Pediatric Infection and Vaccine

The Korean Society of Pediatric Infectious Diseases (대한소아감염학회)
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Febrile Seizure Associated With COVID-19 in a Child: Case Report and Literature Review

소아 코로나바이러스감염증-19에서 발생한 열성 경련

  • Yu Ri Jo (Department of Pediatrics, Inha University School of Medicine) ;
  • Nayoung Jung (Department of Pediatrics, Inha University School of Medicine) ;
  • Min Kyoung Kim (Department of Pediatrics, Seonam Hospital) ;
  • Young Se Kwon (Department of Pediatrics, Inha University School of Medicine) ;
  • Dong Hyun Kim (Department of Pediatrics, Inha University School of Medicine)
  • 조유리 (인하대학교 의과대학 소아과학교실) ;
  • 정나영 (인하대학교 의과대학 소아과학교실) ;
  • 김민경 (서울특별시 서남병원 소아청소년과) ;
  • 권영세 (인하대학교 의과대학 소아과학교실) ;
  • 김동현 (인하대학교 의과대학 소아과학교실)
  • Received : 2021.09.24
  • Accepted : 2024.01.14
  • Published : 2024.04.25
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Abstract

There have been several case reports of neurological manifestations in pediatrics as severe acute respiratory syndrome coronavirus-2 infection in children is being increased. We report a case of a 4-year-old boy who presented febrile seizure during follow-up in a negative pressure isolation room after confirmed coronavirus disease 2019, which has not yet been reported in Korea. He has no symptoms other than fever. The seizure was controlled after one dose of intravenous lorazepam, and there was no respiratory support during the hospitalization. He was discharged 12 days later without neurological sequelae.

기저 질환 없이 평소 건강하던4세 남아에서 COVID-19와 연관된 열성 경련이 발생하였다. SARS-CoV-2 양성으로 확인되어 음압격리병동에 입원한 당일 발열과 함께 25분간 전신 간대성 발작이 있었고 산소흡입, 항경련제 투여 후 소실되었다. 말초혈액, 혈액화학, 전해질, 혈액기체분석, 급성기반응물질, 면역혈청, 특수화학 검사 결과들은 참고치 내에 있었으나, 소변검사에서 케톤이 검출되었다. 가슴X선 영상검사에서 활동성 폐병변이 관찰되지 않았고, 뇌파 검사에서 이상 소견 없었다. 뇌 자기공명영상 검사에서 뇌실질 내외의 병변은 없었다. 발작은 재발하지 않았고 입원 12병일째 퇴원하였으며 신경학적 후유증은 없었다.

Keywords

Acknowledgement

The Inha University Research Grant supported this study.

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