Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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An Assessment of Thoracic Inlet Heart Score in Maltese Dogs with ACVIM Stage B Myxomatous Mitral Valve Disease

  • Received : 2024.07.29
  • Accepted : 2024.09.15
  • Published : 2024.10.31
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Abstract

Myxomatous mitral valve disease (MMVD) is the most common cardiac disease in dogs. Vertebral heart score (VHS) is used for the diagnosis, treatment, and monitoring of MMVD, and it is one of the criteria used to distinguish between stages B1 and B2 according to the American College of Veterinary Internal Medicine (ACVIM) guidelines. The thoracic inlet heart score (TIHS) method is simple to perform and provides practitioners with an additional tool for evaluating dogs with clinical signs compatible with MMVD stage B. Previous studies have evaluated TIHS. In our study, we assessed correlations of TIHS with other radiographic and echocardiographic indices in Maltese dogs with MMVD stages B1 and B2. Eighty-seven Maltese dogs with MMVD stage B1 or B2, which visited Chungnam National University Veterinary Medicine Teaching Hospital, were included in this study. Each dog was diagnosed with MMVD ACVIM stage B1 or B2 through physical examination, cardiac auscultation, thoracic radiography, and echocardiography, with evaluation of TIHS, VHS, vertebral left atrial size (VLAS), left atrial to the aotic root ratio (LA:Ao ratio), and left ventricular internal diameter in diastole, normalized for body weight (LVIDDn). TIHS increased as the disease progressed and showed a significant difference between stages B1 and B2. Furthermore, TIHS positively correlated with VHS, LA:Ao ratio, and LVIDDn. The correlation coefficients revealed the strongest significant correlations between TIHS and VHS. In conclusion, TIHS can help diagnose and monitor MMVD in Maltese dogs, in addition to measuring VHS.

Keywords

Acknowledgement

This research was funded by the Rural Development Administration, South Korea (grant number RS-2023-00231965).

References

  1. Buchanan JW, Bucheler J. Vertebral scale system to measure canine heart size in radiographs. J Am Vet Med Assoc 1995; 206: 194-199.
  2. Fox PR. Pathology of myxomatous mitral valve disease in the dog. J Vet Cardiol 2012; 14: 103-126.
  3. Hansson K, Haggstrom J, Kvart C, Lord P. Interobserver variability of vertebral heart size measurements in dogs with normal and enlarged hearts. Vet Radiol Ultrasound 2005; 46: 122-130.
  4. Hollmer M, Willesen JL, Tolver A, Koch J. Left atrial volume and function in dogs with naturally occurring myxomatous mitral valve disease. J Vet Cardiol 2017; 19: 24-34.
  5. Jepsen-Grant K, Pollard RE, Johnson LR. Vertebral heart scores in eight dog breeds. Vet Radiol Ultrasound 2013; 54: 3-8.
  6. Keene BW, Atkins CE, Bonagura JD, Fox PR, Haggstrom J, Fuentes VL, et al. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. J Vet Intern Med 2019; 33: 1127-1140.
  7. Lam C, Gavaghan BJ, Meyers FE. Radiographic quantification of left atrial size in dogs with myxomatous mitral valve disease. J Vet Intern Med 2021; 35: 747-754.
  8. Lee CM, Song DW, Ro WB, Kang MH, Park HM. Genome-wide association study of degenerative mitral valve disease in Maltese dogs. J Vet Sci 2019; 20: 63-71.
  9. Lord PF, Hansson K, Carnabuci C, Kvart C, Haggstrom J. Radiographic heart size and its rate of increase as tests for onset of congestive heart failure in Cavalier King Charles Spaniels with mitral valve regurgitation. J Vet Intern Med 2011; 25: 1312-1919.
  10. Malcolm EL, Visser LC, Phillips KL, Johnson LR. Diagnostic value of vertebral left atrial size as determined from thoracic radiographs for assessment of left atrial size in dogs with myxomatous mitral valve disease. J Am Vet Med Assoc 2018; 253: 1038-1045.
  11. Marbella Fernandez D, Garcia V, Santana AJ, Montoya-Alonso JA. The thoracic inlet heart size, a new approach to radiographic cardiac measurement. Animals (Basel) 2023; 13: 389.
  12. Marbella Fernandez D, Garcia V, Santana AJ, Montoya-Alonso JA. The thoracic inlet length as a reference point to radiographically assess cardiac enlargement in dogs with myxomatous mitral valve disease. Animals (Basel) 2023; 13: 2666.