Animal Bioscience

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
권호 표지
DOI QR코드

DOI QR Code

Effect of Andrographis paniculata supplementation during the transition period on colostrum yield, immunoglobulin G, and postpartum complications in multiparous sows during tropical summer

  • Padet Tummaruk (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Kankawee Petchsangharn (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Kanyakon Shayutapong (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Thanwarat Wisetsiri (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Patcharin Krimtum (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Sidthipong Kaewkaen (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Preechaphon Taechamaeteekul (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Natchanon Dumniem (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Junpen Suwimonteerabutr (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Fabio De Rensis (Department of Veterinary Medical Science, University of Parma)
  • Received : 2023.05.18
  • Accepted : 2023.11.16
  • Published : 2024.05.01
Download PDF
⟨ Previous Next ⟩

Abstract

Objective: This study evaluated the effect of Andrographis paniculata (A. paniculata) supplementation in sow diets before and after farrowing on the sow and piglets' performances during early postpartum period and on sows' backfat and longissimus muscle losses during lactation. Methods: Seventy Landrace×Yorkshire sows and their offspring (1,186 piglets) were distributed into three groups: control (n = 31), treatment-250 (n = 18), and treatment-1000 (n = 21). From 110.2±0.7 days of gestation until farrowing (5.8 days) and throughout the lactation period (25.2 days), sows in the control group were given the conventional lactation diet, while sows in the treatment-250 and treatment-1000 groups received supplements of 250 ppm and 1,000 ppm of A. paniculata, respectively. Results: In sows with parity 3-5, piglets from the treatment-1000 group had higher colostrum intake than the control and treatment-250 groups (p<0.05), but not in sows with parity 6-9. Colostrum immunoglobulin G (IgG) increased in treated sows versus controls for parity 6-9 (p<0.05), but was consistent for parity 3-5. Piglet performance until day 3 postnatal was similar across groups (p>0.05). Treatment-250 sows had higher feed intake post-farrowing than treatment-1000 sows (p<0.05). Longissimus loss was less in both treatment groups than control (p<0.05), but backfat loss was similar across groups (p>0.05). Post-partum complications were consistent across groups (p>0.05). Farrowing duration and piglet birth intervals in sows with parity 6-9 were prolonged in the treatment-1000 group. Conclusion: Supplementing with 1,000 ppm A. paniculata for 5.8 days pre-farrowing and 25.2 days post-farrowing enhanced sow colostrum IgG and piglet colostrum intake, while also reducing longissimus loss in sows. However, for sows of parity 6-9, this supplementation led to prolonged farrowing, increased intervals between piglet births, increased stillbirth, and reduced piglet birth weight. These effects should be considered when using A. paniculata supplementation.

Keywords

Acknowledgement

The authors wish to express their appreciation to Mr. Thawatchai Kositkittiwanit and the farm personnel for their invaluable aid in animal management.

References

  1. Tokach MD, Menegat MB, Gourley KM, Goodband RD. Review: nutrient requirements of the modern high-producing lactating sow, with an emphasis on amino acid requirements. Animal 2019;13:2967-77. https://doi.org/10.1017/S1751731119001253
  2. Peltoniemi O, Oliviero C, Yun J, Grahofer A, Bjorkman S. Management practices to optimize the parturition process in the hyperprolific sow. J Anim Sci 2020;98:S96-S106. https://doi.org/10.1093/jas/skaa140
  3. Tummaruk P. Post-parturient disorders and backfat loss in tropical sows in relation to backfat thickness before farrowing and postpartum intravenous supportive treatment. Asian-Australas J Anim Sci 2013;26:171-7. https://doi.org/10.5713/ajas.2012.12478
  4. Oliviero C. Management to improve neonate piglet survival. In: Rodriquez-Martinez H, Soede NM, Flowers WL, editors. Control of pig reproduction IX: Proceedings of the ninth international conference on pig reproduction 2013; 2013 June: Olsztyn, Poland. Leicestershire, UK: Context Products Ltd; 2013. pp. 203-10. https://doi.org/10.1530/biosciprocs.19.0021
  5. Decaluwe R, Maes D, Wuyts B, Cools A, Piepers S, Janssens GPJ. Piglets' colostrum intake associates with daily weight gain and survival until weaning. Livest Sci 2014;162:185-92. https://doi.org/10.1016/j.livsci.2014.01.024
  6. Nuntapaitoon M, Suwimonteerabutr J, Am-in N, et al. Impact of parity and housing conditions on concentration of immunoglobulin G in sow colostrum. Trop Anim Health Prod 2019;51:1239-46. https://doi.org/10.1007/s11250-019-01816-2
  7. Le Dividich J, Rooke JA, Herpin P. Nutrition and immunological importance of colostrum for the new-born pig. J Agric Sci 2005;143:469-85. https://doi.org/10.1017/S0021859605005642
  8. Quesnel H, Farmer C, Devillers N. Colostrum intake: influence on piglet performance and factors of variation. Livest Sci 2012;146:105-14. https://doi.org/10.1016/j.livsci.2012.03.010
  9. Declerck I, Dewulf J, Sarrazin S, Maes D. Long-term effects of colostrum intake in piglet mortality and performance. J Anim Sci 2016;94:1633-43. https://doi.org/10.2527/jas.20159564
  10. Pandey G, Rao CH. Andrographolide: Its pharmacology, natural bioavailability and current approaches to increase its content in Andrographis paniculata. Int J Complement Altern Med 2018;11:355-60. https://doi.org/10.15406/ijcam.2018.11.00425
  11. Dai Y, Chen SR, Chai L, Zhao J, Wang Y, Wang Y. Overview of pharmacological activities of Andrographis paniculata and its major compound andrographolide. Crit Rev Food Sci Nutr 2019;59:S17-S29. https://doi.org/10.1080/10408398.2018.1501657
  12. Jarukamjorn K, Nemoto N. Pharmacological aspects of Andrographis paniculata on health and its major diterpenoid constituent andrographolide. J Health Sci 2008;54:370-81. https://doi.org/10.1248/jhs.54.370
  13. Mehta S, Sharma AK, Singh RK. Pharmacological activities and molecular mechanisms of pure and crude extract of Andrographis paniculata: an update. Phytomed Plus 2021;1:100085. https://doi.org/10.1016/j.phyplu.2021.100085
  14. Maurya VK, Kumar S, Prasad AK, Bhatt MLB, Saxena SK. Structure-based drug designing for potential antiviral activity of selected natural products from Ayurveda against SARSCoV-2 spike glycoprotein and its cellular receptor. Virusdisease 2020;31:179-93. https://doi.org/10.1007/s13337-020-00598-8
  15. Enmozhi SK, Raja K, Sebastine I, Joseph J. Andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach. J Biomol Struct Dyn 2021;39:3092-8. https://doi.org/10.1080/07391102.2020.1760136
  16. Tummaruk P, Limtrajitt V, Kunavongkrit A. The supplementation of Andrograpis paniculata in the feed of lactating sows reduce pre-weaning mortality and increase number of piglets at weaning. In: Proceedings of the 4th Asian Society of Veterinary Pathologists (ASVP) Conference and Annual Meeting of the Thai Association of Veterinary Laboratory Diagnosticians (TAVLD) -1; 2009 Nov 19-20: Bangkok, Thailand.
  17. Tummaruk P, Limtrajitt V. The influence of Andrographis paniculata compound on average daily feed intake of lactating sows and the litter weight gain of piglets: a field trial. In: Proceedings of the 48th Kasetsart Annual Conference; 2010 Feb 3-5: Kasetsart, Thailand.
  18. Theil PK, Lauridsen C, Quesnel H. Neonatal piglet survival: impact of sow nutrition around parturition on fetal glycogen deposition and production and composition of colostrum and transient milk. Animal 2014;8:1021-30. https://doi.org/10.1017/S1751731114000950
  19. Hasan SMK, Junnikkala S, Valros A, Peltoniemi O, Oliviero C. Validation of Brix refractometer to estimate colostrum immunoglobulin G content and composition in the sow. Animal 2016;10:1728-33. https://doi.org/10.1017/S1751731116000896
  20. Committee on Nutrient Requirements of Swine, National Research Council. Nutrient requirements of swine. 11th ed. Washington, DC, USA: National Academy Press; 2012.
  21. Khamtawee I. Singdamrong K, Tatanan P, et al. Cinnamon oil supplementation of the lactation diet improves feed intake of multiparous sows and reduces pre-weaning piglet mortality in a tropical environment. Livest Sci 2021;251:104657. https://doi.org/10.1016/j.livsci.2021.104657
  22. Oliviero C, Heinonen M, Valros A, Peltoniemi O. Environmental and sow-related factors affecting the duration of farrowing. Anim Reprod Sci 2010;119:85-91. https://doi.org/10.1016/j.anireprosci.2009.12.009
  23. Tummaruk P, Pearodwong P. Postparturient disorders and backfat loss in tropical sows associated with parity, farrowing duration and type of antibiotic. Trop Anim Health Prod 2015;47:1457-64. https://doi.org/10.1007/s11250-015-0883-7
  24. Han T, Bjorkman S, Soede NM, Oliviero C, Peltoniemi OAT. IGF-1 concentration patterns and their relationship with follicle development after weaning in young sows fed different pre-mating diets. Animal 2020;14:1493-501. https://doi.org/10.1017/S1751731120000063
  25. Boonraungrod N, Sutthiya N, Kumwan P, et al. Control of parturition in swine using PGF2α in combination with carbetocin. Livest Sci 2018;214:1-8. https://doi.org/10.1016/j.livsci.2018.05.012
  26. Jiarpinitnun P, Loyawatananan S, Sangratkanjanasin P, et al. Administration of carbetocin after the first piglet was born reduced farrowing duration but compromised colostrum intake in newborn piglets. Theriogenology 2019;128:23-30. https://doi.org/10.1016/j.theriogenology.2019.01.021
  27. Tummaruk P, Tantasuparuk W, Techakumphu M, Kunavongkrit A. Seasonal influences on the litter size at birth of pigs are more pronounced in the gilt than sow litters. J Agric Sci 2010;148:421-32. https://doi.org/10.1017/S0021859610000110
  28. Muns R, Nuntapaitoon M, Tummaruk P. Non-infectious causes of pre-weaning mortality in piglets. Livest Sci 2016; 184:46-57. https://doi.org/10.1016/j.livsci.2015.11.025
  29. Nuntapaitoon M, Tummaruk P. Piglet preweaning mortality in a commercial swine herd in Thailand. Trop Anim Health Prod 2015;47:1539-46. https://doi.org/10.1007/s11250-0150895-3
  30. Nuntapaitoon M, Tummaruk P. Factors influencing piglet pre-weaning mortality in 47 commercial swine herds in Thailand. Trop Anim Health Prod 2018;50:129-35. https://doi.org/10.1007/s11250-017-1412-7
  31. Salmon H, Berri M, Gerdts V, Meurens F. Humoral and cellular factors of maternal immunity in swine. Dev Comp Immunol 2009;33:384-93. https://doi.org/10.1016/j.dci.2008.07.007
  32. Vallet JL, Miles JR, Rempel LA. A simple novel measure of passive transfer of maternal immunoglobulin is predictive of preweaning mortality in piglets. Vet J 2013;195:91-7. https://doi.org/10.1016/j.tvjl.2012.06.009
  33. Foisnet A, Farmer C, David C, Quesnel H. Relationship between colostrum production by primiparous sows and sow physiology around parturition. J Anim Sci 2010;88:1672-83. https://doi.org/10.2527/jas.2009-2562
  34. Ferrari CV, Sbardella PE, Bernardi ML, et al. Effect of birth weight and colostrum intake on mortality and performance of piglets after cross-fostering in sows of different parities. Prev Vet Med 2014;114:259-66. https://doi.org/10.1016/j.prevetmed.2014.02.013
  35. Krogh U, Bruun TS, Amdi C, Flummer C, Poulsen J, Theil PK. Colostrum production in sows fed different sources of fiber and fat during late gestation. Can J Anim Sci 2015;95:211-23. https://doi.org/10.4141/cjas-2014-060
  36. Devillers N, Le Dividich J, Prunier A. Influence of colostrum intake on piglet survival and immunity. Animal 2011;5:1605-12. https://doi.org/10.1017/S175173111100067X
  37. Juthamanee P, Tummaruk P. Factors associated with colostrum consumption in neonatal piglets. Livest Sci 2021;251:104630. https://doi.org/10.1016/j.livsci.2021.104630
  38. Nuntapaitoon M, Juthamanee P, Theil PK, Tummaruk P. Impact of sow parity on yield and composition of colostrum and milk in Danish Landrace × Yorkshire crossbred sows. Prev Vet Med 2020;181:105085. https://doi.org/10.1016/j.prevetmed.2020.105085
  39. Maes DGD, Janssens GPJ, Delputte P, Lammertyn A, de Kruif A. Back fat measurements in sows from three commercial pig herds: relationship with reproductive efficiency and correlation with visual body condition scores. Livest Prod Sci 2004;91:57-67. https://doi.org/10.1016/j.livprodsci.2004.06.015
  40. Costermans NGJ, Teerds KJ, Middelkoop A, et al. Consequences of negative energy balance on follicular development and oocyte quality in primiparous sows. Biol Reprod 2020;102:388-98. https://doi.org/10.1093/biolre/ioz175