Journal of the korean academy of Pediatric Dentistry (대한소아치과학회지)

Korean Academy of Pediatric Dentistry (대한소아치과학회)
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Enhancing the Physicochemical Properties of Sodium Iodide-based Root Canal Filling Material with Lanolin Incorporation

  • Hye Shin Park (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • Jongsoo Kim (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • Joonhaeng Lee (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • Jisun Shin (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • Mi Ran Han (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • Jongbin Kim (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • Yujin Kim (Department of Biomaterials Science, College of Dentistry, Dankook University) ;
  • Junghwan Lee (Department of Biomaterials Science, College of Dentistry, Dankook University)
  • Received : 2024.02.01
  • Accepted : 2024.03.08
  • Published : 2024.05.31
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Abstract

This study aimed to enhance the physicochemical properties of sodium iodide-based root filling materials, particularly solubility. In earlier developmental stages, the iodoform-containing paste exhibited high antibacterial efficacy but failed to meet only the solubility requirement among the ISO 6876 criteria. Therefore, this study focused on enhancing the physicochemical properties of the paste under development, particularly centering on reducing its solubility. Four experimental groups were established, including three control group. The previously developed D30 paste was named the Oil 33 group, and the control group was named the Vitapex® group. The Oil 50 group, in which the oil content was increased, and the Oil 45L group, in which lanolin was incorporated. The physical properties (solubility, pH, flowability, and film thickness) of the four pastes were evaluated according to the ISO 6876 standards. No significant differences were observed between the Oil 45L and Vitapex® groups in any of the physical property evaluations. While the Oil 33 and Oil 50 groups met the ISO 6876 standards for flowability and film thickness, the Oil 45L group met all the physical properties. However, reducing the overall oil content may be necessary to enhance the antimicrobial properties. The result of the physicochemical experiments showed that the Oil 45L group with the newly formulated composition and incorporated lanolin exhibited low solubility meeting the ISO 6876 standard of ≤ 3%. We were able to develop a paste with more stable solubility than previous iodide-based root-filling materials. Therefore, the oil content must be further adjusted to improve its antimicrobial properties. If other physical properties also meet the ISO 6876 standards and demonstrate excellent results in cytotoxicity tests, this root filling material could potentially replace existing options.

Keywords

Acknowledgement

This research was funded by the Department of Dentistry (Pediatric Dentistry), the Research-Focused Department Promotion Project as part of the University Innovation Support Program for Dankook University in 2021 (2020R1G1A1009155), and the Basic Science Research Program funded by the Ministry of Education (NRF-2022R1I1A1A01069606).

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