The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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A Case Report of Integrative Treatment in a Type 2 Diabetes Patient with Multiple Symptoms and Evaluation Using Continuous Glucose Monitoring

소갈 증상을 호소하는 제2형 당뇨 환자에서의 한양방 병행치료 치험 1례와 연속 혈당 측정기를 이용한 평가

  • Woo-nyoung Jung (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Mee-ryoung Song (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Yeon-joo Yoo (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Min-seong Lee (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Young-min Ahn (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Se-young Ahn (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Byung-cheol Lee (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University)
  • 정우녕 (경희대학교 대학원 임상한의학과) ;
  • 송미령 (경희대학교 한의과대학 부속병원 신장내분비내과교실) ;
  • 유연주 (경희대학교 한의과대학 부속병원 신장내분비내과교실) ;
  • 이민승 (경희대학교 한의과대학 부속병원 신장내분비내과교실) ;
  • 안영민 (경희대학교 한의과대학 부속병원 신장내분비내과교실) ;
  • 안세영 (경희대학교 한의과대학 부속병원 신장내분비내과교실) ;
  • 이병철 (경희대학교 한의과대학 부속병원 신장내분비내과교실)
  • Received : 2024.04.28
  • Accepted : 2024.06.04
  • Published : 2024.05.30
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Abstract

Introduction: We describe the effects of Sosiho-tang decoction and insulin combination therapy, as well as the effect of integrated traditional Korean medicine therapy, using continuous glucose monitoring (CGM) in a diabetic patient complaining of a range of diabetic symptoms. Case report: A 24-year-old female presented with symptoms of diabetes, including weight loss, thirst, and polyuria, and was diagnosed with type 2 diabetes through blood tests, endocrine tests, and autoantibody tests. During hospitalization, the patient received insulin therapy and Sosiho-tang decoction concurrently, achieving normal blood glucose levels. After discharge, adhering to the Sosiho-tang decoction and CGM enabled the insulin dosage to be gradually reduced while maintaining normal blood glucose levels. Conclusion: Combination therapy with insulin and Sosiho-tang rapidly reduced hyperglycemia in the short term. CGM post-discharge allowed for observation of the patient's blood glucose levels. Ultimately, Sosiho-tang medication lowered blood glucose levels, reduced insulin requirements, and facilitated a reduction in the insulin dosage.

Keywords

Acknowledgement

본 연구는 보건복지부의 재원으로 한국보건산업진흥원의 보건의료기술 연구개발사업 지원에 의하여 이루어진 것임(HF20C0022).

References

  1. American Diabetes Association Professional Practice Committee. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes-2024. Diabetes Care 2024;47(Suppl 1):S158-S178. 
  2. 건강보험심사평가원. 건강보험심사평가원 통계. 강원: 건강보험심사평가원; 2022. 
  3. Korean Diabetes Association. Clinical Practice Guidelines for Diabetes 2023. Seoul: Korean Diabetes Association. 
  4. 대한한방내과학회. 2형 당뇨병 한의표준임상진료지침. 경산: 한국한의약진흥원 한의약혁신기술개발사업단; 2023. 
  5. Korean Diabetes Association. Diabetes Fact Sheet in Korea 2022. Seoul: Korean Diabetes Association; 2020. 
  6. 건강보험심사평가원. 2020. https://www.hira.or.kr/main.do. 
  7. Wang J, Wang L, Lou GH, Zeng HR, Hu J, Huang QW, et al. Coptidis Rhizoma: a comprehensive review of its traditional uses, botany, phytochemistry, pharmacology and toxicology. Pharm Biol 2019;57(1):193-225. 
  8. Meng FC, Wu ZF, Yin ZQ, Lin LG, Wang R, Zhang QW. Coptidis rhizoma and its main bioactive components: recent advances in chemical investigation, quality evaluation and pharmacological activity. Chin Med 2018;13:13. 
  9. Meng Q, Qi X, Fu Y, Chen Q, Cheng P, Yu X, et al. Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes. J Ethnopharmacol 2020;248:112326. 
  10. Yang JH, Han JS. Effect of Mulberry Leak Extract Supplement on Blood Glcose, Glycated Hemohlobin and Serum Lipids in Type 2 diabetes Patients. J Korean Soc ood Sci Nutr 2006;35(5):549-56. 
  11. Sham TT, Yuen CY, Chan CO, Mok KW, Chan SW, Ng YF. A Review of the Phytochemistry and Pharmacological Activities. Evidence-Based Complementary and Alternative Medicine 2013;2013:636194. 
  12. Kim JE, Hwang IS, Choi SI, Lee HR, Lee YJ, Goo JS, et al. Aqueous extract of Liriope platyphylla, a traditional Chinese medicine, significantly inhibits abdominal fat accumulation and improves glucose regulation in OLETF type II diabetes model rats. Lab Anim Res 2012;28(3):181-91. 
  13. Matsuda HS, Nagatomo AF, Hatakeyama MS, Manse YA, Yoshikawa MY, Morikawa TH. Suppressive effects of Bombycis Feces (bombyx feces) and Bombyx Batryticatus (stiff silkworm) extracts on blood glucose level elevation in disaccharides-loaded rats. Traditional & Kampo Medicine 2023;10(2):132-41. 
  14. Leelarathna L, Evans ML, Neupane S, Rayman G, Lumley S, Cranston I, et al. Intermittently Scanned Continuous Glucose Monitoring for Type 1 Diabetes. Engl J Med 2022;387(16):1477-87.