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A Case of Hemorrhagic Transformation with Motor and Language Impairments Treated with Korean Medicine, including Modified Geopoongjaeseup-tang (Modified Qufeng Chushi Decoction): Case Report

거풍제습탕가미(Modified Qufeng Chushi Decoction)를 포함한 한의 복합치료로 운동장애 및 언어장애를 동반한 출혈성 변환 환자를 치료한 사례 : 증례보고

  • Jeong-rim Bak (Dept. of Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Jungtae Leem (Research Center of Traditional Korean Medicine, Wonkwang University) ;
  • Ji-hyun Hwang (Dept. of Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Gwan-hun Kim (Dept. of Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Chiho Choi (Dept. of Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Su-won Yu (Dept. of Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Hyo-won Jin (Dept. of Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Jong-min Yun (Dept. of Internal Medicine, College of Oriental Medicine, Wonkwang University)
  • 박정림 (원광대학교 한의과대학 내과학교실) ;
  • 임정태 (원광대학교 한국전통의학연구소) ;
  • 황지현 (원광대학교 한의과대학 내과학교실) ;
  • 김관훈 (원광대학교 한의과대학 내과학교실) ;
  • 최치호 (원광대학교 한의과대학 내과학교실) ;
  • 유수원 (원광대학교 한의과대학 내과학교실) ;
  • 진효원 (원광대학교 한의과대학 내과학교실) ;
  • 윤종민 (원광대학교 한의과대학 내과학교실)
  • Received : 2024.09.11
  • Accepted : 2024.10.23
  • Published : 2024.10.30

Abstract

Objective: The purpose of this study was to report the clinical course of complex Korean medicine to treat a patient with hemorrhagic transformation following cerebral infarction. Case presentation: A 46-year-old Korean male was hospitalized with cerebral infarction followed by hemorrhagic transformation classified as parenchymal hematoma type 2. Based on the symptoms and condition, the pattern identification of the patient was deficiency of qi and retention of fluid (Qi-xu, Tan-yin). The patient was treated with herbal medicine, acupuncture, and rehabilitation programs for 187 days. The herbal medicine consisted of modified Geopoongjaeseup-tang (modified Qufeng Chushi decoction) for the first 62 days, followed by another modified Geopoongjaeseup-tang for the next 76 days, and finally Gagamyoonjo-tang (Jiajian Runzao decoction) for the last 30 days, administered 3 times a day. After 187 days, the functional independence measure and modified Barthel index improved (from 75 to 100 and from 44 to 84, respectively), and the MMT of the right upper and lower extremities also improved (from 2+ to 3+ and from 3+ to 4, respectively). In particular, right finger flexion improved from 1 to 3- and right ankle and greater toe improved from 1+ to 4. There were no reports of adverse effects of the treatment. Conclusion: The results suggest that complex Korean medicine treatment for motor and language impairments caused by parenchymal hematoma type 2 hemorrhagic transformation may be effective in improving functions for daily living. Further studies should be conducted with a larger number of patients.

Keywords

Acknowledgement

This research was supported by the Bio & Medical Technology Development Program of the National Research Foundation (NRF) funded by the Korean government (MSIT) (No. RS-2023-00261934). This research was also supported by a grant of the Korea Health Technology Project through the Korea Health Industry Development Institute, funded by the Ministry of Health and Welfare, Republic of Korea (grant no. RS-2023-KH139333).

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