Objectives : Many researches have studied warm needling technique to standardize its treatment by temperature measurement and material differences in the effectiveness. The purpose of this study is to compare the temperature changes of the acupuncture needle shaft during the combustion process of the moxa stick to determine the heat transfer pattern of the warn needling. Methods : A moxa stick($7{\times}8mm$) was connected to one side of the needle shaft using a stainless steel needle(ø 0.3 mm, ø 0.5 mm, ø 0.8 mm, shaft length 40 mm) with the needle handle removed. During the warm needling, temperature changes of the needle shaft were observed with an infrared camera(Flir E30) and an infrared thermometer(TESTO 845). Results : In the normal condition, heat transmit of needle shaft increased at spots 10 mm and 25 mm below the moxa stick. The amount of heat transmit increased with the diameter of needle shaft. However, when the heat shield was installed to exclude radiant heat from the moxa stick, heat transfer was less at 10 mm below the moxa stick and no temperature change was observed at 25 mm below the moxa stick. Heat transfer by warm needling does not reach the end of needle shaft even in ø 0.8 mm needle. Conclusions : It is suggested that the radiant heat of moxa stick results in the heat transmit of acupuncture needle shaft. Thus, radiant heat transmit must be considered as one of the heat transfer characteristics of the warm needling.

Objectives : The aim of this study was to assess the effectiveness of acupuncture in treating prehypertension and stage 1 hypertension in postmenopausal women. Methods : The study was a multi-center, four-arm, non-blinded, randomized clinical trial. Sixty participants were randomly assigned to experimental or control groups. The experimental groups received 10 acupuncture sessions over 4 weeks(Group A, n=20) or 20 sessions over 8 weeks(Group B, n=20) along with usual care. The acupoints were GB20, LI11, ST36, and SP6, bilaterally. The acupuncture groups were followed-up for an additional 12 weeks after acupuncture treatment. The control groups received usual care for 16 weeks(Group C, n=10) or 20 weeks(Group D, n=10). The outcomes were blood pressure, blood pressure control rates, lipid profile, and high-sensitivity C-reactive protein(hs-CRP). Results : After 4 weeks, DBP in the acupuncture groups(A+B) showed no significant decrease compared to the control group(C+D). However, after 8 weeks of acupuncture treatment, group B showed a significant decrease in DBP after acupuncture treatment and follow-up period compared to control group. Although there was no difference between the acupuncture and control groups in SBP after acupuncture treatment, group B showed a significant decrease in SBP compared to control group after follow-up period. Lipid profiles and hs-CRP did not differ significantly between acupuncture and control groups. Conclusions : Acupuncture treatment for 8 weeks showed the effect on prehypertension and mild hypertension. To verify the effect of acupuncture on blood pressure, rigorous trials including more participants are required.

Objectives : The purpose of this study was to describe the type of claimed adverse events related to Korean Medicine practices in South Korea. Methods : Claims with regard to the Korean Medicine practice submitted to the Korea Medical Dispute Mediation and Arbitration Agency from April 2012 to December 2016 were collected. We analyzed claims that explicitly reported the type of Korean medicine intervention and were deemed as being adverse events as defined by the Korea Good Clinical Practice. Claims that did not mention the Korean medicine practice explicitly or those related to the patient's dissatisfaction to the service rather than adverse health outcomes were excluded. Types, related interventions and the suspected severity of claimed adverse events were summarized. Results : Of 197 claims obtained, 140 claim cases were eligible and 144 claimed events were deemed as possible adverse events of the Korean medicine practice. Pain(16%), local infection/inflammation(12%) and neurological symptoms(11%) were the most frequently reported types of claimed adverse events. Thirty-nine claimed serious adverse events(SAE) were identified, including pneumothorax(28.2%) and death(17.9%). Conclusions : A wide range of claimed adverse events were identified. Routine monitoring of claims data may provide undetected safety information with regard to the Korean medicine practice. High risk of misclassification of the intervention and claimed adverse events due to insufficient information is the main caveat of this study.

Objectives : Previous research on texts specializing in acupuncture and moxibustion in Korea have mostly been focused on those written in the Joseon period, leaving an academic void in the modern and contemporary eras. This research on the "Yeongsochimgugyeong" was undertaken to help readers' understanding of the text and to provide basic material for further research on modern-contemporary education of acupuncture and moxibustion. Methods : The original text of "Yeongsochimgugyeong" was examined along with books and news articles on related people. Information that was difficult to obtain through written documents was supplemented by interviews with people who knew about the situation at the time. The findings were organized as 1) the author and related people and 2) introduction of "Yeongsochimgugyeong". Results and Conclusions : The original text of "Yeongsochimgugyeong" was written by teacher Jeon, Gwangok, interpreted and annotated by his disciple Gwon, Yeongjun. It is presumed that they wrote this book as educators of Korean medicine for educational purposes on acupuncture and moxibustion before and after the Japanese colonial era. The book is consisted of an overview of meridianology, details on points and meridians, supplementing and draining methods, similar to the current text book. The contents and expressions of "Yeongsochimgugyeong" reflect the state of acupuncture and moxibustion education of the early and mid $20^{th}$ century, making it a valuable resource.

Objectives : This study was carried out to investigate the effects of Crataegi Fructus water extract(CFWE) on hair growth in an alopecia model of C57BL/6N mice and human dermal papilla cells(hDPCs). Methods : Six-week old mice were depilated and separated in 3 groups ; CON, MXD(2% Minoxidil), and CFWE. The treatments were applied twice a day for 18 days. The hair growth was determined photographically. The hair density, thickness and length were identified by Folliscope and the weights of body were measured. In dorsal skin tissue, the expression of hair growth-related protein was analyzed by Western blot. In hDPCs with/without $IFN-{\gamma}$, cell proliferation and the expression of hair growth-related genes were analyzed. Results : We observed that CFWE promoted hair growth compared to CON. CFWE improved the hair density, thickness and length compared to CON. CFWE increased the $Wnt/{\beta}$-catenin signaling in dorsal skin. In hDPCs, CFWE accelerated the cell proliferation and inhibited $IFN-{\gamma}$-induced hDPCs degeneration. CFWE increased the mRNA expression of ${\beta}$-catenin, Axin-2, BMP-4, FGF-7, FGF-10, and ALP compared to CON and $IFN-{\gamma}$ treated cells. Conclusions : These results suggest that CFWE has a hair regrowth activity via $Wnt/{\beta}$-catenin signaling and can be useful for the treatment of alopecia.

Objectives : The purpose of this study is to evaluate the effects of Korean Medicine in two patients with oculomotor nerve palsy. Methods : Acupuncture was inserted into left Sojangjungkyuk(BL66, SI2, GB41 and SI3) for 15 minutes in multiple visits. Also, two kinds of herbal medicine, Gaejigeogaegayoungchul-tang and Younggaekamjo-tang were given to each patient. Results : After the treatment, patient's main symptoms were improved. Conclusions : We suggest that especially Sojangjungkyuk-based Korean Medical treatment may be effective for improvement of oculomotor nerve palsy.

목적 : 본 연구는 음허로 인한 야간발열 환자 2명에 대한 동씨침의 영골 및 대백혈의 치료효과를 알아보고, 이를 경락학적으로 고찰하는데 목적이 있다. 방법 : 음허로 진단된 2명의 환자를 대상으로 영골 및 대백혈에 침 치료를 시행하고, 15분 간 유침하였으며, 치료 전 후에 체온과 맥박을 측정하고, 구갈에 관한 NRS를 치료전에 측정하였다. 결과 : 영골 및 대백혈 자침 1시간 후 체온이 두명의 환자 모두 정상범위로 하강하였으며, Case 1의 경우는 영골 및 대백혈 자침치료를 시작한지 13일후, Case 2의 경우에는 14일 후에 야간발열 증상이 소실되었다. 11 pm에 측정한 맥박수는 Case 1에서 침 치료 시작 전 평균 82.6에서 치료 기간 중에는 75.2, 치료 후 74.8로 변화하였고, Case 2에서는 침 치료 시작전 평균 83.5에서 치료 기간 중에는 78.5, 치료 후 74.3으로 변화하였다. NRS는 Case 1에서 치료 전 평균 4.2에서 치료 기간 중에는 3.2, 치료 후 1.7로 감소하였으나 Case 2에서는 치료 전 평균 3.3에서 치료 기간 중에는 2.3, 치료 후 2.4로 변화하였다. 결론 : 두 가지 Case에서 영골 및 대백혈 자침은 발열증상을 완화하는데 효과적이었다. 이는 영골 및 대백혈이 수양명대장경의 경락 및 경근이 분포하는 영역에 위치하고 있기 때문에 수양명대장경의 열성병 치료효과와 대장주진의 생리학적 관점에서 고찰해 볼 수 있으며, 앞으로 이와 관련한 체계적이고 다양한 연구가 필요하리라 사료된다.

Objectives : The purpose of this study is to report a case of traditional Korean Medicine effect on a patient with rhabdomyolysis who appealed leg pain, numbness and weakness. Methods : A patient received traditional Korean Medicine including acupuncture, herbal medicine, moxibustion, and cupping therapy daily. We evaluated the clinical results by observing the patient's symptoms, NRS(Numerical Rating Scale), MMT(Manual Muscle Test) grade and DITI(Digital Infrared Thermal Imaging). Results : After traditional Korean Medicine, the patient's pain and numbness decreased from NRS 10 to 1~2 and weakness improved from Gr3- to Gr4. And CPK(creatine phosphokinase) numerical value decreased from 330(IU/L) to 164 and body heat status improved. Conclusions : Traditional Korean Medicine can be effective in reducing rhabdomyolysis patients' symptoms and changing examination numerical value. And further studies on traditional Korean Medicine of rhabdomyolysis should be carried out.

목적 : 안면 비대칭에 대한 한의학적 치료의 적용가능성에도 불구하고, 아직까지 관련 연구는 보고되지 않고 있다. 이 증례보고에서 저자들은 하악골 측방변위로 인한 안면 비대칭에 대하여 한의학적 치료의 효과와 안전성을 보고하였다. 방법 : 3명의 안면 비대칭 환자가 동작침법, 기능적 뇌척주요법의 음양균형장치, 연부조직이완술로 구성된 한의학적 치료를 12회 받았다. 치료 전후에 환자의 사진이 촬영되었다. 치료 전후의 4개의 주요 기준선의 변화가 평가되었다. 결과: 모든 환자들은 사진상의 호전을 보였다. 하지만 통계적으로 유의한 차이는 없었다. 결론 : 이 증례보고는 안면 비대칭에 대해 한의학적 치료의 효과를 보고하는 첫 번째 보고이다. 추후 이러한 결과를 확인하기 위한 더 잘 설계된, 무작위화, 플라세보 대조 연구가 필요하다.