the two materials. Despite its larger grain size, the tensile yield strength of the material extruded at 450 ℃ and an extrusion ratio of 25 (450-25) is higher than that of the material extruded at 325 ℃ and an extrusion ratio of 10 (325-10), which is mainly attributed to the stronger texture hardening effect of the former. The ultimate tensile strength is similar in the two materials, owing to the higher work hardening rate in the 325-10 extrudate. Despite differences in grain size and recrystallization fraction, numerous twins are formed throughout the specimen during tensile deformation in both materials; consequently, the two materials exhibit nearly the same tensile elongation.