Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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The Therapeutic Effect of Mindfulness-Based Interventions on Depressive Symptoms in Patients With Major Depressive Disorder: A Meta-Analysis

주요우울장애 환자의 우울증상에 대한 마음챙김 기반의 치료적 개입의 효과에 관한 메타분석

  • Hannui Park (Department of Psychiatry, Kangwon National University School of Medicine) ;
  • Seyeon Hong (Department of Neuropsychiatry, Presbyterian Medical Center) ;
  • Euihyeon Na (Department of Neuropsychiatry, Presbyterian Medical Center) ;
  • Myoung-Nam Lim (Biomedical Research Institute, Kangwon National University Hospital) ;
  • Kanguk Lee (Department of Psychiatry, Kangwon National University School of Medicine)
  • 박한뉘 (강원대학교병원 정신건강의학과) ;
  • 홍세연 (예수병원 정신건강의학과) ;
  • 나의현 (예수병원 정신건강의학과) ;
  • 임명남 (강원대학교병원 의생명연구원) ;
  • 이강욱 (강원대학교병원 정신건강의학과)
  • Received : 2023.10.27
  • Accepted : 2024.02.27
  • Published : 2024.04.30
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Abstract

Objectives We conducted a meta-analysis of randomized controlled trials to investigate the therapeutic effects of mindfulness-based interventions on depressive symptoms in patients with major depressive disorder. Methods In February 2021, we searched Embase, MEDLINE, Cochrane Library, PsycINFO, CINAHL, and AMED. Under the guidance of the corresponding author, two evaluators independently reviewed and selected articles based on predetermined selection criteria. Results Based on the selection criteria, we systematically screened and included a total of 12 randomized controlled trials comprising 720 cases for the final analysis. Utilizing a random-effects model for data analysis, we determined the Hedges' g value to be 0.787, indicating a medium-sized effect according to Cohen's interpretation. The 95% confidence interval for the effect size ranged from 0.414 to 1.160 (p-value < 0.0001). Conclusions This study reveals the potential effectiveness of mindfulness-based interventions in treating depressive symptoms among patients with major depressive disorder.

Keywords

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