Development and Reproduction (한국발생생물학회지:발생과생식)

The Korean Society of Developmental Biology (한국발생생물학회)
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Banana Peel Extracts Enhance Climbing Ability and Extend Lifespan in Drosophila melanogaster

  • Hyejin Seo (School of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University) ;
  • Jong-Won Yoon (School of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University) ;
  • Younghwi Kwon (KNU-G LAMP Research Center, KNU-Institute of Basic Sciences, School of Life Sciences, College of Natural Sciences, Kyungpook National University) ;
  • Eunbyul Yeom (School of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University)
  • Received : 2024.06.28
  • Accepted : 2024.08.24
  • Published : 2024.09.30
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Abstract

Banana peels, often discarded as waste, represent one of the most abundant food by-products, highlighting the need for effective waste management and resource recycling strategies. Due to their rich nutritional content, banana peels have been investigated for various health benefits, including anti-obesity effects. In this study, we examined the potential anti-aging properties of banana peel extracts (BPEs) in Drosophila melanogaster. Our findings demonstrated that flies fed with BPEs exhibited an extended lifespan and a significant improvement in age-related decline in climbing ability. Additionally, Dilp2 mRNA expression level is markedly decreased in aged flies fed with BPEs. These results suggest that BPEs may serve as a potential anti-aging agent by enhancing locomotor function and extending lifespan, potentially through the modulation of insulin signaling in D. melanogaster.

Keywords

Acknowledgement

This study was supported by the National Research Foundation of Korea (2022R1C1C100636712), and Global - Learning & Academic research institution for Master's·PhD students, and Postdocs (G-LAMP) Program of the National Research Foundation of Korea (NRF) grant funded by the Ministry of Education (No. RS-2023-00301914).

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