Purpose: This study was done to examine factors influencing cell phone addiction for middle school students by gender. Methods: The participants were 228 male students and 228 female students in two middle schools. Data were collected through self-report questionnaires, and analyzed using the SPSS/WIN 19.0 program. Results: Cell phone addictions of female students are higher than those of male students. Factors influencing cell phone addiction for male students were mimicry, sending text message on weekdays, immediate self-control, grade, syntony, and monthly call charge, explaining 42.2% of variance in cell phone addiction. Factors influencing cell phone addiction for female students were internet addiction, sending and receiving text message on weekends, immediate self-control, long-term self-control, use time, main use, syntony, and monthly call charge, explaining 46.8% of variance in cell phone addiction. Conclusion: The results indicated that cell phone addiction and its influencing factors differed by gender. Therefore the approach to effective cell phone addiction management program for middle school students should consider gender differences.