Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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A Study on the Antimicrobial Activity of Snowberry Extract

스노우베리 추출물의 항균 활성에 관한 연구

  • Chanwoo Lee (Miglim Co., Ltd) ;
  • Hye-Yeon Heo (Dept. of Cosmetics Engineering, College of Technology Sciences. Mokwon University) ;
  • Yu-Jin Park (Dept. of Cosmetics Engineering, College of Technology Sciences. Mokwon University) ;
  • YoungPyo Jang (College of Pharmacy, Kyung Hee University) ;
  • Bo Ae Kim (Dept. of Cosmetics Engineering, College of Technology Sciences. Mokwon University)
  • 이찬우 (미그림) ;
  • 허혜연 (목원대학교 화장품공학과) ;
  • 박유진 (목원대학교 화장품공학과) ;
  • 장영표 (경희대학교 약학대학) ;
  • 김보애 (목원대학교 화장품공학과)
  • Received : 2023.12.27
  • Accepted : 2024.04.18
  • Published : 2024.04.30
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Abstract

This study compared and evaluated the antibacterial activities and MIC of snowberry extract and fermented extract. For antibacterial activity, Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Escherichia coli, and Candida Albicans were used. Antimicrobial activity and MIC were measured at concentrations of 10, 50, 100, and 200 mg/mL. Antibacterial activity was measured using the 8mm paper disc method. In the case of snowberry extract, it was confirmed that the root extract showed antimicrobial activity at concentrations of 100 mg/mL and 200 mg/mL, and in the case of fermented extract, it showed antimicrobial activity at 200 mg/mL. As a result of the MIC, for fermentation in snowberry leaf and root extracts, the minimum inhibitory concentration for each bacterium was confirmed in stem extracts. The above results indicate that the antibacterial properties of snow berries are improved by fermentation.

본 연구는 스노우베리 추출물과 발효 추출물을 대상으로 피부 상재균인 Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans를 이용하여 천연화장품 소재로서의 항균 활성을 비교 평가하였다. 이를 위한 스노우베리 추출물의 항균 활성은 10-200mg/mL 농도에서 생육저해환(paper disc diffusion method)과 최소저해농도(Minimum inhibitory concentration)를 평가하였다. 스노우베리 추출물과 발효 추출물의 생육저해환을 확인하였을 때, 스노우베리 추출물의 경우 뿌리 추출물에서만 100mg/mL, 200mg/mL의 농도에서 항균력을 나타내었고, 발효 추출물의 경우 200mg/mL에서 항균력을 나타내는 것을 확인하였다. 그러나 스노우베리 추출물과 발효 추출물의 4종의 세균에 대한 항균력은 확인할 수 있었으나, 진균인 Candida albicans에서는 항균력을 확인할 수 없었다. MIC 결과 스노우베리 잎, 뿌리 추출물에서 발효의 경우 줄기 추출물에서 각 균에 대한 최소저해농도가 100mg/mL, 200mg/mL로 확인되었다. 이러한 결과는 스노우베리가 피부 개선을 위한 항균 소재 및 방부제로서의 활용 가치가 있다고 사료된다.

Keywords

Acknowledgement

본 성과물(논문)은 농촌진흥청에서 시행한 농업실용화기술R&D지원사업(과제번호: RS-2023-00215852)의 지원에 의해 이루어진 것임.

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