Acknowledgement
This research was supported by grants from the Kasetsart Veterinary Development Funds, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
References
- Levack AE, Turajane K, Driscoll DA, Yang X, Miller AO, Bostrom MP, et al. Identifying alternative antibiotics that elute from calcium sulfate beads for treatment of orthopedic infections. J Orthop Res. 2022;40(5):1143-1153. https://doi.org/10.1002/jor.25135
- Lacqua A, Helmer P. Treatment of septic tenosynovitis and osteoarthritis in an American White Pekin (Anas platyrhynchos domesticus) with repeated intravenous regional limb perfusion and antibiotic-impregnated calcium sulfate beads. J Avian Med Surg. 2023;36(4):414-420. https://doi.org/10.1647/21-00056
- Peterson LC, Kim SE, Lewis DD, Johnson MD, Ferrigno CRA. Calcium sulfate antibiotic-impregnated bead implantation for deep surgical site infection associated with orthopedic surgery in small animals. Vet Surg. 2021;50(4):748-757. https://doi.org/10.1111/vsu.13570
- Wininger DA, Fass RJ. Antibiotic-impregnated cement and beads for orthopedic infections. Antimicrob Agents Chemother. 1996;40(12):2675-2679. https://doi.org/10.1128/AAC.40.12.2675
- Ricci JL, Weiner MJ, Mamidwar S, Alexander H. 14. Calcium sulfate. In: Kokubo T, editor. Bioceramics and Their Clinical Applications. Cambridge, England: Woodhead Publishing; 2008, 302-325.
- Thomas MV, Puleo DA. Calcium sulfate: properties and clinical applications. J Biomed Mater Res B Appl Biomater. 2009;88(2):597-610. https://doi.org/10.1002/jbm.b.31269
- Beuerlein MJ, McKee MD. Calcium sulfates: what is the evidence? J Orthop Trauma. 2010;24 Suppl 1:S46-S51. https://doi.org/10.1097/BOT.0b013e3181cec48e
- Merkatoris P, Schleining J, Krull A, Borts D, Fajt V. In vitro elution of penicillin, ampicillin, tetracycline, tulathromycin, and florfenicol from plaster of Paris beads. Front Vet Sci. 2020;7:585423.
- Atilla A, Boothe HW, Tollett M, Duran S, Diaz DC, Sofge J, et al. In vitro elution of amikacin and vancomycin from impregnated plaster of Paris beads. Vet Surg. 2010;39(6):715-721. https://doi.org/10.1111/j.1532-950X.2009.00632.x
- Parker AC, Smith JK, Courtney HS, Haggard WO. Evaluation of two sources of calcium sulfate for a local drug delivery system: a pilot study. Clin Orthop Relat Res. 2011;469(11):3008-3015. https://doi.org/10.1007/s11999-011-1911-1
- Webb ND, McCanless JD, Courtney HS, Bumgardner JD, Haggard WO. Daptomycin eluted from calcium sulfate appears effective against Staphylococcus. Clin Orthop Relat Res. 2008;466(6):1383-1387. https://doi.org/10.1007/s11999-008-0245-0
- Thitiyanaporn C, Thengchaisri N, Udomkusonsri P. Effect of porosity of calcium sulfate beads on ceftazidime elution and in vitro osteogenic properties. Agr Nat Resour. 2012;46(5):703-714.
- Minarikova A, Hauptman K, Knotek Z, Jekl V. Microbial flora of odontogenic abscesses in pet guinea pigs. Vet Rec. 2016;179(13):331.
- Muir P, Johnson KA. Anaerobic bacteria isolated from osteomyelitis in dogs and cats. Vet Surg. 1992;21(6):463-466. https://doi.org/10.1111/j.1532-950X.1992.tb00082.x
- Siqueira EG, Rahal SC, Ribeiro MG, Paes AC, Listoni FP, Vassalo FG. Exogenous bacterial osteomyelitis in 52 dogs: a retrospective study of etiology and in vitro antimicrobial susceptibility profile (2000-2013). Vet Q. 2014;34(4):201-204. https://doi.org/10.1080/01652176.2014.974000
- Brookins MD, Rajeev S, Thornhill TD, Kreinheder K, Miller DL. Mandibular and maxillary osteomyelitis and myositis in a captive herd of red kangaroos (Macropus rufus). J Vet Diagn Invest. 2008;20(6):846-849. https://doi.org/10.1177/104063870802000627
- Schnepf A, Kramer S, Wagels R, Volk HA, Kreienbrock L. Evaluation of antimicrobial usage in dogs and cats at a Veterinary Teaching Hospital in Germany in 2017 and 2018. Front Vet Sci. 2021;8:689018.
- Ramos JR, Howard RD, Pleasant RS, Moll HD, Blodgett DJ, Magnin G, et al. Elution of metronidazole and gentamicin from polymethylmethacrylate beads. Vet Surg. 2003;32(3):251-261. https://doi.org/10.1053/jvet.2003.50024
- Udomkusonsri P, Kaewmokul S, Arthitvong S, Phaochoosak N. Elution profiles of cefazolin from PMMA and calcium sulfate beads prepared from commercial cefazolin formulations. J Vet Med Sci. 2012;74(3):301-305. https://doi.org/10.1292/jvms.11-0095
- Ofokansi K, Uzor P. Stability studies and degradation kinetics of some commercially available metronidazole suspensions in Nigeria. J Pharm Allied Sci. 2011;8(3):1379-1386.
- Stephan B, Greife HA, Pridmore A, Silley P. Activity of pradofloxacin against Porphyromonas and Prevotella spp. implicated in periodontal disease in dogs: susceptibility test data from a European multicenter study. Antimicrob Agents Chemother. 2008;52(6):2149-2155. https://doi.org/10.1128/AAC.00019-08
- Tyrrell KL, Citron DM, Jenkins JR, Goldstein EJ. Periodontal bacteria in rabbit mandibular and maxillary abscesses. J Clin Microbiol. 2002;40(3):1044-1047. https://doi.org/10.1128/JCM.40.3.1044-1047.2002
- Knecht CS, Moley JP, McGrath MS, Granger JF, Stoodley P, Dusane DH. Antibiotic loaded calcium sulfate bead and pulse lavage eradicates biofilms on metal implant materials in vitro. J Orthop Res. 2018;36(9):2349-2354. https://doi.org/10.1002/jor.23903
- Butini ME, Cabric S, Trampuz A, Di Luca M. In vitro anti-biofilm activity of a biphasic gentamicin-loaded calcium sulfate/hydroxyapatite bone graft substitute. Colloids Surf B Biointerfaces. 2018;161:252-260. https://doi.org/10.1016/j.colsurfb.2017.10.050
- McKellar QA, Sanchez Bruni SF, Jones DG. Pharmacokinetic/pharmacodynamic relationships of antimicrobial drugs used in veterinary medicine. J Vet Pharmacol Ther. 2004;27(6):503-514. https://doi.org/10.1111/j.1365-2885.2004.00603.x
- Dusane DH, Brooks JR, Sindeldecker D, Peters CW, Li A, Farrar NR, et al. Complete killing of agar lawn biofilms by systematic spacing of antibiotic-loaded calcium sulfate beads. Materials (Basel). 2019;12(24):4052.
- Ensing GT, van Horn JR, van der Mei HC, Busscher HJ, Neut D. Copal bone cement is more effective in preventing biofilm formation than Palacos R-G. Clin Orthop Relat Res. 2008;466(6):1492-1498. https://doi.org/10.1007/s11999-008-0203-x
- Luo S, Jiang T, Long L, Yang Y, Yang X, Luo L, et al. A dual PMMA/calcium sulfate carrier of vancomycin is more effective than PMMA-vancomycin at inhibiting Staphylococcus aureus growth in vitro. FEBS Open Bio. 2020;10(4):552-560. https://doi.org/10.1002/2211-5463.12809
- Brooks JR, Dusane DH, Moore K, Gupta T, Delury C, Aiken SS, et al. Pseudomonas aeruginosa biofilm killing beyond the spacer by antibiotic-loaded calcium sulfate beads: an in vitro study. J Bone Jt Infect. 2021;6(5):119-129. https://doi.org/10.5194/jbji-6-119-2021
- Gonzalez-Martin M, Silva V, Poeta P, Corbera JA, Tejedor-Junco MT. Microbiological aspects of osteomyelitis in veterinary medicine: drawing parallels to the infection in human medicine. Vet Q. 2022;42(1):1-11. https://doi.org/10.1080/01652176.2021.2022244
- Diez-Pena E, Frutos G, Frutos P, Barrales-Rienda JM. Gentamicin sulphate release from a modified commercial acrylic surgical radiopaque bone cement. I. Influence of the gentamicin concentration on the release process mechanism. Chem Pharm Bull (Tokyo). 2002;50(9):1201-1208. https://doi.org/10.1248/cpb.50.1201
- Hsieh PH, Tai CL, Lee PC, Chang YH. Liquid gentamicin and vancomycin in bone cement: a potentially more cost-effective regimen. J Arthroplasty. 2009;24(1):125-130. https://doi.org/10.1016/j.arth.2008.01.131
- Oliver RA, Lovric V, Christou C, Aiken SS, Cooper JJ, Walsh WR. Application of calcium sulfate for dead space management in soft tissue: characterisation of a novel in vivo response. BioMed Res Int. 2018;2018:8065141.
- Ham K, Griffon D, Seddighi M, Johnson AL. Clinical application of tobramycin-impregnated calcium sulfate beads in six dogs (2002-2004). J Am Anim Hosp Assoc. 2008;44(6):320-326. https://doi.org/10.5326/0440320
- Uchino M, Sugo K, Naruse K, Uchida K, Hirakawa N, Toyama M, et al. Elution characteristics of vancomycin, gentamicin, and vancomycin/gentamicin combination from calcium phosphate cement. Adv Orthop Surg. 2015;2015:257925.
- McConoughey SJ, Howlin RP, Wiseman J, Stoodley P, Calhoun JH. Comparing PMMA and calcium sulfate as carriers for the local delivery of antibiotics to infected surgical sites. J Biomed Mater Res B Appl Biomater. 2015;103(4):870-877. https://doi.org/10.1002/jbm.b.33247
- Richelsoph KC, Webb ND, Haggard WO. Elution behavior of daptomycin-loaded calcium sulfate pellets: a preliminary study. Clin Orthop Relat Res. 2007;461(461):68-73. https://doi.org/10.1097/BLO.0b013e3181123889
- McPherson EJ, Dipane MV, Chowdhry M, Wassef AJ. Fabrication of antibiotic-loaded dissolvable calcium sulfate beads: an in vitro mixing lab utilizing various antibiotic mixing formulas. J Bone Jt Infect. 2021;6(9):405-412. https://doi.org/10.5194/jbji-6-405-2021
- Lewry AJ, Williamson J. The setting of gypsum plaster. J Mater Sci. 1994;29(21):5524-5528. https://doi.org/10.1007/BF00349943
- Armstrong DG, Stephan KT, Espensen EH, Lipsky BA, Boulton AJ. What is the shelf life of physician-mixed antibiotic-impregnated calcium sulfate pellets? J Foot Ankle Surg. 2003;42(5):302-304. https://doi.org/10.1016/S1067-2516(03)00307-7