Nuclear Engineering and Technology

  • 제56권6호
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  • Pages.2247-2257
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  • 2024
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  • 1738-5733(pISSN)
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  • 2234-358X(eISSN)
한국원자력학회 (Korean Nuclear Society)
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Implication of ICRP pediatric reference voxel phantoms on dose assessment of patients in radioiodine therapy

  • Soo Min Lee (Department of Radiation Convergence Engineering, Yonsei University) ;
  • Chansoo Choi (J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida) ;
  • Ji Won Choi (Department of Radiation Convergence Engineering, Yonsei University) ;
  • Chul Hee Min (Department of Radiation Convergence Engineering, Yonsei University) ;
  • Seulki Ko (Department of Preventive Medicine, Eulji University School of Medicine) ;
  • Bangho Shin (Department of Nuclear Engineering, Hanyang University) ;
  • Chan Hyeong Kim (Department of Nuclear Engineering, Hanyang University) ;
  • Yeon Soo Yeom (Department of Radiation Convergence Engineering, Yonsei University)
  • 투고 : 2023.11.15
  • 심사 : 2024.01.23
  • 발행 : 2024.06.25
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초록

To investigate the impact of the recently released pediatric reference voxel phantoms (0-, 1-, 5-, 10-, 15-year-old males and females) of the International Commission on Radiological Protection (ICRP) on organ dose estimates for radioactive iodine (RAI) treatment in pediatric patients, we calculated and analyzed pediatric-specific iodine131 S values (rT ← thyroid) for the 30 radiosensitive organs by conducting Monte Carlo simulations using the Geant4. The gender dependency in the S values was frequently seen for the 15-year-old phantoms with higher S values of female than male. In addition, the age dependency in the S values was observed for most target organs; that is, the S values tend to decrease for older ages (e.g., ~120 times for the gonads between the adult and newborn) due mainly to the inter-organ distances generally longer for older ages. Moreover, we observed that the iodine-131 S values tend to be significantly greater by up to ~145.5 times than those of the stylized phantoms that have been widely used for organ dose estimates of pediatric RAI patients. We believe that the pediatric-specific iodine-131 S values (rT ← thyroid) of the ICRP pediatric reference voxel phantoms should be beneficial to improve the dosimetry of pediatric RAI patients.

키워드

과제정보

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (No. 2022R1C1C100809312 and No. RS-2023-00210289), the Nuclear Safety Research and Development (NSR&D) Program through the Korea Foundation of Nuclear Safety (KoFONS) funded by the Nuclear Safety and Security Commission (NSSC) (Project No. 2203028), Regional Innovation Strategy (RIS) through the NRF funded by the Ministry of Education (MOE) (No. 2022RIS-005), and Korea Institute of Energy Technology Evaluation and Planning (KETEP) and the Ministry of Trade, Industry & Energy (MOTIE) of the Republic of Korea (No. 20214000000070).

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