This study aims to develop an improved evaluation technology for assessing CANDU-6 safety. For this purpose, the multiple steam generator tube rupture (mSGTR) followed by an unmitigated station blackout (SBO) in a CANDU-6 plant was selected as a hypothetical event scenario and the analysis model to evaluate the plant responses was envisioned into the MARS-KS input model. The model includes logic models for controlling the pressure and inventory of the primary heat transport system (PHTS) decreasing due to the u-tubes' rupture, as well as the main features of PHTS with a simplified model for the horizontal fuel channels, the secondary heat transport system including the shell side of steam generators, feedwater and main steam line, and moderator system. A steady state condition was successfully achieved to confirm the stable convergence of the key parameters. Until the turbine trip, the fuel channels were adequately cooled by forced circulation of coolant and supply of main feedwater. However, due to the continuous reduction of PHTS pressure and inventory, the reactor and turbine were shut down and the thermal-hydraulic behaviors between intact and broken loops got asymmetric. Furthermore, as the conditions of low-flow coolant and high void fraction in the broken loop persisted, leading to degradation of decay heat removal, it was evaluated that the peak cladding temperature (PCT) exceeded the limit criteria for ensuring nuclear fuel integrity. This study is expected to provide the technical bases to the accident management strategy for transient conditions with multiple events.