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A Rare Case of Clear Cell Carcinoma of the Tongue Base: A Case Report

혀 기저부에 발생한 투명세포암종 1예

  • Hong Jin Kim (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Korea University Ansan Hospital) ;
  • Ye Hwan Lee (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Korea University Ansan Hospital) ;
  • HwaEun Oh (Department of Pathology, College of Medicine, Korea University Ansan Hospital) ;
  • Kyung Ho Oh (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Korea University Ansan Hospital) ;
  • Soon Young Kwon (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Korea University Ansan Hospital)
  • 김홍진 (고려대학교 의과대학 안산병원 이비인후-두경부외과학교실) ;
  • ;
  • 오화은 (고려대학교 의과대학 안산병원 병리과학교실) ;
  • 오경호 (고려대학교 의과대학 안산병원 이비인후-두경부외과학교실) ;
  • 권순영 (고려대학교 의과대학 안산병원 이비인후-두경부외과학교실)
  • Received : 2023.09.27
  • Accepted : 2023.11.23
  • Published : 2024.05.30

Abstract

Clear cell carcinoma is a rare variant of salivary gland carcinoma, and its occurrence in the tongue base is even rarer. We present a case of a 55-year-old female patient with clear cell carcinoma of the tongue base. The patient initially presented with a 3-month history of palpable tongue mass, leading to her visit to the otolaryngology outpatient clinic. The patient underwent a complete resection of the tumor under general anesthesia. Postoperative follow-up imaging studies showed no evidence of recurrence. This case report highlights the diagnostic and management challenges associated with clear cell carcinoma of tongue base and demonstrates that a high index of suspicion is required to diagnose clear cell caricnoma, given its rarity and overlapping features with other clear cell neoplasms.

Keywords

References

  1. Kenichi W, Yuri O, Ken H, Takashi S. Clear cell carcinoma of the base of the tongue: A case report and review of the literature. Ann Otol Rhino Laryngol. 2015;124(1):55-61 
  2. Antonieta A , Brian L, Richard C. Hyalinizing clear cell carcinoma: Case series and comprehensive review of the literature. Cancer. 2009;115(1):75-83. 
  3. Eversole LR. Clinical Outline of Oral Pathology: Diagnosis and Treatment. 4th ed. Shelton, CT: People's Medical Publishing House-USA; 2011. 
  4. Nataraj P, Partheeban B, Nehla I. Hyalinizing Clear Cell Carcinoma: Base of Tongue. Indian J Otolaryngol Head Neck Surg. 2019; 71:239-242. 
  5. Seethala RR. An Update on grading of salivary gland carcinomas. Head Neck Pathol. 2009;3:69-77. 
  6. Fabio RP, Gordon AP, Oslei PA, Sow YC. Intra-oral minor salivary gland tumors: a clinicopathological study of 546 cases. Oral Oncol. 2007;43:463-470. 
  7. Thiagarajan S, Nair S, Nair D, et al. Clear cell tumors of the head and neck: a review. J Oral Maxillofac Pathol. 2015;19:69-76. 
  8. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO Classification of Head and Neck Tumours. 4th ed. Lyon, France: IARC Press; 2017. 
  9. Wenig BM. Clear cell neoplasms in salivary glands: Clearly a diagnostic challenge. Ann Diagn Pathol. 2016;20:73-75. 
  10. Samia A, Nawal H, Mohamed AE. Clear Cell Carcinoma of Minor Salivary Glands: The Nasopharynx, an Uncommon Site of Origin. Cureus. 2022;14:225033. 
  11. Garry LE. Clear cell neoplasms in salivary glands: Clearly a diagnostic challenge. Annals of Diagnostic Pathology. 1998;2:61-78.