DOI QR코드

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Pulp stones: any relevance with the levels of serum calcium, parathyroid hormone, vitamin D and uric acid

  • Ceyda Gurhan (Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Mugla Sitki Kocman University ) ;
  • Ercan Saruhan (Department of Medical Biochemistry, Faculty of Medicine, Mugla Sitki Kocman University)
  • 투고 : 2023.11.24
  • 심사 : 2024.01.08
  • 발행 : 2024.05.31

초록

Objectives: This study evaluated the effect of serum calcium, parathyroid hormone (PTH), vitamin D, and uric acid levels on pulp stone formation. Materials and Methods: Patients who were admitted to the Muğla Sıtkı Koçman University, Faculty of Dentistry, Department of Oral and Maxillofacial Radiology for dental complaints were registered. Among these patients, individuals who had routine biochemical tests at the same period in the Outpatient Clinics of Muğla Sıtkı Koçman University Training and Research Hospital were included in the study. The patients with at least 1 pulp stone on panoramic radiographs recorded as the "pulp stone group" while patients without any pulp stones were the "control group". Demographic data and serum levels of calcium, PTH, vitamin D, and uric acid were retrospectively evaluated in both groups. Student t-test or Mann-Whitney U test was used to evaluate the differences between the groups. Results: Among 151 patients, dental pulp stone was detected in 53.6% of patients, and 82.7% of these patients were female. Female sex and pulp stone formation were significantly associated (p = 0.001). The mean age of the pulp stone group was 43.9, while it was 39.9 in the control group, without any significant correlation between age and pulp stone (p > 0.05). Similarly, there were no significant differences in serum levels of PTH, vitamin D, uric acid and calcium between groups (p > 0.05). Conclusions: According to the present study, the effect of dental factors rather than systemic factors should be considered primarily in pulp stone formation.

키워드

과제정보

The authors would like to thank Professor Pelin Guneri for her language support and valuable advice.

참고문헌

  1. Jain P, Patni P, Hiremath H, Jain N. Successful removal of a 16 mm long pulp stone using ultrasonic tips from maxillary left first molar and its endodontic management. J Conserv Dent 2014;17:92-95. https://doi.org/10.4103/0972-0707.124170
  2. Kannan S, Kannepady SK, Muthu K, Jeevan MB, Thapasum A. Radiographic assessment of the prevalence of pulp stones in Malaysians. J Endod 2015;41:333-337. https://doi.org/10.1016/j.joen.2014.10.015
  3. Ashutosh H, Pragya H, Divya KJ, Ramniwas K, Sharad P, Mansoor S. Correlation between pulp stones and serum calcium levels: a preliminary study. Int J Health Clin Res 2021;4:145-147. 
  4. Patil S, Sinha N. Pulp stone, haemodialysis, end-stage renal disease, carotid atherosclerosis. J Clin Diagn Res 2013;7:1228-1231. https://doi.org/10.7860/JCDR/2013/5087.3042
  5. Gunen Yilmaz S, Yilmaz F, Bayrakdar IS, Harorli A. The relationship between carotid artery calcification and pulp stone among hemodialysis patients: a retrospective study. Saudi J Kidney Dis Transpl 2019;30:755-763. https://doi.org/10.4103/1319-2442.265449
  6. Goga R, Chandler NP, Oginni AO. Pulp stones: a review. Int Endod J 2008;41:457-468. https://doi.org/10.1111/j.1365-2591.2008.01374.x
  7. Ertas ET, Veli I, Akin M, Ertas H, Atici MY. Dental pulp stone formation during orthodontic treatment: a retrospective clinical follow-up study. Niger J Clin Pract 2017;20:37-42. https://doi.org/10.4103/1119-3077.164357
  8. S N, Chandran A, B S, S G, A M, Muddebihal F, et al. Pulp stones: diagnostic significance in early diagnosis and radiographic correlation with ischemic heart diseases. Indian J Radiol Imaging 2021;31:277-283. https://doi.org/10.1055/s-0041-1731829
  9. Patil SR. Prevalence of and relationship between pulp and renal stones: a radiographic study. J Oral Biol Craniofac Res 2015;5:189-192. https://doi.org/10.1016/j.jobcr.2015.06.010
  10. Gabardo MCL, Wambier LM, Rocha JS, Kuchler EC, de Lara RM, Leonardi DP, et al. Association between pulp stones and kidney stones: a systematic review and meta-analysis. J Endod 2019;45:1099-1105.e2. https://doi.org/10.1016/j.joen.2019.06.006
  11. Gabardo MCL, Kublitski PMO, Sette IR, Lauschner T, Juglair MM, Baratto-Filho F, et al. Sialometric and sialochemical analysis in individuals with pulp stones. Front Cell Dev Biol 2020;8:403.
  12. Turkal M, Tan E, Uzgur R, Hamidi M, Colak H, Uzgur Z. Incidence and distribution of pulp stones found in radiographic dental examination of adult Turkish dental patients. Ann Med Health Sci Res 2013;3:572-576. https://doi.org/10.4103/2141-9248.122115
  13. Ivanauskaite D, Kubiliute D, Janaviciene D, Brukiene V. Prevalence of pulp stones in molars based on bitewing and periapical radiographs. Stomatologija 2021;23:9-15.
  14. Gulsahi A, Cebeci AI, Ozden S. A radiographic assessment of the prevalence of pulp stones in a group of Turkish dental patients. Int Endod J 2009;42:735-739. https://doi.org/10.1111/j.1365-2591.2009.01580.x
  15. Sisman Y, Aktan AM, Tarim-Ertas E, Ciftci ME, Sekerci AE. The prevalence of pulp stones in a Turkish population. A radiographic survey. Med Oral Patol Oral Cir Bucal 2012;17:e212-e217. https://doi.org/10.4317/medoral.17400
  16. Ravanshad S, Khayat S, Freidonpour N. The prevalence of pulp stones in adult patients of Shiraz dental school, a radiographic assessment. J Dent (Shiraz) 2015;16:356-361.
  17. Jannati R, Afshari M, Moosazadeh M, Allahgholipour SZ, Eidy M, Hajihoseini M. Prevalence of pulp stones: a systematic review and meta-analysis. J Evid Based Med 2019;12:133-139. https://doi.org/10.1111/jebm.12331
  18. Ranjitkar S, Taylor JA, Townsend GC. A radiographic assessment of the prevalence of pulp stones in Australians. Aust Dent J 2002;47:36-40. https://doi.org/10.1111/j.1834-7819.2002.tb00301.x
  19. Ravichandran S, Vadivel JK. Prevalence of pulp stones in IOPA radiographs. J Adv Pharm Technol Res 2022;13:S63-S66. https://doi.org/10.4103/japtr.japtr_126_22
  20. Hsieh CY, Wu YC, Su CC, Chung MP, Huang RY, Ting PY, et al. The prevalence and distribution of radiopaque, calcified pulp stones: a cone-beam computed tomography study in a northern Taiwanese population. J Dent Sci 2018;13:138-144. https://doi.org/10.1016/j.jds.2017.06.005
  21. Babu SJ, Swarnalatha C, Rao AP, Kumar BB, Tilak BP, Naidu RB, et al. Pulp stones as risk predictors for coronary artery disease. Int J Prev Med 2020;11:7.
  22. Aleksova P, Serafimoski V, Popovska M, Ristovski M. Pulp stones can help in detection of calculus in the kidneys and/or in the bile--fact or fiction? Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2013;34:159-167.
  23. Tarim Ertas E, Inci M, Demirtas A, Ertas H, Yengil E, Sisman Y, et al. A radiographic correlation between renal and pulp stones. West Indian Med J 2014;63:620-625.
  24. Galav A, Vyas T, Kaur M, Chauhan M, Satija N, et al.Association of pulp stones & renal stones- a clinical study. Int J Res Health Allied Sci 2018;4:82-84. 
  25. Kumar T, Puri G, Aravinda K, Laller S, Jatti D, Gupta R. Correlation between prevalence of pulp stones and renal stones in Panchkula region of India. SRM J Res Dent Sci 2015;6:150-154. https://doi.org/10.4103/0976-433X.162156
  26. Movahhedian N, Haghnegahdar A, Owji F. How the prevalence of pulp stone in a population predicts the risk for kidney stone. Iran Endod J 2018;13:246-250.
  27. Moudi E, Kazemi A, Madani Z, Haghanifar S, Moudi E. A radiographic correlation between the presence of pulp stones and kidney stones. Casp J Appl Sci Res 2015;4:1-7. 
  28. Jawahar G, Rao GN, Vennila AA, Fathima SD, Lawanya MKK, Doss DM, et al. Clinicopathological correlation of pulp stones and its association with hypertension and hyperlipidemia: an hospital-based prevalence study. J Pharm Bioallied Sci 2021;13:S1268-S1274. https://doi.org/10.4103/jpbs.jpbs_475_21
  29. Yeluri G, Kumar CA, Raghav N. Correlation of dental pulp stones, carotid artery and renal calcifications using digital panoramic radiography and ultrasonography. Contemp Clin Dent 2015;6:S147-S151. https://doi.org/10.4103/0976-237X.166837
  30. Kansu O, Ozbek M, Avcu N, Aslan U, Kansu H, Genctoy G. Can dental pulp calcification serve as a diagnostic marker for carotid artery calcification in patients with renal diseases? Dentomaxillofac Radiol 2009;38:542-545. https://doi.org/10.1259/dmfr/13231798
  31. Auron A, Alon US. Hypercalcemia: a consultant's approach. Pediatr Nephrol 2018;33:1475-1488. https://doi.org/10.1007/s00467-017-3788-z
  32. Botelho J, Machado V, Proenca L, Delgado AS, Mendes JJ. Vitamin D deficiency and oral health: a comprehensive review. Nutrients 2020;12:1471. 
  33. Uwitonze AM, Rahman S, Ojeh N, Grant WB, Kaur H, Haq A, et al. Oral manifestations of magnesium and vitamin D inadequacy. J Steroid Biochem Mol Biol 2020;200:105636.
  34. Giunta JL. Dental changes in hypervitaminosis D. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;85:410-413. https://doi.org/10.1016/S1079-2104(98)90066-X