The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Effect of Herbal Medicine on Transient Synovitis of Hip in Children: A Systemic Review and Meta-analysis

소아 일과성 고관절 활액막염에 대한 한약의 효과: 체계적 문헌 고찰 및 메타분석

  • Hong Ye Na (Department of Pediatrics, College of Korean Medicine, Dongeui University) ;
  • Lee Young Hun (Department of Rehabilitation, College of Korean Medicine, Dongeui University) ;
  • Yu Sun Ae (Department of Pediatrics, College of Korean Medicine, Dongeui University)
  • 홍예나 (동의대학교 한의과대학 한방소아과학교실) ;
  • 이영훈 (동의대학교 한의과대학 한방재활의학과교실) ;
  • 유선애 (동의대학교 한의과대학 한방소아과학교실)
  • Received : 2023.10.31
  • Accepted : 2023.11.24
  • Published : 2023.11.30
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Abstract

Objective This study aimed to evaluate the effect of herbal medicines on transient hip synovitis (TSH) in children. Methods We searched 10 Korean, English, Japanese, and Chinese databases for studies published up to September 19, 2023. Randomized controlled trials (RCTs) evaluating the effect of herbal medicines on TSH levels in children were included. The Cochrane risk of bias was used to evaluate the quality of the studies. A meta-analysis was conducted according to outcome measurements, such as total effective rate (TER), visual analog score (VAS), time to pain relief, and hip joint mobility disorder disappearance time, using the Review Manager website. Results Eleven RCTs were included in this study. TER in the treatment group was significantly higher than in the control group. The duration of pain relief was significantly shorter in the treatment group than in the control group. The VAS score of the treatment group was significantly lower than that of the control group, although the statistical heterogeneity was substantial. The hip joint mobility disorder disappeared in the treatment group treated with external therapy, which was significantly shorter than in the control group. Regarding safety, two of the 11 studies reported that there were no adverse events. Conclusions Herbal medicines are effective in the treatment of TSH in children. However, the safety of herbal medicines should be carefully considered due to the lack of data.

Keywords

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